Concepts And Case Studies In Chemical Biology

Author : Herbert Waldmann
Publisher : John Wiley & Sons
ISBN 13 : 3527336117
Total Pages : 468 pages
Book Rating : 4.11/5 ( download)

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Download or read book Concepts and Case Studies in Chemical Biology written by Herbert Waldmann and published by John Wiley & Sons. This book was released on 2014-10-06 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retaining the proven didactic concept of the successful "Chemical Biology - Learning through Case Studies", this sequel features 27 new case studies, reflecting the rapid growth in this interdisciplinary topic over the past few years. Edited by two of the world's leading researchers in the field, this textbook introduces students and researchers to the modern approaches in chemical biology, as well as important results, and the techniques and methods applied. Each chapter presents a different biological problem taken from everyday lab work, elucidated by an international team of renowned scientists. With its broad coverage, this is a valuable source of information for students, graduate students, and researchers working on the borderline between chemistry, biology, and biochemistry.

Author : Felicia A Etzkorn
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160160
Total Pages : 468 pages
Book Rating : 4.65/5 ( download)

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Download or read book Green Chemistry written by Felicia A Etzkorn and published by Royal Society of Chemistry. This book was released on 2019-12-03 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green chemistry as a discipline is gaining increasing attention globally, with environmentally conscious students keen to learn how they can contribute to a safer and more sustainable world. Many universities now offer courses or modules specifically on green chemistry – Green Chemistry: Principles and Case Studies is an essential learning resource for those interested in mastering the subject. Providing a comprehensive overview of the concepts of green chemistry this book engages students with a thorough understanding of what we mean by green chemistry and how it can be put into practice. Structured around the well-known 12 Principles, and firmly grounded in real-world applications and case-studies, this book shows how green chemistry is already being put into practice and prepare them to think about how they can be incorporated into their own work. Targeted at advanced undergraduate and first-year graduate students with a background in general and organic chemistry, it is a useful resource both for students and for teachers looking to develop new courses.

Author : Siddhartha Roy
Publisher : Academic Press
ISBN 13 : 0128176458
Total Pages : 352 pages
Book Rating : 4.50/5 ( download)

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Download or read book Chemical Biology of the Genome written by Siddhartha Roy and published by Academic Press. This book was released on 2021-05-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biology of the Genome provides a comprehensive overview of essential concepts and principles of genomic and epigenomics dynamics as explored through the lens of chemical biology. Key examples and case studies illustrate chemical biology methods for study and analysis of the genome and epigenome, with an emphasis on relevance to physiological and pathophysiological processes and drug discovery. Authors and international leaders in biochemical studies of the genome, Drs. Siddhartha Roy and Tapas Kundu, adopt an integrated, interdisciplinary approach throughout, demonstrating how fast evolving chemical and mass-scale sequencing tools are increasingly used to interpret biochemical processes of the genome. Later sections discuss chemical modifications of the genome, DNA sequence recognition by proteins and gene regulation, GWAS and EpiGWAS studies, 3D architecture of the genome, and functional genome architecture. In-depth, discovery focused chapters examine intervention in gene networks using SiRNA/ShRNA, miRNA, and anti-miR, small molecule modulation of iPS, drug resistance pathways altered DNA methylation as drug targets, anti-miR as therapeutics, and nanodelivery of drugs. Offers an interdisciplinary discussion of the chemical biology of the genome and epigenome, employing illustrative case studies in both physiological and pathophysiological contexts Supports researchers in employing chemical and mass-scale sequencing approaches to interpret genomic and epigenomic dynamics Highlights innovative pathways and molecular targets for new disease study and drug discovery

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.71/5 ( download)

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Download or read book Chemical Biology written by and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Xianhai Huang
Publisher : John Wiley & Sons
ISBN 13 : 1118219678
Total Pages : 488 pages
Book Rating : 4.76/5 ( download)

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Download or read book Case Studies in Modern Drug Discovery and Development written by Xianhai Huang and published by John Wiley & Sons. This book was released on 2012-04-19 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies. Case Studies in Modern Drug Discovery and Development begins with an introductory chapter that puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities. Next, there are fourteen detailed case studies, examining: All phases of drug discovery and development from initial idea to commercialization Some of today's most important and life-saving medications Drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies Examples of prodrugs and inhaled drugs Reasons why certain drugs failed to advance to market despite major research investments Each chapter ends with a list of references leading to the primary literature. There are also plenty of tables and illustrations to help readers fully understand key concepts, processes, and technologies. Improving the success rate of the drug discovery and development process is paramount to the pharmaceutical industry. With this book as their guide, readers can learn from both successful and unsuccessful efforts in order to apply tested and proven science and technologies that increase the probability of success for new drug discovery and development projects.

