Cellular Therapies In Cancer

Author : Daniel W. Lee
Publisher : Elsevier Health Sciences
ISBN 13 : 0323755976
Total Pages : 246 pages
Book Rating : 4.79/5 ( download)

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Download or read book Chimeric Antigen Receptor T-Cell Therapies for Cancer E-Book written by Daniel W. Lee and published by Elsevier Health Sciences. This book was released on 2019-11-30 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.

Author : Armin Ghobadi
Publisher : Springer Nature
ISBN 13 : 303087849X
Total Pages : 371 pages
Book Rating : 4.98/5 ( download)

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Download or read book Gene and Cellular Immunotherapy for Cancer written by Armin Ghobadi and published by Springer Nature. This book was released on 2022-01-01 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These advances have dramatically improved the management of patients with relapsed refractory lymphoma, myeloma and leukemia. Gene and Cellular Immunotherapy for Cancer offers readers a comprehensive review of current cellular and gene-based immunotherapies. Divided into eighteen cohesive chapters, this book provides an in-depth and detailed look into cellular-based immunotherapies including CAR-T, TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers, focusing on their historical perspectives, biology, development and manufacturing, toxicities and more. Edited by two leading experts on gene and cellular immunotherapy, the book will feature chapters written by a diverse collection of recognized and up-and-coming experts and researchers in the field, providing oncologists, immunologists, researchers and clinical and basic science trainees with a bench to bedside view of the latest developments in the field.

Author : Katy Rezvani
Publisher : Frontiers Media SA
ISBN 13 : 2889633780
Total Pages : 182 pages
Book Rating : 4.84/5 ( download)

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Download or read book Cellular Therapies in Cancer written by Katy Rezvani and published by Frontiers Media SA. This book was released on 2020-01-16 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Robert E Hawkins
Publisher : World Scientific
ISBN 13 : 9814618535
Total Pages : 210 pages
Book Rating : 4.33/5 ( download)

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Download or read book Cellular Therapy Of Cancer: Development Of Gene Therapy Based Approaches written by Robert E Hawkins and published by World Scientific. This book was released on 2014-05-05 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods of gene transfer to T cells, review of cell processing methods and clinical trial design. Written by leadings scientists in the field, this up-to-date review on cancer research will be an important reference source to the researchers and healthcare professionals in the field.

Author : "Patrick" Peishun Shou
Publisher : Frontiers Media SA
ISBN 13 : 2832528902
Total Pages : 424 pages
Book Rating : 4.07/5 ( download)

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Download or read book Adoptive cellular therapies in immunoregulation and cancer written by "Patrick" Peishun Shou and published by Frontiers Media SA. This book was released on 2023-07-05 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.81/5 ( download)

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Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Surajit Pathak
Publisher : Springer Nature
ISBN 13 : 9811551200
Total Pages : 369 pages
Book Rating : 4.08/5 ( download)

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Download or read book Cancer Stem Cells: New Horizons in Cancer Therapies written by Surajit Pathak and published by Springer Nature. This book was released on 2020-10-17 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.

Author : R.J. Buka
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318067423
Total Pages : 71 pages
Book Rating : 4.22/5 ( download)

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Download or read book Fast Facts: CAR T-Cell Therapy written by R.J. Buka and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chimeric antigen receptor (CAR) T cells are genetically engineered immune cells that can seek out and destroy cancer cells. The results from their use in cancer immunotherapy have been very promising, but treatment is often associated with frequent, serious short-term toxicities. 'Fast Facts: CAR-T Therapy' explains what CAR T cells are and how they were developed, discusses the results of clinical trials and the management of toxicities, and outlines future improvements and applications. It is ideal reading for any healthcare professional wanting to know more about this exciting therapeutic field. Table of Contents: • CAR T cells • Clinical application • Practical aspects • Future directions

Author : Prashant Trikha
Publisher : Frontiers Media SA
ISBN 13 : 2889635643
Total Pages : 192 pages
Book Rating : 4.41/5 ( download)

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Download or read book Current Perspectives, Challenges and Advances in Cell Based Therapies written by Prashant Trikha and published by Frontiers Media SA. This book was released on 2020-03-24 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Edwin P. Alyea, III, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826139949
Total Pages : 353 pages
Book Rating : 4.48/5 ( download)

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Download or read book Handbook of Stem Cell Transplantation and Cellular Therapy Management written by Edwin P. Alyea, III, MD and published by Springer Publishing Company. This book was released on 2020-09-29 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Stem Cell Transplantation and Cellular Therapy Management provides an evidence-based practical guide for clinicians and practitioners who treat cancer patients with these challenging and innovative techniques. The handbook begins with chapters on autologous transplantation for myeloma and lymphoma and allogenic transplantation for leukemia, lymphoma, and myelodysplastic syndrome. Further chapters cover the standards of care for managing adverse events related to acute graft-versus-host disease, chronic graft-versus-host disease, infections of bacterial, fungal, and viral nature, lymphoproliferative disease, pulmonary complications, renal complications, and more clinical issues. Concluding chapters address new CAR T-cell therapies, including their mechanisms of action, indications, and unique associated toxicities, in addition to a chapter dedicated to biostatistics and clinical trials. Throughout the book, extensive tables, flow diagrams, and other figures highlight, simplify, and illustrate key concepts. Written by experienced clinicians at the world-renowned Dana Farber Cancer Center and Harvard Medical School in Boston as well as leading experts at other institutions, this stem cell transplantation handbook combines the clinical knowledge, expertise and practical application of these potential life-saving cell therapies in one quick, point-of-care reference. With real-world clinical vignettes interwoven among the chapters, this handbook is an essential resource for anyone managing patients being treated with stem cell transplantation or cellular therapies. Key Features: Provides latest insights and recommendations for managing challenging treatment complications and adverse events Consolidates key information such as diagnosis criteria, disease staging, common complications, and more using detailed tables and diagrams Shares real-world clinical vignette examples, which provide insight into clinical assessment, treatment, and management Emphasizes patient management and best practices Discusses short- and long-term risks for stem cell transplantation and cellular therapy