Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations Hplc And Hptlc Techniques

Author : Satish Y. Gabhe
Publisher : diplom.de
ISBN 13 : 3954898071
Total Pages : 108 pages
Book Rating : 4.77/5 ( download)

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Download or read book Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations: HPLC And HPTLC Techniques written by Satish Y. Gabhe and published by diplom.de. This book was released on 2015-08-01 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details: 1. Development and validation of a HPTLC-densitometric method for concurrent estimation of metformin hydrochloride, pioglitazone hydrochloride and gliclazide in combined dosage form. 2. Development and validation of a HPTLC method for simultaneous estimation of moxifloxacin hydrochloride and dexamethasone sodium phosphate in combined pharmaceutical dosage form. 3. Development and validation of a RP-HPLC method for simultaneous estimation of ciprofloxacin hydrochloride and dexamethasone in combined dosage form, which is a better alternative to existing ones. The developed analytical methods are simple, selective, accurate, robust, and precise with shorter analysis time for the analysis of drug/s in combined pharmaceutical dosage forms. All the developed HPTLC and HPLC methods have been validated as per ICH Q2 (R1) guideline. Developed analytical methods could boost analytical researchers to work more efficiently in the field of analytical method development and validation of Pharmaceutical dosage forms.

Author : Satish Gabhe
Publisher : GRIN Verlag
ISBN 13 : 3656633231
Total Pages : 109 pages
Book Rating : 4.35/5 ( download)

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Download or read book Simultaneous Estimation of Some Drugs in Bulk and in their Formulation by Chromatographic Methods. written by Satish Gabhe and published by GRIN Verlag. This book was released on 2014-04-09 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, Pharmacy, , course: MASTER OF PHARMACY (Quality Assurance Techniques), language: English, abstract: A number of new drug entities, modifications of existing ones, and multi-component formulations are entering the market, every year. Development of simple analytical methods for analysis of various drugs in multi - component formulations is a tricky task for an analytical researcher. As analytical techniques are used throughout drug development, manufacturing, release of drug products, the reliability of their results is essential. Chromatographic methods are most useful and powerful techniques for qualitative and quantitative determination of drug/s. Therefore, appropriate validation to demonstrate the performance and suitability of the analytical method is much more than a formal requirement. Hence, there is need to develop and validate correct analytical method for these medicine/s. This book details, - Development and validation of HPTLC - densitometric method for concurrent estimation of metformin hydrochloride, pioglitazone hydrochloride and gliclazide in combined dosage form. - Development and validation of HPTLC method for simultaneous estimation of moxifloxacin hydrochloride and dexamethasone sodium phosphate in combined pharmaceutical dosage form. - Development and validation of RP - HPLC method for simultaneous estimation of ciprofloxacin hydrochloride and dexamethasone in combined dosage form, which is better alternative to existing one. The developed analytical methods are simple, selective, accurate, robust, and precise with shorter analysis time for the analysis of drug/s in combined pharmaceutical dosage forms. All the developed HPTLC and HPLC methods have been validated as per ICH Q2 (R1) guidelines. Developed analytical methods could boost analytical researcher to work more efficiently in the field of analytical method development and validation of Pharmaceutical dosage forms.

Author : Michael E. Swartz
Publisher : CRC Press
ISBN 13 : 1482229773
Total Pages : 95 pages
Book Rating : 4.76/5 ( download)

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Download or read book Analytical Method Development and Validation written by Michael E. Swartz and published by CRC Press. This book was released on 2018-10-03 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes analytical methods development, optimization and validation, and provides examples of successful methods development and validation in high-performance liquid chromatography (HPLC) areas. The text presents an overview of Food and Drug Administration (FDA)/International Conference on Harmonization (ICH) regulatory guidelines, compliance with validation requirements for regulatory agencies, and methods validation criteria stipulated by the US Pharmacopia, FDA and ICH.

Author : John A. Adamovics
Publisher : Routledge
ISBN 13 : 1351460854
Total Pages : 542 pages
Book Rating : 4.59/5 ( download)

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Download or read book Chromatographic Analysis of Pharmaceuticals written by John A. Adamovics and published by Routledge. This book was released on 2017-09-29 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and revised throughout. Second Edition explores the chromatographic methods used for the measurement of drugs, impurities, and excipients in pharmaceutical preparations--such as tablets, ointments, and injectables. Contains a 148-page table listing the chromatographic data of over 1300 drugs and related substances--including sample matrix analyzed, sample handling procedures, column packings, mobile phase, mode of detection, and more.

