Experimental And Surgical Technique In The Rat

Author : H. B. Waynforth
Publisher :
ISBN 13 : 9780127388502
Total Pages : 269 pages
Book Rating : 4.08/5 ( download)

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Download or read book Experimental and Surgical Technique in the Rat written by H. B. Waynforth and published by . This book was released on 1980-01-01 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures. One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training. This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features * All surgical techniques have been revised and updated * A new section on anesthesia and post-operative care has been included * Presents new techniques, particularly cannulation

Author : H. Bryan Waynforth
Publisher :
ISBN 13 : 9780127388519
Total Pages : 382 pages
Book Rating : 4.16/5 ( download)

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Download or read book Experimental and Surgical Technique in the Rat written by H. Bryan Waynforth and published by . This book was released on 1992 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures. One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training. This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features * All surgical techniques have been revised and updated * A new section on anesthesia and post-operative care has been included * Presents new techniques, particularly cannulation

Author : Alfredo Rigalli
Publisher : CRC Press
ISBN 13 : 1420093274
Total Pages : 232 pages
Book Rating : 4.78/5 ( download)

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Download or read book Experimental Surgical Models in the Laboratory Rat written by Alfredo Rigalli and published by CRC Press. This book was released on 2016-04-19 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: An All-Inclusive Guide to Surgical Techniques on RatsThe design of an adequate surgical model, like the choice of the animal model itself, is extremely important for obtaining reliable valuable data. Experimental Surgical Models in the Laboratory Rat summarizes a series of techniques that were applied in the Bone Biology Laboratories, School of Med

Author : Flecknell
Publisher : Academic Press
ISBN 13 : 9780128127889
Total Pages : pages
Book Rating : 4.80/5 ( download)

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Download or read book Experimental and Surgical Techniques in the Rat and Mouse written by Flecknell and published by Academic Press. This book was released on 2018-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Peter Girman
Publisher : Springer
ISBN 13 : 3319145592
Total Pages : 252 pages
Book Rating : 4.94/5 ( download)

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Download or read book Rat Experimental Transplantation Surgery written by Peter Girman and published by Springer. This book was released on 2015-11-16 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into ‘General’ and ‘Specific’ sections. The ‘General’ section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant’s used in rat models, a description of basic surgical techniques and blood sampling. The ‘Specific’ section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe ‘tips and tricks’ including practical advice and recommendations.

Author : Miroslaw Janowski
Publisher : Humana
ISBN 13 : 9781493937288
Total Pages : 0 pages
Book Rating : 4.86/5 ( download)

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Download or read book Experimental Neurosurgery in Animal Models written by Miroslaw Janowski and published by Humana. This book was released on 2016-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.

Author : Sherif Amr
Publisher : BoD – Books on Demand
ISBN 13 : 1789230128
Total Pages : 190 pages
Book Rating : 4.23/5 ( download)

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Download or read book Issues in Flap Surgery written by Sherif Amr and published by BoD – Books on Demand. This book was released on 2018-04-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of flap surgery parallels the increasing complexity of soft-tissue defects needing reconstruction. Random and pedicled flaps as well as free muscle and fasciocutaneous flaps have helped to reconstruct single soft-tissue defects. The multiplicity of defects needing reconstruction and donor-site morbidity in addition to tailored reconstruction have called for a revision of flap concepts in favor of perforator flaps. Unfortunately, we are faced with increasingly complex reconstructive issues. New reconstructive techniques, such as the Ilizarov method, have made orthopedic reconstruction after high energy and complex trauma possible. Revision surgeries after tumor resection and plastic surgery have brought about soft-tissue defects associated with extensive fibrosis and necrosis. As a result, previously nonsalvageable limbs have been salvaged. The reconstructive surgeons are faced with the following situations: multiple soft-tissue defects, extensive fibrosis, possibility of major vessel loss, and possibility of damage of several perforators.

Author : Peter Girman
Publisher :
ISBN 13 : 9783319145600
Total Pages : pages
Book Rating : 4.06/5 ( download)

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Download or read book Rat Experimental Transplantation Surgery written by Peter Girman and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into 'General' and 'Specific' sections. The 'General' section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant's used in rat models, a description of basic surgical techniques and blood sampling. The 'Specific' section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe 'tips and tricks' including practical advice and recommendations.

Author : Patrick Sharp
Publisher : CRC Press
ISBN 13 : 1439829861
Total Pages : 403 pages
Book Rating : 4.68/5 ( download)

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Download or read book The Laboratory Rat, Second Edition written by Patrick Sharp and published by CRC Press. This book was released on 2012-12-11 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.57/5 ( download)

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Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.