Computational And Experimental Studies In Alzheimers Disease

Author : Kunal Bhattacharya
Publisher : CRC Press
ISBN 13 : 1003857345
Total Pages : 210 pages
Book Rating : 4.41/5 ( download)

DOWNLOAD NOW!

Download or read book Computational and Experimental Studies in Alzheimer's Disease written by Kunal Bhattacharya and published by CRC Press. This book was released on 2024-03-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book compiles the recent advances in computational and experimental modelling to screen and manage Alzheimer’s disease. It covers basic etiopathology and various in vitro and in vivo strategies of disease intervention. The book discusses how computer-aided drug design approaches reduce costs and increase biological test efficiency. It reviews the screening for anti-Alzheimer drugs and biomarker analysis of disease inhibitors. The book also explores mechanistic aspects of neurodegeneration and the use of natural products as therapeutics for Alzheimer’s disease. Key features: Elaborates on the computational modelling of protein target inhibitors as anti-Alzheimer’s agents Explains the role of phytomolecules and natural products in Alzheimer’s therapy Reviews preclinical ways to assess drugs focusing on Alzheimer’s disease Covers biomarker analysis for Alzheimer’s disease Discusses the onset and progression of Alzheimer’s disease The book is meant for professionals, researchers, and students of neuroscience, psychology, and computational neurosciences.

Author : Bayu Tri Murti
Publisher :
ISBN 13 :
Total Pages : 466 pages
Book Rating : 4.56/5 ( download)

DOWNLOAD NOW!

Download or read book Experimental and Computational Studies on Sensing of DNA Damage in Alzheimer's Disease written by Bayu Tri Murti and published by . This book was released on 2017 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Don Kulasiri
Publisher : Wspc (Europe)
ISBN 13 : 9781800610118
Total Pages : 480 pages
Book Rating : 4.14/5 ( download)

DOWNLOAD NOW!

Download or read book Alzheimer's Disease: Biology, Biophysics and Computational Models written by Don Kulasiri and published by Wspc (Europe). This book was released on 2022-01-06 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD) is the leading cause of dementia and, unfortunately, remains incurable. The social, emotional and financial implications of AD are immeasurable, and about 47 million people worldwide are affected by AD or other forms of dementia. As lifespans are improved by healthcare systems worldwide, age-associated neurodegenerative diseases are imposing an increasing challenge to science. It is becoming imperative for us to understand the causes of these diseases, AD in particular, at molecular and cellular levels. Starting with the broader picture from a biological perspective, this book takes the reader through fascinating dynamics within and outside of neurons in the brain. Alzheimer's Disease: Biology, Biophysics and Computational Models helps the reader to understand AD from mechanistic and biochemical perspectives at intra- and inter-cellular levels. It focuses on biochemical pathways and modeling associated with AD. Some of the recent research on biophysics and computational models related to AD are explained using context-driven computational and mathematical modeling and essential biology is discussed to understand the modeling research.

Author : National Academies of Sciences Engineering and Medicine
Publisher :
ISBN 13 : 9780309495035
Total Pages : pages
Book Rating : 4.32/5 ( download)

DOWNLOAD NOW!

Download or read book Reducing the Impact of Dementia in America written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-04-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.

Author : Thimmaiah Govindaraju
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162740
Total Pages : 695 pages
Book Rating : 4.49/5 ( download)

DOWNLOAD NOW!

Download or read book Alzheimer's Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.

Author : Erik D. Roberson
Publisher : Humana Press
ISBN 13 : 9781607617433
Total Pages : 0 pages
Book Rating : 4.39/5 ( download)

DOWNLOAD NOW!