Author : Mantu K. Ghosh
Publisher : Springer Science & Business Media
ISBN 13 : 3642765068
Total Pages : 599 pages
Book Rating : 4.63/5 ( download)

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Download or read book HPLC Methods on Drug Analysis written by Mantu K. Ghosh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dramatic development of chromatographic techniques, specially high per formance or high pressure liquid chromatography (HPLC) has made possible the easy analysis of organic compounds, including drugs and drug components, for last two decades. This rapid increase and improvement of analytical methodology with HPLC has enabled researchers and scientists to cope with other scientific and instru mental developments in their fields of work. Thousands of impressive and original scientific publications, text books and monographs describe the techniques for drug analysis with high performance liquid chromatography. However, no concise presentation of the general proper ties of the drugs and their HPLC methodology exists together in the market. This work contains the general properties necessary for the analysis of 232 drugs as well as the HPLC methods for many other drugs and drug components. It is hoped that it will fill a gap and provide a precise survey of the HPLC methods for drug analysis. It is intended as an immediate guide in the laboratory and will be of help to the scientists, researchers and technicians in the field of analysis.

Author : Digbijay Kumar
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783659438691
Total Pages : 108 pages
Book Rating : 4.93/5 ( download)

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Download or read book Development and Validation of HPLC Method for Combined Dosage Form written by Digbijay Kumar and published by LAP Lambert Academic Publishing. This book was released on 2013 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical products formulated with more than one drug, typically referred to as combination products, are intended to meet previously unmet patients need by combining the therapeutic effects of two or more drugs in one product. These combination products can present daunting challenges to the analytical chemist responsible for the development and validation of analytical methods. This presentation will discuss the development and validation of analytical method Spectrophotometric and High performance liquid chromatography (HPLC), for drug products containing more than one active ingredient. This book deals with various approaches applied for the development and validation of analytical method for paracetamol and pamabrom.

Author : Lukasz Komsta
Publisher : CRC Press
ISBN 13 : 1466507160
Total Pages : 1067 pages
Book Rating : 4.66/5 ( download)

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Download or read book Thin Layer Chromatography in Drug Analysis written by Lukasz Komsta and published by CRC Press. This book was released on 2013-12-20 with total page 1067 pages. Available in PDF, EPUB and Kindle. Book excerpt: Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date

Author : Gregory K. Webster
Publisher : CRC Press
ISBN 13 : 042951039X
Total Pages : 567 pages
Book Rating : 4.97/5 ( download)

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Download or read book Chromatographic Methods Development written by Gregory K. Webster and published by CRC Press. This book was released on 2019-10-28 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics, and vendors in the field. This book is an inclusive guide to developing all chromatographic methods (such as liquid chromatography and gas chromatography). It covers modern techniques for developing methods using chromatographic development software, requirements for validations, discussion on orthogonality, and how to transfer methods from HPLC to UHPLC. The text introduces some newer techniques that are heavily employed by chemists analyzing proteins and RNAi, as well as novel techniques such as counter current chromatography. This book is valuable for both the novice starting out in undergraduate labs and those who are new to the pharmaceutical industry and is a useful reference for seasoned analysts.

Author : George Lunn
Publisher : John Wiley & Sons
ISBN 13 : 0471711675
Total Pages : 743 pages
Book Rating : 4.74/5 ( download)

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Download or read book HPLC Methods for Recently Approved Pharmaceuticals written by George Lunn and published by John Wiley & Sons. This book was released on 2005-05-06 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable resource for busy researchers Your time is valuable-too valuable to spend hunting through the technical literature in search of the right HPLC assay techniques for your projects. With HPLC Methods for Recently Approved Pharmaceuticals, you'll quickly identify and replicate the ideal procedures for your project needs, without having to refer to original source publications. More of your time can then be spent in the lab, not the library. Covering the relevant world literature through 2003, this book picks up where Dr. Lunn's acclaimed HPLC Methods for Pharmaceutical Analysis left off. It arms you with established HPLC assay techniques for hundreds of newly approved drugs, as well as drugs for which assay methods were only recently developed. Combining detailed descriptions of procedures with specially annotated references, this practical handbook gives you: * HPLC methods for 390 commonly prescribed pharmaceutical compounds * Various procedures for each drug listed together-making it easy to mix and match for customized approaches * Methods for drugs in biological fluids and for bulk and formulated drugs * Chemical structures, molecular weights and formulas, and CAS Registry Numbers * Cross-references to The Merck Index * Retention times of other drugs that can be assayed using the same methods

Author : Simon Fong
Publisher : Springer Nature
ISBN 13 : 9811952248
Total Pages : 763 pages
Book Rating : 4.41/5 ( download)

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Download or read book ICT Analysis and Applications written by Simon Fong and published by Springer Nature. This book was released on 2022-11-05 with total page 763 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes new technologies and discusses future solutions for ICT design infrastructures, as reflected in high-quality papers presented at the 7th International Conference on ICT for Sustainable Development (ICT4SD 2022), held in Goa, India, on July 29–30, 2022. The book covers the topics such as big data and data mining, data fusion, IoT programming toolkits and frameworks, green communication systems and network, use of ICT in smart cities, sensor networks and embedded system, network and information security, wireless and optical networks, security, trust, and privacy, routing and control protocols, cognitive radio and networks, and natural language processing. Bringing together experts from different countries, the book explores a range of central issues from an international perspective.