Fundamentals Of Advanced Omics Technologies From Genes To Metabolites

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Publisher : Newnes
ISBN 13 : 0444626700
Total Pages : 488 pages
Book Rating : 4.07/5 ( download)

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Download or read book Fundamentals of Advanced Omics Technologies: From Genes to Metabolites written by and published by Newnes. This book was released on 2014-02-14 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA microarray analysis, next-generation sequencing technologies, genome-wide analysis of methylation and histone modifications, emerging nanotechniques in proteomics, imaging mass spectrometry in proteomics, recent quantitative proteomics approaches, and advances in high-resolution NMR-based metabolomics, as well as MS-based non-targeted metabolomics and metabolome analysis by CE-MS, global glycomics analyses, foodomics, and high resolution analytical tools for quantitative peptidomics. Key aspects related to chemometrics, bioinformatics, data treatment, data integration and systems biology, deep-sequencing data analysis, statistical approaches for the analysis of microarray data, the integration of transcriptome and metabolome data and computational approaches for visualization and integration of omics data are also covered. Covers the latest advances in instrumentation, experimental design, sample preparation, and data analysis Provides thorough explanations and descriptions of specific omics technologies Describes advanced tools and methodologies for data pretreatment, storage, curation and analysis, as well as data integration

Author :
Publisher : Elsevier
ISBN 13 : 0444626697
Total Pages : 497 pages
Book Rating : 4.91/5 ( download)

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Download or read book Applications of Advanced Omics Technologies: From Genes to Metabolites written by and published by Elsevier. This book was released on 2014-05-08 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains contributions concerning the application of the new instrumental and methodological developments in omics technologies, including those related to Genomics, Transcriptomics, Proteomics, Peptidomics and Metabolomics, Lipidomics and Foodomics. The16 chapters discuss in detail: innovative applications of functional gene microarrays for profiling microbial communities, microRNA profiling, novel genotyping applications using microarray technology in cancer research, next-generation sequencing applied to the study of human microbiome, emerging RNA-SEQ applications in food science, recent progress in plant proteomics, applications of gel-free proteomic approaches, the challenges and applications of proteomics tools for food authenticity, the role of salivary peptidomics in clinical applications, metabolomic approaches to the study of degenerative, cardiovascular and renal diseases, and neonatal medicine. Also covered are other omics applications such as profiling of genetically modified organisms, the fundamentals, applications and challenges of foodomics, and MS-based lipidomics. Moreover, this volume includes relevant and updated aspects on bioinformatics, data treatment, data integration and systems biology. This book complements the previous volume "Fundamentals of Advanced Omics Technologies: New Advances from Genes to Metabolites" that covered the fundamental aspects of these new omics technologies. Describes the latest applications of omics technologies Provides an excellent reference for applications of advanced omics techniques Includes advanced tools and methodologies for dealing with the data generated

Author :
Publisher : Elsevier
ISBN 13 : 9780444626516
Total Pages : 490 pages
Book Rating : 4.14/5 ( download)

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Download or read book Fundamentals of Advanced Omics Technologies: From Genes to Metabolites written by and published by Elsevier. This book was released on 2014-04-21 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA microarray analysis, next-generation sequencing technologies, genome-wide analysis of methylation and histone modifications, emerging nanotechniques in proteomics, imaging mass spectrometry in proteomics, recent quantitative proteomics approaches, and advances in high-resolution NMR-based metabolomics, as well as MS-based non-targeted metabolomics and metabolome analysis by CE-MS, global glycomics analyses, foodomics, and high resolution analytical tools for quantitative peptidomics. Key aspects related to chemometrics, bioinformatics, data treatment, data integration and systems biology, deep-sequencing data analysis, statistical approaches for the analysis of microarray data, the integration of transcriptome and metabolome data and computational approaches for visualization and integration of omics data are also covered. Covers the latest advances in instrumentation, experimental design, sample preparation, and data analysis Provides thorough explanations and descriptions of specific omics technologies Describes advanced tools and methodologies for data pretreatment, storage, curation and analysis, as well as data integration

Author : Wan Mohd Aizat
Publisher : Springer
ISBN 13 : 3319987585
Total Pages : 99 pages
Book Rating : 4.83/5 ( download)

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Download or read book Omics Applications for Systems Biology written by Wan Mohd Aizat and published by Springer. This book was released on 2018-10-31 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains omics at the most basic level, including how this new concept can be properly utilized in molecular and systems biology research. Most reviews and books on this topic have mainly focused on the technicalities and complexity of each omics’ platform, impeding readers to wholly understand its fundamentals and applications. This book tackles such gap and will be most beneficial to novice in this area, university students and even researchers. Basic workflow and practical guidance in each omics are also described, such that scientists can properly design their experimentation effectively. Furthermore, how each omics platform has been conducted in our institute (INBIOSIS) is also detailed, a comprehensive example on this topic to further enhance readers’ understanding. The contributors of each chapter have utilized the platforms in various manner within their own research and beyond. The contributors have also been interactively integrated and combined these different omics approaches in their research, being able to systematically write each chapter with the conscious knowledge of other inter-relating topics of omics. The potential readers and audience of this book can come from undergraduate and postgraduate students who wish to extend their comprehension in the topics of molecular biology and big data analysis using omics platforms. Furthermore, researchers and scientists whom may have expertise in basic molecular biology can extend their experimentation using the omics technologies and workflow outlined in this book, benefiting their research in the long run.

Author : Silvio Vaz Jr.
Publisher : Elsevier
ISBN 13 : 0323997368
Total Pages : 238 pages
Book Rating : 4.62/5 ( download)

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Download or read book Renewable Carbon written by Silvio Vaz Jr. and published by Elsevier. This book was released on 2022-07-01 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renewable Carbon: Science, Technology and Sustainability identifies production pathways and technologies for the production of chemicals and presents relevant information to bridge the gap between reaction engineering and process design. The book uses a multidisciplinary approach, focusing on important aspects of basic science, technological advantages (and hurdles), and key sustainability aspects. It incorporates organic, inorganic and biochemical synthesis and analyzes the myriad of technologies available, including nanotechnology, biotechnology and thermochemistry. Sections cover the synthesis of carbon derivatives through multiple pathways (Science), technologies available for its generation (Technology), and assess sustainability and new supply chains (Sustainability). This book will serve as a valuable reference for academics, research scientists and industry practitioners in green chemistry, chemical engineering, materials science and environmental engineering. Includes a review of sustainable feedstocks containing renewable carbon such as biomass, CO2 and recycling materials Provides a compendium of technologies to explore renewable carbon sources Compiles the most up-to-date information on renewable products and materials utilized in industry

Author : Veronica Ghini
Publisher : Springer Nature
ISBN 13 : 3031268598
Total Pages : 384 pages
Book Rating : 4.95/5 ( download)

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Download or read book Metabolomics and Its Impact on Health and Diseases written by Veronica Ghini and published by Springer Nature. This book was released on 2023-03-03 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.

Author : Ann M. Coulston
Publisher : Academic Press
ISBN 13 : 0128029471
Total Pages : 1075 pages
Book Rating : 4.73/5 ( download)

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Download or read book Nutrition in the Prevention and Treatment of Disease written by Ann M. Coulston and published by Academic Press. This book was released on 2017-04-28 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating disease and developing disease prevention strategies. Well-founded medical nutrition therapies can minimize disease development and related complications. Providing scientifically sound, creative, and effective nutrition interventions is both challenging and rewarding. Two new chapters on metabolomics and translational research, which have come to be used in nutrition research in recent years. The new areas of study are discussed with the perspective that the application of the scientific method is by definition an evolutionary process. A new chapter on Genetics and Diabetes which reviews the latest research on causal genetic variants and biological mechanisms responsible for the disease, and explores potential interactions with environmental factors such as diet and lifestyle. Includes all major "omics" – the exposome, metabolomics, genomics, and the gut microbiome. Expands the microbiota portions to reflect complexity of diet on gut microbial ecology, metabolism and health

Author : Shen Hu
Publisher : Springer Nature
ISBN 13 : 3030516520
Total Pages : 317 pages
Book Rating : 4.29/5 ( download)

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Download or read book Cancer Metabolomics written by Shen Hu and published by Springer Nature. This book was released on 2021-04-01 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling liquid chromatography - mass spectrometry, capillary ion chromatography - mass spectrometry, 2-D gas chromatography – mass spectrometry, capillary electrophoresis – mass spectrometry, nuclear magnetic resonance spectroscopy, shotgun lipidomics, tracer-based metabolomics, microbial metabolomics, mass spectrometry imaging for single cell metabolomics and functional metabolomics. In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translational applications of metabolomics in human cancers such as glioma, head and neck cancer, and gastric cancer. This new volume will be a unique reference source for cancer researchers and promote applications of metabolomics in understanding cancer metabolism.

Author : Noureddine Benkeblia
Publisher : CRC Press
ISBN 13 : 1439837074
Total Pages : 429 pages
Book Rating : 4.78/5 ( download)

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Download or read book OMICs Technologies written by Noureddine Benkeblia and published by CRC Press. This book was released on 2012-01-24 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the completion of the Human Genome Project, food and nutrition sciences have undergone a fundamental molecular transformation. New discoveries in molecular biology, analytical chemistry, and biochemistry have led to the development of new tools that are likely to revolutionize the study of food. OMICS Technologies: Tools for Food Science expl

Author : Peter Grunwald
Publisher : World Scientific Publishing Company
ISBN 13 : 1783269103
Total Pages : 1316 pages
Book Rating : 4.05/5 ( download)

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Download or read book Biocatalysis written by Peter Grunwald and published by World Scientific Publishing Company. This book was released on 2017-08-04 with total page 1316 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Completely Revised and Extended Edition with a significantly enhanced content, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway engineering, and de-novo computational design as actual research areas in biocatalysis. Information about different aspects of RNA technologies, and completely new Chapters on 'Fluorescent Proteins' and 'Biocatalysis and Nanotechnology' are also included.