Dynamin Superfamily Gtpases

Author : Rajesh Ramachandran
Publisher : Humana
ISBN 13 : 9781071606780
Total Pages : 221 pages
Book Rating : 4.86/5 ( download)

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Download or read book Dynamin Superfamily GTPases written by Rajesh Ramachandran and published by Humana. This book was released on 2021-06-26 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides methods and protocols on dynamin superfamily GTPases. Chapters are divided into three parts; detailing expression, purification, initial biochemical steps, undescribed analytical techniques, and biophysical and cellular characterization of DSPs in membrane remodeling, fission and fusion. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Dynamin Superfamily GTPases: Methods and Protocols to ensure successful results in the further study of this vital field.

Author : Rajesh Ramachandran
Publisher : Humana
ISBN 13 : 9781071606759
Total Pages : 0 pages
Book Rating : 4.51/5 ( download)

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Download or read book Dynamin Superfamily GTPases written by Rajesh Ramachandran and published by Humana. This book was released on 2020-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides methods and protocols on dynamin superfamily GTPases. Chapters are divided into three parts; detailing expression, purification, initial biochemical steps, undescribed analytical techniques, and biophysical and cellular characterization of DSPs in membrane remodeling, fission and fusion. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Dynamin Superfamily GTPases: Methods and Protocols to ensure successful results in the further study of this vital field.

Author : Joan Marsh
Publisher : John Wiley & Sons
ISBN 13 : 0470514469
Total Pages : 304 pages
Book Rating : 4.67/5 ( download)

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Download or read book The GTPase Superfamily written by Joan Marsh and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a multidisciplinary approach, it features contributions and discussions of the latest research from leading scientists working on all aspects of GTPase activity. Covers all known members of the important superfamily of enzymes--the GTPases. Considers numerous key cellular functions and how they are regulated by GTPases. Also describes various regulatory proteins that modulate GTPase activity.

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642783457
Total Pages : 638 pages
Book Rating : 4.56/5 ( download)

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Download or read book GTPases in Biology II written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: The GTPase switch appears to be almost as old as life itself, and nature has adapted it to a variety of purposes. This two-volume work surveys the major classes of GTPases, including their role in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer. 80 chapters contain much previously unpublished data and, at the rate the extended family of GTPases is growing, it is unlikely that it will again sit for a group portrait such as this. Thus, this could well become the standard reference work.

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642782671
Total Pages : 708 pages
Book Rating : 4.71/5 ( download)

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Download or read book GTPases in Biology I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The GTPase switch appears to be almost as old as life itself, and nature has adapted it to a variety of purposes. This two-volume work surveys the major classes of GTPases, including their role in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer. 80 chapters contain much previously unpublished data and, at the rate the extended family of GTPases is growing, it is unlikely that it will again sit for a group portrait such as this. Thus, this could well become the standard reference work.

Author : Ed Manser
Publisher : Springer Science & Business Media
ISBN 13 : 1592592813
Total Pages : 259 pages
Book Rating : 4.14/5 ( download)

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Download or read book GTPase Protocols written by Ed Manser and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last 10 years researchers have firmly established key roles for R- related GTPases in almost every aspect of cell biology. In the 1980s the pro- oncogene Ras itself was the focus of interest, though in the 1990s this shifted to the increasing variety of Ras-related proteins. In this new decade much yet needs to be done to establish the role for all the small GTPases now uncovered by the human genome project. In particular, these GTPases need to be und- stood in the appropriate biochemical and cellular contexts. In the process of trying to uncover the role of these versatile proteins, a variety of novel te- niques and methodologies has been developed. These now enable investi- tors to move easily within a diversity of fields ranging from structural studies to real-time in vivo analysis of a GTPase. In recognition of the need for access to key background methodologies, GTPase Protocols: The Ras Superfamily is devoted to techniques that are pr- ently widely used and that will continue to be the standard for researchers worldwide. Each chapter is aimed at supplying detailed methodologies to allow reproduction in any laboratory, while also providing the general pr- ciples on which the methods are based. Some of the techniques grouped in the first section apply broadly to small GTPases, whereas others in Part II are more applicable within each GTPase subfamily.

Author : Alfred Wittinghofer
Publisher : Springer
ISBN 13 : 3709118069
Total Pages : 447 pages
Book Rating : 4.61/5 ( download)

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Download or read book Ras Superfamily Small G Proteins: Biology and Mechanisms 1 written by Alfred Wittinghofer and published by Springer. This book was released on 2014-09-22 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.

Author : Juan Carlos Lacal
Publisher : CRC Press
ISBN 13 : 9780849352140
Total Pages : 554 pages
Book Rating : 4.42/5 ( download)

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Download or read book The ras Superfamily of GTPases written by Juan Carlos Lacal and published by CRC Press. This book was released on 1993-06-11 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ras Superfamily of GTPases presents the most comprehensive compilation of information available regarding aspects of the putative function of small ras-related GTPases. The book's chapters were written by the world's most prominent scientists in this field and cover such topics as the structure and properties of ras proteins, ras function, the ras superfamily in general, and the functional regulation of ras and ras-related GTPases. The book will benefit cell biologists, oncologists, neurobiologists, molecular biologists, and others interested in the topic.

Author : Juan Carlos Lacal
Publisher : CRC Press
ISBN 13 : 1351356852
Total Pages : 548 pages
Book Rating : 4.55/5 ( download)

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Download or read book The ras Superfamily of GTPases (1993) written by Juan Carlos Lacal and published by CRC Press. This book was released on 2017-11-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ras Superfamily of GTPases presents the most comprehensive compilation of information available regarding aspects of the putative function of small ras-related GTPases. The book's chapters were written by the world's most prominent scientists in this field and cover such topics as the structure and properties of ras proteins, ras function, the ras superfamily in general, and the functional regulation of ras and ras-related GTPases. The book will benefit cell biologists, oncologists, neurobiologists, molecular biologists, and others interested in the topic.

Author : William Edward Balch
Publisher : Academic Press
ISBN 13 : 9780121828127
Total Pages : 780 pages
Book Rating : 4.23/5 ( download)

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Download or read book Regulators and Effectors of Small GTPases written by William Edward Balch and published by Academic Press. This book was released on 2006 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, the study of Ras Family GTPases has witnessed a plethora of new directions and trends. With regards to the founding member of the Ras superfamily, the study of Ras in oncogenesis has seen the development and application of more advanced model cell culture and animal systems. The discovery of mutationally activated B-Raf in human cancers has injected renewed interest in this classical effector pathway of Ras. *Includes a database for Ras family proteins and their effectors and regulators *Complimentary to volume 406 coverage of the Rho family *Over 150 international contributors