Erythrocytes Of The Rhesus And Cynomolgus Monkeys

Author : Chester A. Glomski
Publisher : CRC Press
ISBN 13 : 1498733603
Total Pages : 254 pages
Book Rating : 4.01/5 ( download)

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Download or read book Erythrocytes of the Rhesus and Cynomolgus Monkeys written by Chester A. Glomski and published by CRC Press. This book was released on 2015-12-23 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Erythrocytes of the Rhesus and Cynomolgus Monkeys addresses the morphologic, quantitative, and generative aspects of the erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus monkey Macaca fascicularis (long-tailed macaque, crab-eating monkey). These two species are the most commonly selected nonhuman primates for basic science and clinical medical investigations. The hemopoietic cells of man and the rhesus monkey display an intimate homogeneity. Their functional activities are close and at times identical. The cynomolgus monkey was enlisted in biomedical studies at a time when rhesus monkeys were not available in sufficient quantities. It has gained increased use in the Far East and in the Western world. It is, for example, employed in the current development of a vaccine against the deadly Ebola virus. The authors of the book discuss the erythropoietic profiles of normal and abnormal macaques of both sexes and of all age groups as investigated with contemporary electronic methodologies. They cover the role of stress as it is perceived by the monkey and how it impacts erythrocellular values, and how to train the monkey to be a cooperative, unperturbed subject for hematologic study. Additional topics include the role of medication in deriving normal physiologic erythrocellular data, the development of the precursors of the erythrocyte (normoblasts), the morphologic analysis of the megaloblastic series of abnormal erythroid cells, the analysis of erythropoiesis in bone marrow, the relationship of the simian immunodeficiency virus and erythropoiesis, erythrocyte life span, and parasitic invasion of the red cell.

Author : Gerard Meurant
Publisher : Elsevier
ISBN 13 : 9780080546322
Total Pages : 432 pages
Book Rating : 4.23/5 ( download)

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Download or read book A Dictionary of Virology written by Gerard Meurant and published by Elsevier. This book was released on 2001-08-22 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of A Dictionary of Virology offers an authoritative, concise, and up-to-date list of all viruses affecting vertebrate species, from humans to fish. It has been completely revised since the 1997 edition to include 25% more entries, including many completely new viruses. The entries have been restructured so that all viruses are listed and classified in accordance with the standards set by the 7th Report of the ICTV. The extensive cross-referencing and illustrative tables further enhance the utility of this reference.

Author : Joy A. Cavagnaro
Publisher : CRC Press
ISBN 13 : 1000471853
Total Pages : 952 pages
Book Rating : 4.54/5 ( download)

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Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 770 pages
Book Rating : 4.01/5 ( download)

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Download or read book Journal written by National Cancer Institute (U.S.) and published by . This book was released on 1960 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.67/5 ( download)

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Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1962 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : George Robert Coatney
Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.58/5 ( download)

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Download or read book The Primate Malarias written by George Robert Coatney and published by . This book was released on 1971 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : 750 pages
Book Rating : 4.51/5 ( download)

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Download or read book The American Journal of Tropical Medicine and Hygiene written by and published by . This book was released on 1980 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.43/5 ( download)

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Download or read book Literature Search written by National Library of Medicine (U.S.) and published by . This book was released on 1987 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Larry J. Anderson
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805563531
Total Pages : 163 pages
Book Rating : 4.36/5 ( download)

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Download or read book Human Parvovirus B19 written by Larry J. Anderson and published by Karger Medical and Scientific Publishers. This book was released on 1996-12-31 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with comprehensive and detailed reviews of subjects important to understanding parvovirus B19, including the structure and biochemistry of the virus, the clinical and epidemiological features of infection, the diagnosis of infection, the pathophysiology of disease, the host's immune response, and the treatment and prevention of disease. Its expert contributions make this publication an essential and timely resource for clinicians, epidemiologists and public health policymakers in their endeavor to optimize treatment and prevention. It will also be appreciated by laboratory researchers interested in the physical and biological properties of the virus and the pathogenesis of B19 disease.

Author : Alys Bradley
Publisher : Academic Press
ISBN 13 : 012813089X
Total Pages : 628 pages
Book Rating : 4.96/5 ( download)

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Download or read book Spontaneous Pathology of the Laboratory Non-human Primate written by Alys Bradley and published by Academic Press. This book was released on 2023-06-20 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. Contains color illustrations that depict the most common lesions to augment descriptions Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP) Provides pathologists with common terms that are compliant with the FDA’s Standard for Exchange of Nonclinical Data (SEND) guidelines