Carbohydrate Mimics

Author : Yves Chapleur
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 638 pages
Book Rating : 4.94/5 ( download)

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Download or read book Carbohydrate Mimics written by Yves Chapleur and published by Wiley-VCH. This book was released on 1998-09-10 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Mimics Concepts and Methods Edited by Yves Chapleur Apart from the various functions of carbohydrates in natural processes they are important building blocks for drugs, especially antibiotics. In addition, carbohydrates are considered as important structures in the immunological recognition process of the antigen-antibody reaction. The modification of the structure and thereby the chemistry of substrates is a common procedure in nature. This naturally occurring process is reflected in the concept of molecular mimicry, which has become a useful approach in drug discovery. The search for carbohydrate analogues that exhibit better binding activity, biological activity, and stability began with the synthesis of azasugars. A lot of structural modifications around the anomeric center of carbohydrates has been achieved over the last decade, and these are summarized in terms of the different chemical and biological aspects of carbohydrate mimics in one part of this book. In addition to the well established fields of C-glycosides, azasugars and carbasugars the other part of the book focusses on outstanding achievements in carbohydrate mimic research. Everybody who is active in carbohydrate research or is interested in moving into this exciting field will benefit from this up-to-date source of informations. The leading experts in this field describe their scientific approaches to real interdisciplinary puzzles. This book should be an inspiration to scientists in organic, medicinal chemistry, biochemistry, and biology.

Author : Robert V. Stick
Publisher : Academic Press
ISBN 13 : 9780126709605
Total Pages : 280 pages
Book Rating : 4.02/5 ( download)

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Download or read book Carbohydrates written by Robert V. Stick and published by Academic Press. This book was released on 2001-03-13 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the field of carbohydrates from theoretical, mechanistic and practical points of view, topics covered include: synthesis and protecting groups; reactions of monosaccharides; synthesis of the glycosidic linkage; synthesis of oligosaccharides; polysaccharides; and glycoconjugates.

Author : Travis D. Weaver
Publisher :
ISBN 13 :
Total Pages : 262 pages
Book Rating : 4.07/5 ( download)

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Download or read book Synthesis of C-glycosides as Carbohydrate Mimics written by Travis D. Weaver and published by . This book was released on 2005 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Peter H. Seeberger
Publisher : Springer
ISBN 13 : 3319086758
Total Pages : 242 pages
Book Rating : 4.50/5 ( download)

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Download or read book Carbohydrates as Drugs written by Peter H. Seeberger and published by Springer. This book was released on 2014-11-14 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Author : Institute of Medicine (U.S.). Committee on Military Nutrition Research
Publisher : National Academies
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.88/5 ( download)

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Download or read book Fluid Replacement and Heat Stress written by Institute of Medicine (U.S.). Committee on Military Nutrition Research and published by National Academies. This book was released on 1994 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Brian Alvin Johns
Publisher :
ISBN 13 :
Total Pages : 756 pages
Book Rating : 4.23/5 ( download)

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Download or read book Glycomimetics written by Brian Alvin Johns and published by . This book was released on 1997 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Chi-Huey Wong
Publisher : John Wiley & Sons
ISBN 13 : 3527605789
Total Pages : 980 pages
Book Rating : 4.81/5 ( download)

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Download or read book Carbohydrate-based Drug Discovery written by Chi-Huey Wong and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > Chemical Synthesis of Carbohydrates > Carbohydrate Biosynthesis and Metabolism > Carbohydrate Analysis > Cellular Functions of Carbohydrates > Development of Carbohydrate-based Drugs A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.

Author : Amelia Pilar Rauter
Publisher : Royal Society of Chemistry
ISBN 13 : 1849731543
Total Pages : 411 pages
Book Rating : 4.46/5 ( download)

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Download or read book Carbohydrate Chemistry written by Amelia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2011 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Author : Glenn Alan Gaesser
Publisher : Trafford Publishing
ISBN 13 : 1412031648
Total Pages : 242 pages
Book Rating : 4.46/5 ( download)

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Download or read book It's the Calories, Not the Carbs written by Glenn Alan Gaesser and published by Trafford Publishing. This book was released on 2004 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: For today's Americans, it is an obsession. What should I eat? What should I avoid? Which foods should I combine? How do I get "in the zone" or "eat for my type?" We must now choose between "healthy" fats and "unhealthy" fats; "good" carbs and "bad" carbs; and "high glycemic" and "low glycemic." While the formulas for healthful eating increase, so do our waistlines. The perfect example is the low-carbohydrate diet. Since the mid-1990s low-carb diets have made a phenomenal resurgence, led by Dr. Robert Atkins' program, which has been on The New York Times bestseller list continuously for the past five years. But his plan is by no means the only one. Others also are jockeying to take the low-carb crown, including the South Beach Diet, the latest in the low-carb offerings that has pushed its way up the bestseller lists. With this resurgence, many Americans are now avoiding carbs. For the time being, carbs appear to be the "enemy" in many people's minds and stomachs. We emphasize "for the time being" because when it comes to diets, nothing lasts forever. Americans went through a similar obsession with carbohydrate avoidance a few decades ago, when many low-carb diet books topped the bestseller lists in the 1960s and 1970s-including the original version of Atkins' low-carb diet. Despite their popularity, low-carb diets had virtually no measurable effect on our waistlines-the weight of the average U.S. adult at the end of '70s was essentially the same as it was at the start of the previous decade. It seems that a diet limited to primarily protein and fat was not the answer after all. And when it comes to dieting, it seems Americans cannot resist a fad. But no matter what the latest fad diet claims, the bottom line is calories-regardless of type-do count. Unfortunately, Americans seem to have found out the hard way. It's the Calories, Not the Carbs was written in part to clarify this point and set the record straight. It also was written to show you that eating well-and living well-is about giving yourself the best possible intake of nutrients to allow your body to be as healthy as possible and to work as well as it can. It is getting the nutrients your body needs for optimal mental performance and emotional balance. It is not a set of rules. Your body's needs and health goals are completely unique and depend on a whole host of factors-from the strengths and weaknesses you were born with, to the effects your current environment has on you. No single way of eating is perfect for everyone, although there are general guidelines that apply to us all. Whether your personal health goal is to lose weight, maintain your current weight, become more active, have more energy, or just improve your overall health and fitness-this guide will show you how to use the Food Guide Pyramid, listen to your body, and become more active to make lasting, healthful lifestyle changes for health and wellness ...and to say goodbye to fad diets of all types for good.

Author : Binghe Wang
Publisher : John Wiley & Sons
ISBN 13 : 1118017579
Total Pages : 448 pages
Book Rating : 4.79/5 ( download)

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Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.