Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 288974101X
Total Pages : 1671 pages
Book Rating : 4.14/5 ( download)

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Book Synopsis Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response by :

Download or read book Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response written by and published by Frontiers Media SA. This book was released on 2023-01-25 with total page 1671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I.A An outbreak of a respiratory disease first reported in Wuhan, China in December 2019 and the causative agent was discovered in January 2020 to be a novel betacoronovirus of the same subgenus as SARS-CoV and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) has rapidly disseminated worldwide, with clinical manifestations ranging from mild respiratory symptoms to severe pneumonia and a fatality rate estimated around 2%. Person to person transmission is occurring both in the community and healthcare settings. The World Health Organization (WHO) has recently declared the COVID-19 epidemic a public health emergency of international concern. The ongoing outbreak presents many clinical and public health management challenges due to limited understanding of viral pathogenesis, risk factors for infection, natural history of disease including clinical presentation and outcomes, prognostic factors for severe illness, period of infectivity, modes and extent of virus inter-human transmission, as well as effective preventive measures and public health response and containment interventions. There are no antiviral treatment nor vaccine available but fast track research and development efforts including clinical therapeutic trials are ongoing across the world. Managing this serious epidemic requires the appropriate deployment of limited human resources across all cadres of health care and public health staff, including clinical, laboratory, managerial and epidemiological data analysis and risk assessment experts. It presents challenges around public communication and messaging around risk, with the potential for misinformation and disinformation. Therefore, integrated operational research and intervention, learning from experiences across different fields and settings should contribute towards better understanding and managing COVID-19. This Research Topic aims to highlight interdisciplinary research approaches deployed during the COVID-19 epidemic, addressing knowledge gaps and generating evidence for its improved management and control. It will incorporate critical, theoretically informed and empirically grounded original research contributions using diverse approaches, experimental, observational and intervention studies, conceptual framing, expert opinions and reviews from across the world. The Research Topic proposes a multi-dimensional approach to improving the management of COVID-19 with scientific contributions from all areas of virology, immunology, clinical microbiology, epidemiology, therapeutics, communications as well as infection prevention and public health risk assessment and management studies.

Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response (volume I.B)

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832522300
Total Pages : 1127 pages
Book Rating : 4.01/5 ( download)

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Book Synopsis Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response (volume I.B) by : Zisis Kozlakidis

Download or read book Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response (volume I.B) written by Zisis Kozlakidis and published by Frontiers Media SA. This book was released on 2023-04-25 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I.B An outbreak of a respiratory disease first reported in Wuhan, China in December 2019 and the causative agent was discovered in January 2020 to be a novel betacoronovirus of the same subgenus as SARS-CoV and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) has rapidly disseminated worldwide, with clinical manifestations ranging from mild respiratory symptoms to severe pneumonia and a fatality rate estimated around 2%. Person to person transmission is occurring both in the community and healthcare settings. The World Health Organization (WHO) has recently declared the COVID-19 epidemic a public health emergency of international concern. The ongoing outbreak presents many clinical and public health management challenges due to limited understanding of viral pathogenesis, risk factors for infection, natural history of disease including clinical presentation and outcomes, prognostic factors for severe illness, period of infectivity, modes and extent of virus inter-human transmission, as well as effective preventive measures and public health response and containment interventions. There are no antiviral treatment nor vaccine available but fast track research and development efforts including clinical therapeutic trials are ongoing across the world. Managing this serious epidemic requires the appropriate deployment of limited human resources across all cadres of health care and public health staff, including clinical, laboratory, managerial and epidemiological data analysis and risk assessment experts. It presents challenges around public communication and messaging around risk, with the potential for misinformation and disinformation. Therefore, integrated operational research and intervention, learning from experiences across different fields and settings should contribute towards better understanding and managing COVID-19. This Research Topic aims to highlight interdisciplinary research approaches deployed during the COVID-19 epidemic, addressing knowledge gaps and generating evidence for its improved management and control. It will incorporate critical, theoretically informed and empirically grounded original research contributions using diverse approaches, experimental, observational and intervention studies, conceptual framing, expert opinions and reviews from across the world. The Research Topic proposes a multi-dimensional approach to improving the management of COVID-19 with scientific contributions from all areas of virology, immunology, clinical microbiology, epidemiology, therapeutics, communications as well as infection prevention and public health risk assessment and management studies.

Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.B)

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Publisher : Frontiers Media SA
ISBN 13 : 2832524990
Total Pages : 815 pages
Book Rating : 4.92/5 ( download)

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Book Synopsis Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.B) by : Thomas Rawson

Download or read book Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.B) written by Thomas Rawson and published by Frontiers Media SA. This book was released on 2023-05-31 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.

Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.A)

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889764656
Total Pages : 771 pages
Book Rating : 4.55/5 ( download)

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Book Synopsis Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.A) by : Thomas Rawson

Download or read book Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.A) written by Thomas Rawson and published by Frontiers Media SA. This book was released on 2023-05-31 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.

Prevention And Control Of Covid-19

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Author :
Publisher : World Scientific
ISBN 13 : 9811220514
Total Pages : 72 pages
Book Rating : 4.17/5 ( download)

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Book Synopsis Prevention And Control Of Covid-19 by :

Download or read book Prevention And Control Of Covid-19 written by and published by World Scientific. This book was released on 2020-04-15 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shanghai COVID-19 Medical Treatment Expert Team edits this timely guide for effective prevention and control of COVID-19. Readers will obtain useful guidance on prevention and control of COVID-19 in different places ranging from homes, outdoors, workplaces, etc. You will know 'What is the purpose and significance of home quarantine?', ' When do you need to wear a mask?', 'How should you wash your hands?', 'Do you need to wear a mask in an elevator?', 'What foods are safe to eat and what are not?', 'How to deal with express parcels from major epidemic areas or other areas?' and many other useful tips.Related Link(s)

Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19

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Author :
Publisher : IGI Global
ISBN 13 : 1799882268
Total Pages : 352 pages
Book Rating : 4.68/5 ( download)

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Book Synopsis Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 by : El Hiba, Omar

Download or read book Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 written by El Hiba, Omar and published by IGI Global. This book was released on 2021-08-13 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization (WHO), coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus (SARS-Cov2), which may cause mild to moderate respiratory complications in most infected people. Older people and those with chronic and/or acute illnesses may present serious complications. Underlying mechanisms of the cellular responses to the virus are not fully revealed; therefore, understanding the pathophysiology of COVID-19 is crucial to provide efficient data to define the appropriate and effective therapeutic strategies to cure and prevent COVID-19-associated complications. The Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 summarizes and assembles the published data on COVID-19 and provides an answer to the reader for the mystery of SARS-Cov2’s impact on human health through a deep analysis of the current data available in the literature. This book addresses the epidemiology and infectious patterns of the disease and the recent pathophysiological mechanisms of the disease and relationships to the medical history of the patient. Covering topics from the tie between COVID-19 and respiratory disease to vaccination information, this comprehensive reference source is ideal for clinicians, health professionals, pathologists, virologists, researchers, academicians, and medical and PhD students.

COVID-19: Diagnosis and Management-Part I

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Publisher : Bentham Science Publishers
ISBN 13 : 1681088096
Total Pages : 223 pages
Book Rating : 4.99/5 ( download)

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Book Synopsis COVID-19: Diagnosis and Management-Part I by : Neeraj Mittal

Download or read book COVID-19: Diagnosis and Management-Part I written by Neeraj Mittal and published by Bentham Science Publishers. This book was released on 2021-06-04 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings. This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives. Key Features: Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students. Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19. Six chapters in the first part which focus on clinical basics of COVID-19. Six chapters in the first part which cover broader topics for practical infection control. Multiple tables and figures which summarize and highlight important points. Presents a summary of the current standards for the evaluation and diagnosis of COVID-19. Features a detailed list of references, abbreviations, and symbols. This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

COVID-19: Diagnosis and Management-Part II

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 168108807X
Total Pages : 225 pages
Book Rating : 4.75/5 ( download)

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Book Synopsis COVID-19: Diagnosis and Management-Part II by : Neeraj Mittal

Download or read book COVID-19: Diagnosis and Management-Part II written by Neeraj Mittal and published by Bentham Science Publishers. This book was released on 2021-06-28 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings. This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives. Key Features: Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students. Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19. Six chapters in the first part which focus on clinical basics of COVID-19. Six chapters in the second part which cover broader topics for practical infection control. Multiple tables and figures which summarize and highlight important points. Presents a summary of the current standards for the evaluation and diagnosis of COVID-19. Features a detailed list of references, abbreviations, and symbols. This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

SARS-CoV2 (COVID-19) Pandemic Control and Prevention

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Author :
Publisher : Taylor & Francis
ISBN 13 : 1000957659
Total Pages : 255 pages
Book Rating : 4.55/5 ( download)

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Book Synopsis SARS-CoV2 (COVID-19) Pandemic Control and Prevention by : Laurens Holmes, Jr.

Download or read book SARS-CoV2 (COVID-19) Pandemic Control and Prevention written by Laurens Holmes, Jr. and published by Taylor & Francis. This book was released on 2023-09-29 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive text to provide not only a detailed explanation of how the SARS-CoV2 (COVID-19) virus is spread within human populations, but also an epidemiological analysis and interpretation of viral pandemics to enable better measures for prevention and control. Providing an introduction to the physiology of both the human immune system and the SARS-CoV2 virus, specifically the virus’s replicative potential and our own vulnerability, the book offers an in-depth understanding of how the pandemic evolved. It also highlights the aberrant epigenomic mechanistic process in pathogenic microbe’s replication and survival, implying gene and environment interaction that affected different populations. Citing a range of environmental conditions, from structural and systemic racism to malnutrition and low-socioeconomic status, the book examines how these factors exacerbated existing health disparities, resulting in a disproportionate burden of morbidity and mortality on certain social groups. Also providing invaluable guidance on how future iterations of this pandemic may be better prevented and controlled, this will be a defining book for students, researchers and professionals within Public Health and Clinical Medicine to better understand the SARS-CoV2 (COVID-19) virus, and how to protect the most vulnerable social groups.

Drug Repositioning

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Publisher : John Wiley & Sons
ISBN 13 : 0470878274
Total Pages : 499 pages
Book Rating : 4.79/5 ( download)

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Book Synopsis Drug Repositioning by : Michael J. Barratt

Download or read book Drug Repositioning written by Michael J. Barratt and published by John Wiley & Sons. This book was released on 2012-05-29 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs. Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.