Author : Jurriaan Huskens
Publisher : John Wiley & Sons
ISBN 13 : 1119143462
Total Pages : 434 pages
Book Rating : 4.68/5 ( download)

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Download or read book Multivalency written by Jurriaan Huskens and published by John Wiley & Sons. This book was released on 2018-02-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.

Author : Dean R. Appling
Publisher : What's New in Biochemistry
ISBN 13 : 9780134804668
Total Pages : 912 pages
Book Rating : 4.6X/5 ( download)

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Download or read book Biochemistry written by Dean R. Appling and published by What's New in Biochemistry. This book was released on 2018-01-15 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: NOTE: Before purchasing, check with your instructor to ensure you select the correct ISBN. Several versions of the MyLab(tm)and Mastering(tm) platforms exist for each title, and registrations are not transferable. To register for and use MyLab or Mastering, you may also need a Course ID, which your instructor will provide. Used books, rentals, and purchases made outside of Pearson If purchasing or renting from companies other than Pearson, the access codes for the Mastering platform may not be included, may be incorrect, or may be previously redeemed. Check with the seller before completing your purchase. For courses in biochemistry. This package includes Mastering Chemistry. Engage students in biochemistry visually and through real-world applications Biochemistry: Concepts and Connections engages students with a unique approach to visualization, synthesis of complex topics, and connections to the real world. The author team builds quantitative reasoning skills and provides students with a rich, chemical perspective on biological processes. The text emphasizes fundamental concepts and connections, showing how biochemistry relates to practical applications in medicine, agricultural sciences, environmental sciences, and forensics. The newly revised 2nd Edition integrates even more robust biochemistry-specific content in Mastering(tm) Chemistry, creating an interactive experience for today's students. New Threshold Concept Tutorials help students master the most challenging and critical ideas in biochemistry, while Interactive Case Studies connect course material to the real world by having students explore actual scientific data from primary literature. The 2nd Edition provides a seamlessly integrated learning experience via text, Mastering Chemistry, and an interactive Pearson eText. Personalize learning with Mastering Chemistry Mastering(tm) is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools developed to engage students and emulate the office-hour experience, Mastering personalizes learning and often improves results for each student. Students can further master concepts after class through traditional and adaptive homework assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess student understanding and misconceptions. 013480466X / 9780134804668 Biochemistry: Concepts and Connections Plus Mastering Chemistry with Pearson eText -- Access Card Package Package consists of: 0134641620 / 9780134641621 Biochemistry: Concepts and Connections 013474716X / 9780134747163 Mastering Chemistry with Pearson eText -- ValuePack Access Card -- for Biochemistry: Concepts and Connections

Author : Marcus T. Scotti
Publisher : Springer Nature
ISBN 13 : 3030958957
Total Pages : 266 pages
Book Rating : 4.54/5 ( download)

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Download or read book Drug Target Selection and Validation written by Marcus T. Scotti and published by Springer Nature. This book was released on 2022-05-17 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.

Author : Bruno Pignataro
Publisher : John Wiley & Sons
ISBN 13 : 9783527630523
Total Pages : 358 pages
Book Rating : 4.2X/5 ( download)

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Download or read book Ideas in Chemistry and Molecular Sciences written by Bruno Pignataro and published by John Wiley & Sons. This book was released on 2010-04-16 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideas in Chemistry and Molecular Sciences gives an account of the most recent results of research in life sciences in Europe based on a selection of leading young scientists participating in the 2008 European Young Chemists Award competition. In addition to this, the authors provide the state of the art of their field of research and the perspective or preview of future directions.

Author : Raymond S.H. Yang
Publisher : Elsevier
ISBN 13 : 1483289400
Total Pages : 745 pages
Book Rating : 4.03/5 ( download)

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Download or read book Toxicology of Chemical Mixtures written by Raymond S.H. Yang and published by Elsevier. This book was released on 2013-10-22 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although toxicologic studies in the laboratory often focus on a single chemical, in the larger world, mixtures of chemicals are routinely encountered. Toxicology of Chemical Mixtures examines the mechanisms of interactions and health effects stemming from chemical mixtures in the environment. Toxicologists, pharmacologists, environmental scientists, and professionals involved in environmental clean-ups will benefit from its content. Emphasis is on low-level, long-term exposure. Some of the issues addressed include Target organ toxicities in response to chemical mixture exposures Risk assessment and experimental approaches Case studies and special pollution problems Special pollution problems