Download or read book Alzheimer's Disease and Frontotemporal Dementia written by Erik D. Roberson and published by Humana Press. This book was released on 2010-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease and frontotemporal dementia, two of the most prevalent neurodegenerative diseases, are dreaded disorders that attack the neural networks underlying memory and personality, systems that make us who we are. Major breakthroughs in recent years have spurred new research approaches to these conditions. In Alzheimer's Disease and Frontotemporal Dementia: Methods and Protocols, expert investigators bring together the many divergent areas of expertise used to study these diseases, including behavior, electrophysiology, confocal microscopy, and hardcore biochemistry. Beginning with an overview of the two diseases and contemporary research on them, the book continues with specialized protocols for working with amyloid-β peptide, tau, and apolipoprotein E as well as experimental systems for studying AD and FTD, including cell and animal models, and outcome measures that can be used to assess neuronal function in these systems. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Alzheimer's Disease and Frontotemporal Dementia: Methods and Protocols serves as an ideal guide for all scientists pursuing the cause and cure of these widespread and nightmarishly debilitating disorders.

Author : Mohammad Amjad Kamal
Publisher : Frontiers Media SA
ISBN 13 : 2832547737
Total Pages : 202 pages
Book Rating : 4.31/5 ( download)

DOWNLOAD NOW!

Download or read book The Alzheimer's Disease Challenge, Volume II written by Mohammad Amjad Kamal and published by Frontiers Media SA. This book was released on 2024-04-15 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the success of Volume I of this Research Topic, we are pleased to announce the launch of Volume II: “The Alzheimer's Disease Challenge”. The repeated failure of clinical trials on the amyloid-based medications and the pessimistic calculations of Alzheimer's disease cost burden for the next few decades present a severe challenge to humankind with severe social implications. In recent years, several alternative diagnostic and treatment procedures have been presented to treat and manage Alzheimer’s disease as it has been nearly impossible to suggest a holistic solution. Several revelations in human biology have highlighted the multiparametric character of the disease. Besides the amyloid aggregation and neurofibrillary tangles that result in Aβ toxicity and tau phosphorylation, processes such as Gene Mutations, Proteins Misfolding, Brain Biochemical and Histopathological Changes, Behavioral Changes, Nutrition and Metabolism Alterations, and Autonomic Dysfunctions due to Central Nervous System dysregulations are common signs and probably early diagnostic biomarkers in most of the Alzheimer's classification categories.

Author : Mauricio Reyes
Publisher : Springer Nature
ISBN 13 : 3030874443
Total Pages : 138 pages
Book Rating : 4.45/5 ( download)

DOWNLOAD NOW!

Download or read book Interpretability of Machine Intelligence in Medical Image Computing, and Topological Data Analysis and Its Applications for Medical Data written by Mauricio Reyes and published by Springer Nature. This book was released on 2021-09-21 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed joint proceedings of the 4th International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2020, and the First International Workshop on Topological Data Analysis and Its Applications for Medical Data, TDA4MedicalData 2021, held on September 27, 2021, in conjunction with the 24th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2021. The 7 full papers presented at iMIMIC 2021 and 5 full papers held at TDA4MedicalData 2021 were carefully reviewed and selected from 12 submissions each. The iMIMIC papers focus on introducing the challenges and opportunities related to the topic of interpretability of machine learning systems in the context of medical imaging and computer assisted intervention. TDA4MedicalData is focusing on using TDA techniques to enhance the performance, generalizability, efficiency, and explainability of the current methods applied to medical data.

Author : Michael J. Wenger
Publisher : Psychology Press
ISBN 13 : 1135603359
Total Pages : 360 pages
Book Rating : 4.59/5 ( download)

DOWNLOAD NOW!

Download or read book Statistical and Process Models for Cognitive Neuroscience and Aging written by Michael J. Wenger and published by Psychology Press. This book was released on 2007-01-30 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses methodological techniques for researching cognitive impairment, Alzheimer's disease, the biophysics and structure of the nervous system, the physiology of memory, and the analysis of EEG data. Intended for researchers in cognitive, be

Author : Melvin L. Kohn
Publisher : Greenwood
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.91/5 ( download)

DOWNLOAD NOW!

Download or read book Work and Personality written by Melvin L. Kohn and published by Greenwood. This book was released on 1983 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: