Brain Hypoxia And Ischemia New Insights Into Neurodegeneration And Neuroprotection

Author : Natalia N Nalivaeva
Publisher : Frontiers Media SA
ISBN 13 : 2889631176
Total Pages : 162 pages
Book Rating : 4.79/5 ( download)

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Download or read book Brain Hypoxia and Ischemia: New Insights Into Neurodegeneration and Neuroprotection written by Natalia N Nalivaeva and published by Frontiers Media SA. This book was released on 2019-11-15 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Matilde Otero-Losada
Publisher : Frontiers Media SA
ISBN 13 : 2889459543
Total Pages : 114 pages
Book Rating : 4.44/5 ( download)

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Download or read book Neuroprotection in Brain Hypoxia written by Matilde Otero-Losada and published by Frontiers Media SA. This book was released on 2019-08-30 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite compelling preclinical evidence from laboratory models of brain hypoxia suggesting potential neuroprotective strategies, only scattered data are available from clinical studies. A few candidate neuroprotectants have been studied regarding antioxidant, antiapoptotic, anti-excitotoxic, immunomodulatory, and neurotrophic effects. In parallel with clinical innovations, preclinical research initiatives are also identifying new animal models more closely resembling the clinical course and pathology of neurodegenerative diseases. Clarifying the specific mission of the brain cells involved in the damage/repair system in the examined animal models is important to define new therapeutic targets. Following hypoxic damage, detrimental events intermingle with the repairing events in both time- and cellular-dependent fashion. Identifying reliable post-hypoxia brain markers is mandatory to develop potential therapeutic interventions, improving translational research from the experimental observations to the clinical application. A deeper understanding of the precise participation of neurons, glia, and endothelial cells is expected to offer more clues for designing new therapeutic strategies to reduce the current gap among the experimental and the clinical data. One of the main issues should be to study the epigenetic mechanism of neuroprotective agents and their action on the genetic modification induced by hypoxia. Achieving this goal is presumed critical to obtain more conclusive results in patients that by now do not receive appropriate therapy for mitigating the several diseases generated by brain hypoxia. Although a few ongoing studies are evaluating interesting approaches, future research is necessary to come to a novel mechanism of neuroprotection. This book encompasses different chapters conveying the goals and aims of the pertaining research.

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481663615
Total Pages : 196 pages
Book Rating : 4.18/5 ( download)

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Download or read book Brain Ischemia: New Insights for the Healthcare Professional: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Ischemia: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Brain Ischemia: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Brain Ischemia: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Gabriel G. Haddad
Publisher : Springer Science & Business Media
ISBN 13 : 1603275797
Total Pages : 363 pages
Book Rating : 4.98/5 ( download)

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Download or read book Brain Hypoxia and Ischemia written by Gabriel G. Haddad and published by Springer Science & Business Media. This book was released on 2009-01-06 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development. This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

Author : Koji Shimoji
Publisher : Springer Science & Business Media
ISBN 13 : 4431684670
Total Pages : 166 pages
Book Rating : 4.71/5 ( download)

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Download or read book Molecular Biology and Brain Ischemia written by Koji Shimoji and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest advances in molecular neurobiology have contributed significantly to understanding the pathophysiology of brain ischemia/hypoxia and have led to more effective measures to protect against ischemic brain damage. An especially important feature of this book is the new insight it provides into the molecular neurobiology of neurotransmission, the functional structures of glutaminergic receptors, the functional proteins of synapses, and synaptic plasticity. Recent progress is reported in elucidating the pathophysiological roles of NO, free radicals, and intracellular pH and calcium ions in brain ischemia/hypoxia, and a unique approach for protective and therapeutic measures against this condition is described. Molecular Neurobiology and Brain Ischemia will be of special interest to researchers and practitioners in neurobiology and related fields, including neurosurgeons.

Author : Eetu Hämäläinen
Publisher : Nova Publishers
ISBN 13 : 9781604561401
Total Pages : 332 pages
Book Rating : 4.08/5 ( download)

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Download or read book New Trends in Brain Hypoxia Ischemia Research written by Eetu Hämäläinen and published by Nova Publishers. This book was released on 2008 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent and significant research from around the world dedicated to brain hypoxia-ischemia which is a disorder characterised by a reduction in oxygen supply (hypoxia) combined with reduced blood flow (ischemia) to the brain. This condition may result from a localised obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain edema; coma; and other conditions.

Author : Hugo Lagercrantz
Publisher : Cambridge University Press
ISBN 13 : 113948558X
Total Pages : 427 pages
Book Rating : 4.86/5 ( download)

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Download or read book The Newborn Brain written by Hugo Lagercrantz and published by Cambridge University Press. This book was released on 2010-01-07 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.

Author : Pardeep Kumar
Publisher : Academic Press
ISBN 13 : 0128217812
Total Pages : 458 pages
Book Rating : 4.18/5 ( download)

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Download or read book Machine Learning, Big Data, and IoT for Medical Informatics written by Pardeep Kumar and published by Academic Press. This book was released on 2021-06-13 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Learning, Big Data, and IoT for Medical Informatics focuses on the latest techniques adopted in the field of medical informatics. In medical informatics, machine learning, big data, and IOT-based techniques play a significant role in disease diagnosis and its prediction. In the medical field, the structure of data is equally important for accurate predictive analytics due to heterogeneity of data such as ECG data, X-ray data, and image data. Thus, this book focuses on the usability of machine learning, big data, and IOT-based techniques in handling structured and unstructured data. It also emphasizes on the privacy preservation techniques of medical data. This volume can be used as a reference book for scientists, researchers, practitioners, and academicians working in the field of intelligent medical informatics. In addition, it can also be used as a reference book for both undergraduate and graduate courses such as medical informatics, machine learning, big data, and IoT. Explains the uses of CNN, Deep Learning and extreme machine learning concepts for the design and development of predictive diagnostic systems. Includes several privacy preservation techniques for medical data. Presents the integration of Internet of Things with predictive diagnostic systems for disease diagnosis. Offers case studies and applications relating to machine learning, big data, and health care analysis.

Author : American College of Obstetricians and Gy
Publisher : American College of Obstetricians and Gynecologists Women's Health Care Physicians
ISBN 13 : 9781934984307
Total Pages : 0 pages
Book Rating : 4.02/5 ( download)

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Download or read book Neonatal Encephalopathy and Neurologic Outcome written by American College of Obstetricians and Gy and published by American College of Obstetricians and Gynecologists Women's Health Care Physicians. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.

Author : Sikha Saha
Publisher : Frontiers Media SA
ISBN 13 : 2889634426
Total Pages : 317 pages
Book Rating : 4.22/5 ( download)

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Download or read book Cerebrovascular and Neurodegenerative Diseases – New Insights into Molecular Cell Biology and Therapeutic Targets written by Sikha Saha and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: