Cell Survival And Cell Death Second Edition

Author : Kim Newton
Publisher :
ISBN 13 : 9781621823575
Total Pages : pages
Book Rating : 4.71/5 ( download)

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Download or read book Cell Survival and Cell Death written by Kim Newton and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cell death plays a critical role in development, normal physiology, and many diseases, including cancer. This new edition on the subject provides a state-of-the-art summary of our understanding of the signaling mechanisms that regulate cell survival and cell death, along with the molecular mechanisms underlying the various different death processes seen in cells"--

Author : Kim Newton
Publisher :
ISBN 13 : 9781621823551
Total Pages : 320 pages
Book Rating : 4.55/5 ( download)

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Download or read book Cell Survival and Cell Death, Second Edition written by Kim Newton and published by . This book was released on 2020-03-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell death plays a critical role in development, normal physiology, and many diseases, including cancer. This new edition on the subject provides a state-of-the-art summary of our understanding of the signaling mechanisms that regulate cell survival and cell death, along with the molecular mechanisms underlying the various different death processes seen in cells. Topics covered in this essential volume include: - Phagocyte Responses to Cell Death in Flies - Targeting Death Receptors in Cancer and Inflammation - Cell Death and Neurodegeneration - Neutrophil Extracellular Traps in Host Defense

Author : Douglas R. Green
Publisher :
ISBN 13 : 9781621822141
Total Pages : 250 pages
Book Rating : 4.41/5 ( download)

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Download or read book Cell Death written by Douglas R. Green and published by . This book was released on 2018-09-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: One million cells in our bodies die every second--they commit suicide by a mechanism known as apoptosis. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system. In Cell Death, Douglas Green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Taking a bottom-up approach, he starts with the enzymes that perform the execution process (a family of proteases termed caspases) and examines their cellular targets and the ways in which they are activated. He then looks at the molecular machinery that links signals that cause cell death to caspases, emphasizing the importance of the BCL-2 family of proteins and the role of cytochrome c released from mitochondria. The final stage of the process, phagocytic removal of dead or dying cells, is also covered. Green outlines the roles of apoptosis and death mechanisms such as necrosis in embryogenesis, neuronal selection, and the development of self-tolerance in the immune system. In addition, he explains how cell death defends the body against cancer and traces the evolutionary origins of the apoptosis machinery back over a billion years. This new edition contains critical new information on recent exciting advances in the field, such as new forms for cell death and important insights into the mechanisms and control of apoptosis. The book is thus of great use to all biologists interested in how cells function in the context of multicellular organisms and will appeal to everyone from undergraduates encountering the topic for the first time to researchers actively working in the field.

Author : Eric H. Baehrecke
Publisher : Much-in-Little
ISBN 13 : 9781936113316
Total Pages : 0 pages
Book Rating : 4.17/5 ( download)

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Download or read book Cell Survival and Cell Death written by Eric H. Baehrecke and published by Much-in-Little. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Billions of cells die every day in the human body. This is required for normal development and physiology, as well as the elimination of errant cells. Apoptosis and other cell death mechanisms are complex and carefully controlled. If cell death does not occur when it should, cancer and other diseases may develop. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of apoptosis, autophagy, and necrosis. Contributors describe in detail the molecular mechanisms of cell death signaling, including death receptor-ligand systems, BCL-2 family proteins, mitochondrial permeabilization, the endocytic pathway, caspases, and signals that trigger the clearance of dying cells. Survival mechanisms and proteins such as IAPs that antagonize cell death are also described. This volume includes discussion of tumor suppression, the altered metabolism of cancer cells, and the development of therapeutic drugs. It is an essential reference for cell and developmental biologists, cancer biologists, and all who want to understand when and how cell death is required for life.

Author : Douglas R. Green
Publisher :
ISBN 13 : 9781621822134
Total Pages : 250 pages
Book Rating : 4.33/5 ( download)

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Download or read book Cell Death written by Douglas R. Green and published by . This book was released on 2018-09-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: One million cells in our bodies die every second--they commit suicide by a mechanism known as apoptosis. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system. In Cell Death, Douglas Green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Taking a bottom-up approach, he starts with the enzymes that perform the execution process (a family of proteases termed caspases) and examines their cellular targets and the ways in which they are activated. He then looks at the molecular machinery that links signals that cause cell death to caspases, emphasizing the importance of the BCL-2 family of proteins and the role of cytochrome c released from mitochondria. The final stage of the process, phagocytic removal of dead or dying cells, is also covered. Green outlines the roles of apoptosis and death mechanisms such as necrosis in embryogenesis, neuronal selection, and the development of self-tolerance in the immune system. In addition, he explains how cell death defends the body against cancer and traces the evolutionary origins of the apoptosis machinery back over a billion years. This new edition contains critical new information on recent exciting advances in the field, such as new forms for cell death and important insights into the mechanisms and control of apoptosis. The book is thus of great use to all biologists interested in how cells function in the context of multicellular organisms and will appeal to everyone from undergraduates encountering the topic for the first time to researchers actively working in the field.

Author : Tobias Ntuli
Publisher : BoD – Books on Demand
ISBN 13 : 9535122363
Total Pages : 448 pages
Book Rating : 4.64/5 ( download)

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Download or read book Cell Death written by Tobias Ntuli and published by BoD – Books on Demand. This book was released on 2015-12-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

Author : Xiao-Ming Yin
Publisher : Humana Press
ISBN 13 : 9781603273800
Total Pages : 707 pages
Book Rating : 4.08/5 ( download)

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Download or read book Essentials of Apoptosis written by Xiao-Ming Yin and published by Humana Press. This book was released on 2009-06-04 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.

Author : Xiao-Ming Yin
Publisher : Humana Press
ISBN 13 : 9781493956494
Total Pages : 770 pages
Book Rating : 4.93/5 ( download)

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Download or read book Essentials of Apoptosis written by Xiao-Ming Yin and published by Humana Press. This book was released on 2016-05-01 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the comprehensive, concise summary of apoptosis research, a topic that has grown fast in recent years. It covers the major concepts, molecular architecture, biochemical pathways, and pathophysiological significance of apoptosis.

Author : James A. Radosevich
Publisher : John Wiley & Sons
ISBN 13 : 1119432421
Total Pages : 784 pages
Book Rating : 4.25/5 ( download)

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Download or read book Apoptosis and Beyond, 2 Volume Set written by James A. Radosevich and published by John Wiley & Sons. This book was released on 2018-12-27 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.

Author : Hao Wu
Publisher : Springer Science & Business Media
ISBN 13 : 1461493021
Total Pages : 280 pages
Book Rating : 4.20/5 ( download)

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Download or read book Cell Death written by Hao Wu and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning from centuries of anecdotal descriptions of cell death, such as those on the development of the midwife toad in 1842 by Carl Vogt, to modern-day investigations of cell death as a biological discipline, it has become accepted that cell death in multicellular organisms is a normal part of life. This book provides a comprehensive view of cell death, from its mechanisms of initiation and execution, to its implication in human disease and therapy. Physiological cell death plays critical roles in almost all aspects of biology, and the book details its roles in lymphocyte homeostasis, neuronal function, metabolism, and the DNA damage response. When physiological cell death goes awry, diseases can arise, and cancer is presented as a central paradigm for the consequences of derangements in the interplay between cell survival and cell death. At the same time, the potential promise of targeted therapies aimed at interdicting cell death machineries are also discussed extensively. The molecular mechanisms that underlie apoptotic cell death are illustrated from the perspectives of both the intrinsic, mitochondrial apoptotic pathway and the extrinsic, death receptor pathway. Key players in these pathways, such as the Bcl2 family proteins, cytochrome c, Apaf-1, caspases, death receptor adapter proteins, and inhibitor of apoptosis proteins, are presented from both functional and structural angles. Until only a few years ago, programmed cell death has been considered essentially synonymous with apoptosis. However, we now know that programmed cell death can also take other forms such as necrosis or necroptosis, and to this end, the mechanisms that underlie programmed necrosis in development and host defense are illustrated. The past twenty plus years have seen an incredible growth of research in cell death, with one breakthrough after another, and the legacy still goes on with constant new surprises and findings. Long live cell death!