Experimental Design For Laboratory Biologists

Author : Stanley E. Lazic
Publisher : Cambridge University Press
ISBN 13 : 1107074290
Total Pages : 429 pages
Book Rating : 4.93/5 ( download)

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Download or read book Experimental Design for Laboratory Biologists written by Stanley E. Lazic and published by Cambridge University Press. This book was released on 2016-12-08 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to designing lab-based biological experiments that have low bias, high precision and widely applicable results.

Author : David J. Glass
Publisher : CSHL Press
ISBN 13 : 0879697350
Total Pages : 211 pages
Book Rating : 4.58/5 ( download)

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Download or read book Experimental Design for Biologists written by David J. Glass and published by CSHL Press. This book was released on 2007 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Author : Gerald Peter Quinn
Publisher : Cambridge University Press
ISBN 13 : 9780521009768
Total Pages : 560 pages
Book Rating : 4.66/5 ( download)

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Download or read book Experimental Design and Data Analysis for Biologists written by Gerald Peter Quinn and published by Cambridge University Press. This book was released on 2002-03-21 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regression, analysis of variance, correlation, graphical.

Author : Robert E. Kohler
Publisher : University of Chicago Press
ISBN 13 : 0226450112
Total Pages : 341 pages
Book Rating : 4.17/5 ( download)

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Download or read book Landscapes and Labscapes written by Robert E. Kohler and published by University of Chicago Press. This book was released on 2010-11-15 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is it like to do field biology in a world that exalts experiments and laboratories? How have field biologists assimilated laboratory values and practices, and crafted an exact, quantitative science without losing their naturalist souls? In Landscapes and Labscapes, Robert E. Kohler explores the people, places, and practices of field biology in the United States from the 1890s to the 1950s. He takes readers into the fields and forests where field biologists learned to count and measure nature and to read the imperfect records of "nature's experiments." He shows how field researchers use nature's particularities to develop "practices of place" that achieve in nature what laboratory researchers can only do with simplified experiments. Using historical frontiers as models, Kohler shows how biologists created vigorous new border sciences of ecology and evolutionary biology.

Author : Martina Bremer
Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.49/5 ( download)

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Download or read book Statistics at the Bench written by Martina Bremer and published by . This book was released on 2010 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is a convenient bench companion for biologists, designed as a handy reference guide for elementary and intermediate statistical analyses. Statistical methods most frequently used in publications and reports, as well as guidelines for the interpretation of results, are explained using simple examples with complete instructions for Excel.

Author : Simon T. Bate
Publisher : Cambridge University Press
ISBN 13 : 1107030781
Total Pages : 327 pages
Book Rating : 4.87/5 ( download)

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Download or read book The Design and Statistical Analysis of Animal Experiments written by Simon T. Bate and published by Cambridge University Press. This book was released on 2014-03-13 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide scientists with a better understanding of statistics, improving their decision-making and reducing animal use.

Author : Martina Bremer
Publisher :
ISBN 13 : 9781621821120
Total Pages : 0 pages
Book Rating : 4.29/5 ( download)

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Download or read book Using R at the Bench written by Martina Bremer and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using R at the Bench: Step-by-Step Data Analytics for Biologists is a convenient bench-side handbook for biologists, designed as a handy reference guide for elementary and intermediate statistical analyses using the free/public software package known as "R." The expectations for biologists to have a more complete understanding of statistics are growing rapidly. New technologies and new areas of science, such as microarrays, next-generation sequencing, and proteomics, have dramatically increased the need for quantitative reasoning among biologists when designing experiments and interpreting results. Even the most routine informatics tools rely on statistical assumptions and methods that need to be appreciated if the scientific results are to be correct, understood, and exploited fully. Although the original Statistics at the Bench is still available for sale and has all examples in Excel, this new book uses the same text and examples in R. A new chapter introduces the basics of R: where to download, how to get started, and some basic commands and resources. There is also a new chapter that explains how to analyze next-generation sequencing data using R (specifically, RNA-Seq). R is powerful statistical software with many specialized packages for biological applications and Using R at the Bench: Step-by-Step Data Analytics for Biologists is an excellent resource for those biologists who want to learn R. This handbook for working scientists provides a simple refresher for those who have forgotten what they once knew and an overview for those wishing to use more quantitative reasoning in their research. Statistical methods, as well as guidelines for the interpretation of results, are explained using simple examples. Throughout the book, examples are accompanied by detailed R commands for easy reference.

Author : Natalie Kuldell PhD.
Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1491907533
Total Pages : 293 pages
Book Rating : 4.35/5 ( download)

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Download or read book BioBuilder written by Natalie Kuldell PhD. and published by "O'Reilly Media, Inc.". This book was released on 2015-06-22 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene

Author : Steve McKillup
Publisher : Cambridge University Press
ISBN 13 : 1139502948
Total Pages : 430 pages
Book Rating : 4.48/5 ( download)

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Download or read book Statistics Explained written by Steve McKillup and published by Cambridge University Press. This book was released on 2011-11-03 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of statistics and experimental design is essential for life science studies, but many students lack a mathematical background and some even dread taking an introductory statistics course. Using a refreshingly clear and encouraging reader-friendly approach, this book helps students understand how to choose, carry out, interpret and report the results of complex statistical analyses, critically evaluate the design of experiments and proceed to more advanced material. Taking a straightforward conceptual approach, it is specifically designed to foster understanding, demystify difficult concepts and encourage the unsure. Even complex topics are explained clearly, using a pictorial approach with a minimum of formulae and terminology. Examples of tests included throughout are kept simple by using small data sets. In addition, end-of-chapter exercises, new to this edition, allow self-testing. Handy diagnostic tables help students choose the right test for their work and remain a useful refresher tool for postgraduates.

Author : Theodore Garland
Publisher : Univ of California Press
ISBN 13 : 052094447X
Total Pages : 750 pages
Book Rating : 4.73/5 ( download)

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Download or read book Experimental Evolution written by Theodore Garland and published by Univ of California Press. This book was released on 2009-12-03 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental approaches to evolution provide indisputable evidence of evolution by directly observing the process at work. Experimental evolution deliberately duplicates evolutionary processes—forcing life histories to evolve, producing adaptations to stressful environmental conditions, and generating lineage splitting to create incipient species. This unique volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field’s full range of research—from selection in the laboratory to the manipulation of populations in the wild. It provides work on such key biological problems as the evolution of Darwinian fitness, sexual reproduction, life history, athletic performance, and learning.