Co Crystals

Author : Johan Wouters
Publisher : Royal Society of Chemistry
ISBN 13 : 1849733503
Total Pages : 406 pages
Book Rating : 4.02/5 ( download)

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Download or read book Pharmaceutical Salts and Co-crystals written by Johan Wouters and published by Royal Society of Chemistry. This book was released on 2011-11-04 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: From crystal structure prediction to totally empirical screening, the quest for new crystal forms has become one of the most challenging issues in the solid state science and particularly in the pharmaceutical world. In this context, multi-component crystalline materials like co-crystals have received renewed interest as they offer the prospect of optimized physical properties. As illustrated in this first book_ entirely dedicated to this emerging class of pharmaceutical compounds_ the outcome of such endeavours into crystal engineering have demonstrated clear impacts on production, marketing and intellectual property protection of active pharmaceutical ingredients (APIs). Indeed, co-crystallization influences relevant physico-chemical parameters (such as solubility, dissolution rate, chemical stability, melting point, hygroscopicity, à) and often offers solids with properties superior to those of the free drug. Combining both reports of the latest research and comprehensive overviews of basic principles, with contributions from selected experts in both academia and industry, this unique book is an essential reference, ideal for pharmaceutical development scientists and graduate students in pharmaceutical science.

Author : Christer B Aakeröy
Publisher : Royal Society of Chemistry
ISBN 13 : 1788011155
Total Pages : 342 pages
Book Rating : 4.50/5 ( download)

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Download or read book Co-crystals written by Christer B Aakeröy and published by Royal Society of Chemistry. This book was released on 2018-07-16 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multi-component crystalline systems or co-crystals have received tremendous attention from academia and industry alike in the past decade. Applications of co-crystals are varied and are likely to positively impact a wide range of industries dealing with molecular solids. Co-crystallization has been used to improve the properties and performance of materials from pharmaceuticals to energetic materials, as well as for separation of compounds. This book combines co-crystal applications of commercial and practical interest from diverse fields in to a single volume. It also examines effective structural design of co-crystals, and provides insights into practical synthesis and characterization techniques. Providing a useful resource for postgraduate students new to applied co-crystal research and crystal engineering, it will also be of interest to established researchers in academia or industry.

Author : Edward Tiekink
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110464950
Total Pages : 362 pages
Book Rating : 4.55/5 ( download)

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Download or read book Multi-Component Crystals written by Edward Tiekink and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-11-20 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, contributions covering the theoretical and practical aspects of multicomponent crystals provide a timely and contemporary overview of the state-of-the art of this vital aspect of crystal engineering/materials science. With a solid foundation in fundamentals, multi-component crystals can be formed, for example, to enhance pharmaceutical properties of drugs, for the specific control of optical responses to external stimuli and to assemble molecules to allow chemical reactions that are generally intractable following conventional methods. Contents Pharmaceutical co-crystals: crystal engineering and applications Pharmaceutical multi-component crystals: improving the efficacy of anti-tuberculous agents Qualitative and quantitative crystal engineering of multi-functional co-crystals Control of photochromism in N-salicylideneaniline by crystal engineering Quinoline derivatives for multi-component crystals: principles and applications N-oxides in multi-component crystals and in bottom-up synthesis and applications Multi-component crystals and non-ambient conditions Co-crystals for solid-state reactivity and thermal expansion Solution co-crystallisation and its applications The salt-co-crystal continuum in halogen-bonded systems Large horizontal displacements of benzene-benzene stacking interactions in co-crystals Simultaneous halogen and hydrogen bonding to carbonyl and thiocarbonylfunctionality Crystal chemistry of the isomeric N,N’-bis(pyridin-n-ylmethyl)-ethanediamides, n = 2, 3 or 4 Solute・solvent interactions mediated by main group element (lone-pair)・・・π(aryl) interactions

Author : Johan Wouters
Publisher : Royal Society of Chemistry
ISBN 13 : 1849731586
Total Pages : 407 pages
Book Rating : 4.84/5 ( download)

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Download or read book Pharmaceutical Salts and Co-crystals written by Johan Wouters and published by Royal Society of Chemistry. This book was released on 2011 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the hot topic of pharmaceutical salts and co-crystals focusing on the following essential aspects: an overview of fundamental aspects on salts and co-crystals, racemic resolution via diastereomer separation, optimization of relevant physico-chemical parameters, and strengthening of intellectual property.

Author : Christer B Aakeröy
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014898
Total Pages : 354 pages
Book Rating : 4.92/5 ( download)

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Download or read book Co-crystals written by Christer B Aakeröy and published by Royal Society of Chemistry. This book was released on 2018-07-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multi-component crystalline systems or co-crystals have received tremendous attention from academia and industry alike in the past decade. Applications of co-crystals are varied and are likely to positively impact a wide range of industries dealing with molecular solids. Co-crystallization has been used to improve the properties and performance of materials from pharmaceuticals to energetic materials, as well as for separation of compounds. This book combines co-crystal applications of commercial and practical interest from diverse fields in to a single volume. It also examines effective structural design of co-crystals, and provides insights into practical synthesis and characterization techniques. Providing a useful resource for postgraduate students new to applied co-crystal research and crystal engineering, it will also be of interest to established researchers in academia or industry.

Author :
Publisher : Academic Press
ISBN 13 : 0080921876
Total Pages : 585 pages
Book Rating : 4.77/5 ( download)

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Download or read book Annual Reports in Medicinal Chemistry written by and published by Academic Press. This book was released on 2008-12-17 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Covers findings related to cardiovascular, inflammation, and pulmonary diseases Examines issues in oncology, from mTor inhibitors to drug targets Incorporates up-to-date information on drug design and discovery, including delivery to market

Author : Alison Lewis
Publisher : IOS Press
ISBN 13 : 1586037900
Total Pages : 284 pages
Book Rating : 4.01/5 ( download)

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Download or read book BIWIC 2007 written by Alison Lewis and published by IOS Press. This book was released on 2007 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of crystallization holds many challenges, with the physical and chemical complexity of the crystallization process being core to the dynamic nature of the field. Exciting advances are achieved in the areas of nanoparticle formation, product and particle design and methods of particle characterization.

Author : Juan J Novoa
Publisher : Royal Society of Chemistry
ISBN 13 : 1788013336
Total Pages : 782 pages
Book Rating : 4.38/5 ( download)

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Download or read book Intermolecular Interactions in Crystals written by Juan J Novoa and published by Royal Society of Chemistry. This book was released on 2017-10-25 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of crystal engineering concerns the design and synthesis of molecular crystals with desired properties. This requires an in-depth understanding of the intermolecular interactions within crystal structures. This new book brings together the latest information and theories about intermolecular bonding, providing an introductory text for graduates. The book is divided into three parts. The first part covers the nature, physical meaning and methods for identification and analysis of intermolecular bonds. The second part explains the different types of bond known to occur in molecular crystals, with each chapter written by a specialist in that specific bond type. The final part discusses the cooperativity effects of different bond types present in one solid. This comprehensive textbook will provide a valuable resource for all students and researchers in the field of crystallography, materials science and supramolecular chemistry.

Author : Anna V. Vologzhanina
Publisher : MDPI
ISBN 13 : 3039361708
Total Pages : 144 pages
Book Rating : 4.00/5 ( download)

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Download or read book Chemical Bonding in Crystals and Their Properties written by Anna V. Vologzhanina and published by MDPI. This book was released on 2020-06-16 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unravelling an intricate network of interatomic interactions and their relations to different behaviors of chemical compounds is key to the successful design of new materials for both existing and novel applications, from medicine to innovative concepts of molecular electronics and spintronics. X-ray crystallography has proven to be very helpful in addressing many important chemical problems in modern materials science and biosciences. Intertwined with computational techniques, it provides insights into the nature of chemical bonding and the physicochemical properties (including optical, magnetic, electrical, mechanical, and others) of crystalline materials, otherwise accessible by experimental techniques that are not so readily available to chemists. In addition to the advanced approaches in charge density analysis made possible by X-ray diffraction, the information collected over the years through this technique (which is easily mined from huge databases) has tremendous use in the design of new materials for medicine, gas storage, and separation applications as well as for electronic devices. This Special Issue contains two reviews and five articles that cover very different aspects of ‘composition–structure’ and ‘structure–property’ relations identified by X-ray diffraction and complementary techniques (from conventional IR and Raman spectroscopies to cutting-edge quantum chemical calculations) and their use in crystal engineering and materials science.

Author : Edward R. T. Tiekink
Publisher : John Wiley & Sons
ISBN 13 : 0470022590
Total Pages : 346 pages
Book Rating : 4.97/5 ( download)

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Download or read book Frontiers in Crystal Engineering written by Edward R. T. Tiekink and published by John Wiley & Sons. This book was released on 2006-05-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crystal engineering - where the myriad of intermolecular forces operating in the solid-state are employed to design new nano- and functional materials - is a key new technology with implications for catalysis, pharmaceuticals, synthesis and materials science. Frontiers in Crystal Engineering gathers personal perspectives, from international specialists working in molecular aspects of crystal engineering, on the practical and theoretical challenges of the discipline, and future prospects. These demonstrate the approaches that are being used to tackle the problems associated with the complexity, design and functionality of crystalline molecular solids. Topics include * how intermolecular forces direct and sustain crystal structures * functional engineering and design elements * coordination polymers and network structures * applications in green and pharmaceutical chemistry Frontiers in Crystal Engineering is a useful guide to this exciting new discipline for both entrants to the field as well as established practitioners, and for those working in crystallography, medicinal and pharmaceutical sciences, solid-state chemistry, and materials and nanotechnology.