Cancer Risk Assessment

Author : Graham A. Colditz
Publisher : Jones & Bartlett Learning
ISBN 13 : 9780763718831
Total Pages : 372 pages
Book Rating : 4.31/5 ( download)

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Download or read book Handbook of Cancer Risk Assessment and Prevention written by Graham A. Colditz and published by Jones & Bartlett Learning. This book was released on 2004 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for health care providers at all levels, this handbook covers in depth fourteen of the most common cancers in the U.S. -- providing for each a scientific summary of risk factors, a risk assessment tool for patients, and helpful hints to promote risk-reducing lifestyle changes. Additional chapters focus specifically on five key lifestyle behaviors that lower not only the risk of cancer but also the risk of other chronic diseases.Throughout its entirety, the handbook emphasizes the importance of communicating risk effectively to patients. A chapter is devoted solely to this topic, and risk information about each cancer is presented in a variety of formats. Finally, the risk assessment tools -- adaptations from the popular website Your Cancer Risk -- offer patients the option to estimate their cancer risk and receive practical, personal tips for lowering that risk.At a time when the public is surrounded by conflicting health messages, especially from the media and the Internet, the Handbook of Cancer Risk-Assessment and Prevention is an essential source for reliable, up-to-date information on cancer prevention. It delivers positive health messages and offers practical advice that health care providers can use to help patients implement strategies to prevent cancer and other chronic diseases.

Author : Wai Nang Choy
Publisher : CRC Press
ISBN 13 : 0824745221
Total Pages : 405 pages
Book Rating : 4.26/5 ( download)

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Download or read book Genetic Toxicology and Cancer Risk Assessment written by Wai Nang Choy and published by CRC Press. This book was released on 2001-08-31 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents state-of-the-art regulatory cancer risk assessment models including a biologically based model for two-hit carcinogenesis and cell proliferation! This book comprehensively reviews the various roles of genetic toxicology in human cancer risk assessment conducted by United States and worldwide regulatory agencies-discussing hazard identification, dose-response relationships, exposure assessment, and current practices of risk characterization. Examines predictive values of mutagenicity tests, mechanisms of carcinogenesis, and conventional genotoxicity tests required by the International Conference on Harmonization and the Organization for Economic Cooperation and Development/Environmental Protection Agency guidelines! Comprised of contributions from prominent experts and risk assessors and including nearly 1200 references to facilitate further study, Genetic Toxicology and Cancer Risk Assessment reviews contemporary human cancer genetics as related to the mutagenic nature of carcinogenesis calculates acceptable exposure levels based on a carcinogenic threshold dose for nongenotoxic carcinogens reveals the rationale and methodology of quantitative estimation of human cancer risks using mathematical models discusses the threshold concept of carcinogenesis demonstrates how bacterial mutagenicity assays are the most reliable for predicting rodent carcinogens considers structural activity relationship (SAR) analysis of chemical carcinogenicity describes the emergence of the mouse lymphoma microwell and in vitro micronucleus assays illustrates the use of genetic biomarkers for dosimetry analysis and more! Linking human cancer genetics, mutagenicity assays, mechanisms of carcinogenesis, carcinogenic thresholds, molecular epidemiology, mathematical modeling, and quantitative cancer risk analysis, Genetic Toxicology and Cancer Risk Assessment is a must-have reference for toxicologists; oncologists; geneticists; biostatisticians; reproductive, developmental, cell, and molecular biologists; endocrinologists; biochemists; and upper-level undergraduate, graduate, and medical school students in these disciplines.

Author : Peter G. Shields
Publisher : CRC Press
ISBN 13 : 1000611345
Total Pages : 800 pages
Book Rating : 4.42/5 ( download)

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Download or read book Cancer Risk Assessment written by Peter G. Shields and published by CRC Press. This book was released on 2005-05-24 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: The assessment of cancer risk is a complex process that requires the examination of etiological agents, real-world environments, and individual rates of exposure. This reference offers practical approaches to determine cancer risk in individuals, groups of exposed persons, and the general public in relation to individual genetic and acquired suscep

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.63/5 ( download)

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Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Author : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher : National Academies Press
ISBN 13 : 0309133343
Total Pages : 422 pages
Book Rating : 4.40/5 ( download)

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Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Author : Samuel C. Morris
Publisher : CRC Press
ISBN 13 : 1000147517
Total Pages : 414 pages
Book Rating : 4.13/5 ( download)

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Download or read book Cancer Risk Assessment written by Samuel C. Morris and published by CRC Press. This book was released on 2020-07-24 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the National Academy of Sciences approach to quantitative risk assessment. Emphasizes how an accurate assessment of cancer risk must draw on a wide range of disciplines, such as biology, chemistry, physics, engineering, and the social sciences. Provides tables of Poisson confidence limit fa

Author : Wendell Armstrong
Publisher : Nova Science Publishers
ISBN 13 : 9781634851848
Total Pages : 0 pages
Book Rating : 4.46/5 ( download)

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Download or read book Breast Cancer written by Wendell Armstrong and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer risk prediction models provide an important approach to assess risk and susceptibility by identifying individuals at high risk, facilitating the design and planning of clinical chemoprevention trials, and allowing the evaluation of interventions. Conventional breast cancer risk model includes the cumulative estrogen exposure data such as age, age at menarche and menopause, age at first live birth, and use of HRT in risk calculation, since estrogens are the main risk factor for mammary carcinogenesis. The most widely known and commonly used model for breast cancer risk assessment is the Gail model, which focuses primarily on non-genetic risk factors, with limited information on family history. The first chapter of this book examines breast cancer risk assessment models. The following chapters discuss the association between obesity and breast cancer development; current and future standards for treatment of breast cancer and long term care of patients; and mastectomies and voluntarism.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030904894X
Total Pages : 668 pages
Book Rating : 4.41/5 ( download)

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Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

Author : Ching-Hung Hsu
Publisher : John Wiley & Sons
ISBN 13 : 1118035127
Total Pages : 727 pages
Book Rating : 4.22/5 ( download)

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Download or read book Cancer Risk Assessment written by Ching-Hung Hsu and published by John Wiley & Sons. This book was released on 2010-12-08 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous.

Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.12/5 ( download)

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Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.