Clinical Investigation of the Microcirculation

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Author :
Publisher : Springer
ISBN 13 : 9781461294344
Total Pages : 224 pages
Book Rating : 4.47/5 ( download)

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Book Synopsis Clinical Investigation of the Microcirculation by : John E. Tooke

Download or read book Clinical Investigation of the Microcirculation written by John E. Tooke and published by Springer. This book was released on 2011-09-27 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1628 William Harvey published his discovery of the existence of the microcirculation which he deduced from careful anatomical and physiological study. Thirty-three years later, Malpighi confirmed the presence of capillaries through direct microscopical observation. Subsequent scientific advance has been slow, and in view of the fact that microvascular in the genesis and expression of many pathophysiology may be implicated diseases, our know ledge of human microvascular function is surprisingly limited. This ignorance attests to the difficulty of studying something that is both minute and inaccessible without disturbing the quantity that is being measured. In the last fifteen years, however, direct techniques have been developed for studying human microvascular pressure, flow and permeability. These methods have provided new insights into human microvascular function in health and disease. At the same time there has been a steady growth of new indirect techniques based on a w ide range of physical principles that reflect some or other aspect of microvascular function.

Clinically Applied Microcirculation Research

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Author :
Publisher : Routledge
ISBN 13 : 0429523432
Total Pages : 513 pages
Book Rating : 4.34/5 ( download)

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Book Synopsis Clinically Applied Microcirculation Research by : John Barker

Download or read book Clinically Applied Microcirculation Research written by John Barker and published by Routledge. This book was released on 2019-06-04 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995: Clinically Applied Microcirculation Research combines state-of-the-art microcirculation technology with present and potential applications in clinical medicine. This comprehensive guide unites the expertise of clinicians and basic researchers from around the world. Many of the chapters are authored by scientist/physician teams. The book provides a broad overview of how microcirculation is involved in clinical research. This is also a valuable reference source for both the history of and latest developments in microcirculation research.

Inflammation and the Microcirculation

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041656
Total Pages : 99 pages
Book Rating : 4.57/5 ( download)

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Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger

Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Basic and Clinical Understanding of Microcirculation

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789855519
Total Pages : 168 pages
Book Rating : 4.17/5 ( download)

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Book Synopsis Basic and Clinical Understanding of Microcirculation by : Kaneez Fatima Shad

Download or read book Basic and Clinical Understanding of Microcirculation written by Kaneez Fatima Shad and published by BoD – Books on Demand. This book was released on 2020-07-22 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microcirculation is key to providing enough nutrition and oxygen from head to toe. This is possible only through an extensive network of blood vessels spread around the body. Effect of microcirculation abnormalities stretch beyond one’s comprehension. The effects could be felt at any age, from the foetal life to the adulthood. The chapters present in this book describe how these abnormalities could lead to diseases such as atherosclerosis, thrombosis, diabetes, hypertension. Disorders of microcirculation could be related to the structural and/or functional damage to the inner lining of the blood vessels. Early identification of these disorders could benefit many ailments including cardiovascular and cerebrovascular diseases such as heart attack and stroke.

Microcirculation

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Publisher : Elsevier
ISBN 13 : 0323155499
Total Pages : 334 pages
Book Rating : 4.96/5 ( download)

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Book Synopsis Microcirculation by : Richard Effros

Download or read book Microcirculation written by Richard Effros and published by Elsevier. This book was released on 2012-12-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microcirculation: Current Physiologic, Medical, and Surgical Concepts is based primarily on a course and a series of lectures presented at a congress on microcirculation held at the University of California in August 1979. The book gives an overview of the concepts regarding the structure and properties of small vessels, a topic mostly read only in specialized journals. The primary focus of the text is on the function and dysfunction of small blood vessels. Three major parts comprise the text. Part I discusses the morphology, physiology, and pharmacology of circulation, and Part II presents the dynamics or role of the microcirculation in the study of diabetes. Finally, Part III discusses also the role of microcirculation in disease states, particularly hemoconcentration. The book will provide much information to researchers and students in the fields of biology, medicine, physiology, and pharmacology.

The Microcirculation in Clinical Medicine

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Publisher :
ISBN 13 :
Total Pages : 354 pages
Book Rating : 4.68/5 ( download)

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Book Synopsis The Microcirculation in Clinical Medicine by : Roe Wells

Download or read book The Microcirculation in Clinical Medicine written by Roe Wells and published by . This book was released on 1973 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Investigation of the Microcirculation

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461323355
Total Pages : 224 pages
Book Rating : 4.58/5 ( download)

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Book Synopsis Clinical Investigation of the Microcirculation by : John E. Tooke

Download or read book Clinical Investigation of the Microcirculation written by John E. Tooke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1628 William Harvey published his discovery of the existence of the microcirculation which he deduced from careful anatomical and physiological study. Thirty-three years later, Malpighi confirmed the presence of capillaries through direct microscopical observation. Subsequent scientific advance has been slow, and in view of the fact that microvascular in the genesis and expression of many pathophysiology may be implicated diseases, our know ledge of human microvascular function is surprisingly limited. This ignorance attests to the difficulty of studying something that is both minute and inaccessible without disturbing the quantity that is being measured. In the last fifteen years, however, direct techniques have been developed for studying human microvascular pressure, flow and permeability. These methods have provided new insights into human microvascular function in health and disease. At the same time there has been a steady growth of new indirect techniques based on a w ide range of physical principles that reflect some or other aspect of microvascular function.

Clinical Hemorheology

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Publisher : Springer Science & Business Media
ISBN 13 : 9400942850
Total Pages : 556 pages
Book Rating : 4.51/5 ( download)

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Book Synopsis Clinical Hemorheology by : S. Chien

Download or read book Clinical Hemorheology written by S. Chien and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: The task the editors have set themselves is to survey the field of clinical hemorheology from basic principles to up-to-date research. It is only in a new science like this that it is possible to span the whole field in a book of this size. Hemorheology, as a new approach to the study and management of a wide range of circulatory diseases, is now beginning to appear with increasing frequency in general as well as specialized medical journals. Hemorheology is also just beginning to creep into the undergraduate medical curriculum. Therefore, the majority of graduate doctors are unequipped to assess the place of hemorheology in the overall framework of circulatory physiology and pathology or to assess its relevance to their everyday practice. It is hoped that this book will fill this gap. The approach of the book is interdisciplinary. The first part deals with basic principles of blood flow, circulation and hemorheology. It has been written with the general doctor in mind, who has no special knowledge of hemodynamics and rheological concepts, terminology or methodology. To maintain the emphasis on practical clinical applications, all the chapters in the second part of the book have been written by clinical specialists practicing in the individual areas of disease. The book is so designed that clinicians may be able to read the relevant chapters in the second part of the book in isolation, using the basic science aspects contained in the first part of the book as reference chapters.

Coronary Microvascular Dysfunction

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Publisher : Springer Science & Business Media
ISBN 13 : 8847053676
Total Pages : 263 pages
Book Rating : 4.70/5 ( download)

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Book Synopsis Coronary Microvascular Dysfunction by : Filippo Crea

Download or read book Coronary Microvascular Dysfunction written by Filippo Crea and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Current Advances in Basic and Clinical Microcirculatory Research

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Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805530422
Total Pages : 398 pages
Book Rating : 4.20/5 ( download)

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Book Synopsis Current Advances in Basic and Clinical Microcirculatory Research by : David H. Lewis

Download or read book Current Advances in Basic and Clinical Microcirculatory Research written by David H. Lewis and published by S. Karger AG (Switzerland). This book was released on 1979 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: