Carbohydrate Protein Interaction

Author : D. Wade Abbott
Publisher : Humana Press
ISBN 13 : 9781493968985
Total Pages : 311 pages
Book Rating : 4.8X/5 ( download)

DOWNLOAD NOW!

Download or read book Protein-Carbohydrate Interactions written by D. Wade Abbott and published by Humana Press. This book was released on 2017-05-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a wide-ranging tool for studying protein-carbohydrate interactions that extend from traditional biochemical methods to state-of-the-art techniques. This book focuses on four different research themes: Part I describes methods for screening and quantifying CAZyme activity; Part II contains methods for investigating the interactions between proteins and carbohydrate ligands; Part III discusses methods for the visualization of carbohydrates and protein-carbohydrate complexes; and Part IV focuses on structural and “omic” approaches for studying systems of CAZymes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Protein-Carbohydrate Interactions: Methods and Protocols is a valuable resource to the glycomics research community. In this continuously advancing field, the methods in this book highlight the biology of glycomics, thus driving biotechnological innovation and solutions for human health and sustainable resources within the emerging green community.

Author : Adrienne E. Clarke
Publisher : Springer Science & Business Media
ISBN 13 : 3642466419
Total Pages : 158 pages
Book Rating : 4.10/5 ( download)

DOWNLOAD NOW!

Download or read book Carbohydrate-Protein Interaction written by Adrienne E. Clarke and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate as the primary product of photosynthesis has a vital role in the maintenance of life on this planet. Until relatively recently, interest in complex carbohydrates focussed on their structural role in the extracellular matrix/ cell wall of animal, plant, and microbial cells and on their role as energy sources (e.g., starch and glycogen) and struc tural components (e.g., cellulose) in natural products. There was, however, indirect evidence that carbohydrates could play an informational role; this evidence was from the find ing last century that plant lectins caused specific agglutina tion of certain animal cells and, more recently, that the agglutination was mediated by interactions between the plant lectin and cell surface carbohydrates. It is now clear that endogenous carbohydrate binding proteins are important in cell-cell recognition phenomena in animal systems. Recently, impressive evidence has been presented that complex oligosaccharides, derived from cell walls, are also important in plant recognition events, for example in signalling the defence mechanisms of a plant to respond to attack by insects and microbial pathogens.

Author : Bertram O. Fraser-Reid
Publisher : Springer Science & Business Media
ISBN 13 : 3540361545
Total Pages : 2847 pages
Book Rating : 4.41/5 ( download)

DOWNLOAD NOW!

Download or read book Glycoscience written by Bertram O. Fraser-Reid and published by Springer Science & Business Media. This book was released on 2008-04-14 with total page 2847 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.

Author :
Publisher :
ISBN 13 : 9780841204669
Total Pages : 222 pages
Book Rating : 4.67/5 ( download)

DOWNLOAD NOW!

Download or read book Carbohydrate-protein Interaction written by and published by . This book was released on 1979 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Roger Christopher Diehl
Publisher :
ISBN 13 :
Total Pages : 102 pages
Book Rating : 4.37/5 ( download)

DOWNLOAD NOW!

Download or read book CH-[pi] Interactions Play a Central Role in Protein Recognition of Carbohydrates written by Roger Christopher Diehl and published by . This book was released on 2021 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate-protein interactions play a central role in biology, but knowledge of the forces underlying them is limited. Carbohydrates are generally hydrophilic and therefore present unique challenges in their recognition. One underappreciated force involved in carbohydrate-protein interactions is the CH-[pi] interaction, an attractive interaction between the aliphatic protons of a carbohydrate and the [pi] system of an aromatic ring. In this thesis, I examine the fundamental nature, strength, and biological significance of this interaction, largely in the context of a family of carbohydrate-binding proteins known as galectins. In Chapter 1, I review previous knowledge of the forces underlying carbohydrate-binding proteins and the forces they utilize to bind their ligands. In particular, I focus on CH-[pi] interactions and galectins. In Chapter 2, I examine the forces that contribute to CH-[pi] interactions in the context of carbohydrates and aromatic compounds in aqueous solution. I find the CH-[pi] interaction to be electronic in nature, and demonstrate its selectivity between different carbohydrates. In Chapter 3, I determine the contribution of the CH-[pi] interaction to the ligand binding of galectin-3, a human carbohydrate-binding protein of medical significance. The data demonstrate that the CH-[pi] interaction accounts for a majority of the binding energy. In Chapter 4, I explore the biological implications of the CH-[pi] interaction in galectin-3. I demonstrate that the CH-[pi] interaction is critical for the biological activities of galectin-3. In Chapter 5, I propose several directions future researchers could take to extend this work. For three of four directions, I present the progress I have made during my studies. The work contained within this thesis demonstrates that CH-[pi] interactions play a central role in protein-carbohydrate interactions at both a molecular level and a biological level. Understanding the CH-[pi] interaction is key to explaining and predicting the activity of carbohydrate-binding proteins.

Author : Peng George Wang
Publisher :
ISBN 13 : 9780841298989
Total Pages : pages
Book Rating : 4.8X/5 ( download)

DOWNLOAD NOW!

Download or read book Glycan-Based Cellular Communication written by Peng George Wang and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.18/5 ( download)

DOWNLOAD NOW!

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Author : M Michael Gromiha
Publisher : World Scientific
ISBN 13 : 9811211884
Total Pages : 424 pages
Book Rating : 4.81/5 ( download)

DOWNLOAD NOW!

Download or read book Protein Interactions: Computational Methods, Analysis And Applications written by M Michael Gromiha and published by World Scientific. This book was released on 2020-03-05 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is indexed in Chemical Abstracts ServiceThe interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design.This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules.

Author : American Chemical Society. Division of Carbohydrate Chemistry
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.95/5 ( download)

DOWNLOAD NOW!

Download or read book Carbohydrate-protein Interaction written by American Chemical Society. Division of Carbohydrate Chemistry and published by . This book was released on 1979 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Thomas Peters
Publisher : Springer Science & Business Media
ISBN 13 : 3540490779
Total Pages : 317 pages
Book Rating : 4.77/5 ( download)

DOWNLOAD NOW!

Download or read book Bioactive Conformation I written by Thomas Peters and published by Springer Science & Business Media. This book was released on 2007-01-05 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts