Cardiovascular Genomics

Author : Mohan K. Raizada
Publisher : Springer Science & Business Media
ISBN 13 : 1592598838
Total Pages : 367 pages
Book Rating : 4.30/5 ( download)

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Download or read book Cardiovascular Genomics written by Mohan K. Raizada and published by Springer Science & Business Media. This book was released on 2008-02-24 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

Author : Dhavendra Kumar
Publisher : Springer
ISBN 13 : 3319661140
Total Pages : 920 pages
Book Rating : 4.48/5 ( download)

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Download or read book Cardiovascular Genetics and Genomics written by Dhavendra Kumar and published by Springer. This book was released on 2018-01-17 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practice includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.

Author : Dan M. Roden
Publisher : John Wiley & Sons
ISBN 13 : 9781444311778
Total Pages : 288 pages
Book Rating : 4.78/5 ( download)

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Download or read book Cardiovascular Genetics and Genomics written by Dan M. Roden and published by John Wiley & Sons. This book was released on 2009-04-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.

Author : Victor J. Dzau, MD
Publisher : John Wiley & Sons
ISBN 13 : 0470765941
Total Pages : 328 pages
Book Rating : 4.44/5 ( download)

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Download or read book Cardiovascular Genetics and Genomics for the Cardiologist written by Victor J. Dzau, MD and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way cardiovascular medicine is practiced • what material has immediate relevance to the practicing clinician • how to incorporate genetics and genomics in your practice to ensure up-to-date patient care The book opens with introductory chapters, then discusses: • cardiovascular single gene disorders • cardiovascular polygenic disorders • therapies and applications Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.

Author : Sanjiv J. Shah, MD
Publisher : Springer Publishing Company
ISBN 13 : 162070014X
Total Pages : 326 pages
Book Rating : 4.43/5 ( download)

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Download or read book Cardiovascular Genetics and Genomics in Clinical Practice written by Sanjiv J. Shah, MD and published by Springer Publishing Company. This book was released on 2014-11-10 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide a unique approach to cardiovascular genetics and genomics through utilizing clinical cases to illustrate the basic science concepts as the practitioner will encounter them in regular clinical practice. Through the teaching value of real-world case discussions, the principles of cardiovascular genetics and genomics can be illustrated clearly and memorably, and the clinician will be able to relate the cases shown in the book with those seen in direct experience. The book opens with a "primer" of the basic scientific concepts, providing the reader with a clear, easy to understand "toolkit" for the discussions of the genetic science in clinical practice.

Author : José Marín-García
Publisher : Academic Press
ISBN 13 : 0124046428
Total Pages : 935 pages
Book Rating : 4.29/5 ( download)

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Download or read book Post-Genomic Cardiology written by José Marín-García and published by Academic Press. This book was released on 2014-05-09 with total page 935 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Author : Keith DiPetrillo
Publisher : Humana Press
ISBN 13 : 9781607612483
Total Pages : 350 pages
Book Rating : 4.88/5 ( download)

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Download or read book Cardiovascular Genomics written by Keith DiPetrillo and published by Humana Press. This book was released on 2009-10-16 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies. In Cardiovascular Genomics: Methods and Protocols, experts in the field provide methods for cardiovascular phenotyping of rodent models in the first section of the volume and for statistical and bioinformatic integration of phenotype data with genome-wide genotype and expression data in the second section. Understanding these diverse methods will allow an individual laboratory to utilize these genomic methods independently or to better prepare for collaboration with scientists having expertise in other disciplines in order to uncover genes affecting cardiovascular disease. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary equipment, materials, and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Cutting-edge and easy-to-use, Cardiovascular Genomics: Methods and Protocols will enable researchers to identify causal genes and novel molecular targets that can lead to vital new treatments for cardiovascular disease.

Author : Geoffrey S. Ginsburg
Publisher : Academic Press
ISBN 13 : 0128018259
Total Pages : 336 pages
Book Rating : 4.55/5 ( download)

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Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2017-11-17 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Cardiovascular Disease, Third Edition, focuses on the applications of genome discovery on the broad spectrum of cardiovascular disorders. Each chapter is organized for the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Presents a comprehensive volume written and edited by cardiovascular genomic specialists Covers succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine into practice Provides an overview on major opportunities for genomic and personalized medicine in practice Includes case studies that highlight the practical use of genomics in the management of patients

Author : Hong Jiang
Publisher : Springer
ISBN 13 : 9811314292
Total Pages : 374 pages
Book Rating : 4.92/5 ( download)

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Download or read book Heart Genomics written by Hong Jiang and published by Springer. This book was released on 2018-10-11 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.

Author : Dhavendra Kumar
Publisher : Oxford University Press, USA
ISBN 13 : 0195368959
Total Pages : 623 pages
Book Rating : 4.56/5 ( download)

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Download or read book Principles and Practice of Clinical Cardiovascular Genetics written by Dhavendra Kumar and published by Oxford University Press, USA. This book was released on 2010 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consisting of contributions from experts in all specialties of cardiovascular genetics and applied clinical cardiology, Principles and Practice of Clinical Cardiovascular Genetics serves as the comprehensive volume for any clinician or resident in cardiology and genetics. Each chapter provides a detailed and comprehensive account on the molecular genetics and clinical practice related to specific disorders or groups of disorders, including Marfan syndrome, thoracic and abdominal aortic aneurysms, hypertrophic, dilated and restrictive cardiomyopathies and Arrhythmogenic right ventricular cardiomyopathy, as well as many others. All sections comprehensively address cardiovasuclar genetic disorders, beginning with an introduction and including separate sections on the disease's basic biological aspects, specific genetic mechanisms or issues, clinical aspects, genetic management (e.g., genetic diagnosis, risk assessment, genetic counseling, genetic testing), and clinical management issues. The final section exclusively addresses the management of cardiovascular genetic disorders, specifically considering stem cell therapy, genetic counseling, pharmacogenomics and the social and ethical issues surrounding disease treatment.