Community Series In Novel Biomarkers For Predicting Response To Cancer Immunotherapy Volume Ii

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832541933
Total Pages : 261 pages
Book Rating : 4.37/5 ( download)

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Download or read book Community Series in Novel Biomarkers for Predicting Response to Cancer Immunotherapy, volume II written by and published by Frontiers Media SA. This book was released on 2024-01-10 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is the second volume of the “Community Series in Novel Biomarkers for Predicting Response to Cancer Immunotherapy". Please see Volume I here. Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutation burden (TMB), immune genomic characteristics, and tumor infiltrating lymphocytes (TILs). However, none of them have sufficient evidence to be a stratification factor. Moreover, as the combined strategies for effective cancer immunotherapy had been developed in multiple tumors, such as Immunotherapy combined with chemotherapy, radiotherapy, targeted therapy and anti-angiogenesis therapy. Therefore, the development of novel biomarkers endowed with high sensitivity, specificity and accuracy able to identify which patients may truly benefit from the treatment with cancer immunotherapy would allow to refine the therapeutic selection and to better tailor the treatment strategy. This research topic aims to focus on the advances in the discoveries of novel biomarkers for predicting response to cancer immunotherapy in various tumors. We welcome the submission of original research and review articles that include biomarkers in clinical study and applications, as well as technologies or discoveries in experimental approaches.

Author : Jinghua Pan
Publisher : Frontiers Media SA
ISBN 13 : 2832525490
Total Pages : 493 pages
Book Rating : 4.94/5 ( download)

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Download or read book Novel Biomarkers for Predicting Response to Cancer Immunotherapy written by Jinghua Pan and published by Frontiers Media SA. This book was released on 2023-07-11 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutation burden (TMB), immune genomic characteristics, and tumor infiltrating lymphocytes (TILs). However, none of them have sufficient evidence to be a stratification factor. Moreover, as the combined strategies for effective cancer immunotherapy had been developed in multiple tumors, such as Immunotherapy combined with chemotherapy, radiotherapy, targeted therapy and anti-angiogenesis therapy. Therefore, the development of novel biomarkers endowed with high sensitivity, specificity and accuracy able to identify which patients may truly benefit from the treatment with cancer immunotherapy would allow to refine the therapeutic selection and to better tailor the treatment strategy.

Author : Xuelei Ma
Publisher : Frontiers Media SA
ISBN 13 : 283253015X
Total Pages : 264 pages
Book Rating : 4.53/5 ( download)

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Download or read book Community series in immunotherapy with checkpoint inhibitors for non-small cell lung cancer, colon cancer and esophageal cancer, volume II written by Xuelei Ma and published by Frontiers Media SA. This book was released on 2023-07-27 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Xiangpeng Dai
Publisher : Frontiers Media SA
ISBN 13 : 2832536778
Total Pages : 147 pages
Book Rating : 4.73/5 ( download)

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Download or read book Community Series in Post-Translational Modifications of Proteins in Cancer Immunity and Immunotherapy, Volume II written by Xiangpeng Dai and published by Frontiers Media SA. This book was released on 2023-10-25 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Xiao Liang
Publisher : Frontiers Media SA
ISBN 13 : 2832522467
Total Pages : 191 pages
Book Rating : 4.62/5 ( download)

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Download or read book Community series in novel insights into immunotherapy targeting tumor microenvironment in ovarian cancer, volume I written by Xiao Liang and published by Frontiers Media SA. This book was released on with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Jian Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2832532276
Total Pages : 477 pages
Book Rating : 4.70/5 ( download)

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Download or read book Community series in combining chemo/radio therapy and immunotherapy for cancers— perfect mix of old and new, volume II written by Jian Zhang and published by Frontiers Media SA. This book was released on 2023-08-23 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Huanfa Yi
Publisher : Frontiers Media SA
ISBN 13 : 2832529542
Total Pages : 247 pages
Book Rating : 4.46/5 ( download)

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Download or read book Community Series in Manipulating the Immunological Tumor Microenvironment - Volume II written by Huanfa Yi and published by Frontiers Media SA. This book was released on 2023-07-17 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Vered Stearns
Publisher : Springer
ISBN 13 : 9783319229089
Total Pages : 0 pages
Book Rating : 4.87/5 ( download)

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Download or read book Novel Biomarkers in the Continuum of Breast Cancer written by Vered Stearns and published by Springer. This book was released on 2016-03-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer. The volume covers topics related to breast cancer risk and prevention, prediction of response to today’s standard therapies, and markers capable of influencing treatment decisions in the near future. Chapter authors combine their wide-ranging expertise to review the current status of the biomarker and to offer their individual perspectives on how biomarkers may be used in future treatments and research. Breast cancer continues to be the most common malignancy diagnosed in women in the Western world. While there are multiple treatment approaches for breast cancer, today more than ever we recognize that each tumor is unique. The challenge ahead is to consider how to best use validated and novel biomarkers to select the most appropriate treatment(s) for individual patients.

Author : Xi Cheng
Publisher : Frontiers Media SA
ISBN 13 : 2832540821
Total Pages : 213 pages
Book Rating : 4.24/5 ( download)

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Download or read book Community Series in the Role of Angiogenesis and Immune Response in Tumor Microenvironment of Solid Tumor, volume II written by Xi Cheng and published by Frontiers Media SA. This book was released on 2023-12-13 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is the second volume of the “Community Series in the Role of Angiogenesis and Immune Response in Tumor Microenvironment of Solid Tumor". Please Volume I here. The microenvironment of tumors is consisted of the tumor stroma, proliferating tumor cells, infiltrating inflammatory cells, blood vessels, and various associated tissue cells. The pre-metastatic niche (PRN) is described as supportive and receptive, which undergoes cellular and molecular changes to form the fertile “soil” or metastatic-designated sites for metastatic tumor cell “seed” colonization. Thus, the PRN supports promoting tumor metastasis and tumor settlement in distant organs. The infiltration of the immune cells and the formation of blood vessels from the pre-metastatic sites are critical for the tumor microenvironment. Typically, the angiogenic factor is strongly associated with the inflammatory response during the development of tumors. Additionally, the immunoediting processes are essentially devoted to promoting angiogenesis and modulating the innate and specific immune responses.

Author : Ping Zheng
Publisher : Frontiers Media SA
ISBN 13 : 2832541232
Total Pages : 383 pages
Book Rating : 4.34/5 ( download)

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Download or read book Community series in unveiling the tumor microenvironment by machine learning to develop new immunotherapeutic strategies, volume II written by Ping Zheng and published by Frontiers Media SA. This book was released on 2024-02-06 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: