Chemical Biology Of Natural Products

Author : David J. Newman
Publisher : CRC Press
ISBN 13 : 1351643282
Total Pages : 622 pages
Book Rating : 4.83/5 ( download)

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Download or read book Chemical Biology of Natural Products written by David J. Newman and published by CRC Press. This book was released on 2017-09-22 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.

Author : Natanya Civjan
Publisher : John Wiley & Sons
ISBN 13 : 1118101170
Total Pages : 437 pages
Book Rating : 4.79/5 ( download)

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Download or read book Natural Products in Chemical Biology written by Natanya Civjan and published by John Wiley & Sons. This book was released on 2012-07-03 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.

Author :
Publisher : Elsevier
ISBN 13 : 0081026919
Total Pages : 4266 pages
Book Rating : 4.15/5 ( download)

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Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience

Author : Goutam Brahmachari
Publisher : John Wiley & Sons
ISBN 13 : 3527337946
Total Pages : 544 pages
Book Rating : 4.41/5 ( download)

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Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by John Wiley & Sons. This book was released on 2015-03-23 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Author :
Publisher : Elsevier
ISBN 13 : 0080453821
Total Pages : 7944 pages
Book Rating : 4.28/5 ( download)

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Download or read book Comprehensive Natural Products II written by and published by Elsevier. This book was released on 2010-03-05 with total page 7944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content

Author : Nick J Westwood
Publisher : Royal Society of Chemistry
ISBN 13 : 178801507X
Total Pages : 339 pages
Book Rating : 4.73/5 ( download)

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Download or read book Chemical and Biological Synthesis written by Nick J Westwood and published by Royal Society of Chemistry. This book was released on 2018-08-16 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.

Author : Raymond Cooper
Publisher : CRC Press
ISBN 13 : 1466567619
Total Pages : 210 pages
Book Rating : 4.10/5 ( download)

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Download or read book Natural Products Chemistry written by Raymond Cooper and published by CRC Press. This book was released on 2014-07-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature may possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. Natural Products Chemistry: Sources, Separations and Structures presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. This book emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry. A basic introduction, the book describes the whole cycle from farm to final compound, backed up by case studies drawn from industry and research applications. It broadens the scope of applications and draws upon examples from various sources. Natural products chemistry, as taught today, draws its examples mainly from marine chemistry or plant chemistry; however, there is also a fascinating and rich world of fermented (microbial and algal) products leading to complex structures. Thus, the book draws upon examples from the microbial world and from insects too. Therefore, this is a source of bioactive metabolites, not traditionally available in academic settings, more the mainstay of the pharmaceutical industry. Providing a roadmap of the process of collecting a compound from nature, isolating the active ingredient, and determining the chemical structure, this book provides a unique approach to the world of natural products.

Author : Jie Jack Li
Publisher : Springer Science & Business Media
ISBN 13 : 3642340652
Total Pages : 292 pages
Book Rating : 4.59/5 ( download)

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Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Author : Antony D. Buss
Publisher : Royal Society of Chemistry
ISBN 13 : 0854041931
Total Pages : 459 pages
Book Rating : 4.30/5 ( download)

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Download or read book Natural Product Chemistry for Drug Discovery written by Antony D. Buss and published by Royal Society of Chemistry. This book was released on 2010 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive summary of where natural product chemistry is today in drug discovery. It covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products.

Author : Sunil Kumar Talapatra
Publisher : Springer
ISBN 13 : 3642454100
Total Pages : 1197 pages
Book Rating : 4.03/5 ( download)

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Download or read book Chemistry of Plant Natural Products written by Sunil Kumar Talapatra and published by Springer. This book was released on 2015-03-05 with total page 1197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.