Bone Research Protocols

Author : Miep H. Helfrich
Publisher : Springer Science & Business Media
ISBN 13 : 1592593666
Total Pages : 444 pages
Book Rating : 4.68/5 ( download)

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Download or read book Bone Research Protocols written by Miep H. Helfrich and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade has seen a tremendous advance in our understanding of bone biology. The genes responsible for the majority of rare inherited bone disorders have been identified and much progress has been made in the identification of genes in polygenic disorders such as Paget’s disease and complex multigene diseases such as osteoporosis. Transgenic technology has identified further genes, sometimes unexpectedly, with profound effects on bone. This wealth of new genetic information will undoubtedly lead to extensive cell biological studies to understand the mechanisms by which these gene products affect bone mass and bone strength. In Bone Research Protocols a catalogue of protocols has been assembled to perform such mechanistic studies. In the tradition of the Methods in Molecular Medicine series, the chapters are practical laboratory protocols that should enable the reader to carry out the techniques from scratch. To our knowledge this is the first time such a truly practical manual on well-established bone methods has been assembled, and this volume aims to be complementary to and follow on from the more theoretical Methods in Bone Biology, edited by Arnett and Henderson (1).

Author : Miep H. Helfrich
Publisher : Humana
ISBN 13 : 9781617373213
Total Pages : 0 pages
Book Rating : 4.14/5 ( download)

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Download or read book Bone Research Protocols written by Miep H. Helfrich and published by Humana. This book was released on 2010-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade has seen a tremendous advance in our understanding of bone biology. The genes responsible for the majority of rare inherited bone disorders have been identified and much progress has been made in the identification of genes in polygenic disorders such as Paget’s disease and complex multigene diseases such as osteoporosis. Transgenic technology has identified further genes, sometimes unexpectedly, with profound effects on bone. This wealth of new genetic information will undoubtedly lead to extensive cell biological studies to understand the mechanisms by which these gene products affect bone mass and bone strength. In Bone Research Protocols a catalogue of protocols has been assembled to perform such mechanistic studies. In the tradition of the Methods in Molecular Medicine series, the chapters are practical laboratory protocols that should enable the reader to carry out the techniques from scratch. To our knowledge this is the first time such a truly practical manual on well-established bone methods has been assembled, and this volume aims to be complementary to and follow on from the more theoretical Methods in Bone Biology, edited by Arnett and Henderson (1).

Author : Aymen I. Idris
Publisher :
ISBN 13 : 9781493989973
Total Pages : 670 pages
Book Rating : 4.79/5 ( download)

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Download or read book Bone Research Protocols written by Aymen I. Idris and published by . This book was released on 2019 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Jennifer J. Westendorf
Publisher : Humana Press
ISBN 13 : 9781627038478
Total Pages : 0 pages
Book Rating : 4.77/5 ( download)

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Download or read book Osteoporosis written by Jennifer J. Westendorf and published by Humana Press. This book was released on 2014-11-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of bone cells and tissues at the cellular and molecular levels in a variety of models has revolutionized the field. In this book, leading scientists from around the world share their step-by-step laboratory protocols for studying bone biology. This is the perfect guide for both new and experienced experimentalists attempting to study osteoporosis.

Author : Jennifer J. Westendorf
Publisher : Humana Press
ISBN 13 : 9781588298287
Total Pages : 354 pages
Book Rating : 4.80/5 ( download)

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Download or read book Osteoporosis written by Jennifer J. Westendorf and published by Humana Press. This book was released on 2008-04-16 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of bone cells and tissues at the cellular and molecular levels in a variety of models has revolutionized the field. In this book, leading scientists from around the world share their step-by-step laboratory protocols for studying bone biology. This is the perfect guide for both new and experienced experimentalists attempting to study osteoporosis.

Author : Derek Pearson
Publisher : Springer Science & Business Media
ISBN 13 : 1447137108
Total Pages : 280 pages
Book Rating : 4.08/5 ( download)

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Download or read book Clinical Trials in Osteoporosis written by Derek Pearson and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Trials in Osteoporosis is a practical handbook on clinical trials in the growing field of osteoporosis. Topics covered include study design, technical issues, data collection, quality assurance, data analysis and presentation. It aims to take the user through the process step-by-step from start to finish, also providing a background on regulatory guidelines, ethical implications, endpoints, current therapies and the ideal drug to use. There are no other books at present that specifically address the issue of clinical trials in osteoporosis. A number of issues dealt with in this book have been brought together in one publication for the first time. Clinical Trials in Osteoporosis is intended to serve as a practical manual for clinicians and scientists coming to the subject new and to provide a standard for existing centers to measure themselves against.

Author : Andre J. van Wijnen
Publisher :
ISBN 13 : 9781071609910
Total Pages : pages
Book Rating : 4.12/5 ( download)

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Download or read book Osteoporosis and Osteoarthritis written by Andre J. van Wijnen and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Jennifer J. Westendorf
Publisher :
ISBN 13 : 9781493916191
Total Pages : 214 pages
Book Rating : 4.9X/5 ( download)

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Download or read book Osteoporosis and Osteoarthritis written by Jennifer J. Westendorf and published by . This book was released on 2014 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Osteoporosis and Osteoarthritis expert investigators detail modern tools to enhance discovery in bone and cartilage biology and promote translational research in osteoporosis and osteoarthritis. New chapters describe methods to generate induced pluripotent stem cells, perform high-throughput chromatin analysis, assess loads on bone cells in vivo and in vitro, use state-of-the art imaging techniques to measure articular cartilage thickness and biochemical properties, and establish animal models of osteoarthritis and bone healing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Osteoporosis and Osteoarthritis shares successful techniques that can be applied to the study of either disease.

Author : Darwin J. Prockop
Publisher : Humana Press
ISBN 13 : 9781588297716
Total Pages : 0 pages
Book Rating : 4.13/5 ( download)

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Download or read book Mesenchymal Stem Cells written by Darwin J. Prockop and published by Humana Press. This book was released on 2008-03-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In this essential book, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Cutting edge and easy to use, this book is the perfect resource for scientists attempting to pursue this important and ever-developing field of research.

Author : Hua Gu
Publisher : Springer Science & Business Media
ISBN 13 : 1592597963
Total Pages : 294 pages
Book Rating : 4.63/5 ( download)

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Download or read book B Cell Protocols written by Hua Gu and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: B-lymphocyte development and function remains an exciting area of research for those interested in the physiology and pathology of the immune system in higher animals. While recent advances in genetics and cellular and molecular biology have provided a large spectrum of powerful new experimental tools in this field, it is both time consuming and often very difficult for a student or just any bench-side worker to identify a reliable experimental protocol in the ocean of the literature. The aim of B Cell Protocols is to provide a collection of diverse protocols ranging from the latest inventions and applications to some classic, but still frequently used methods in B-cell biology. The authors of the various chapters are all highly qualified scientists who are either the inventors or expert users of these methods. Their extensive experience in mastering a particular method provides not only the step-by-step details of a reproducible protocol, but also useful troubleshooting tips that readers will appreciate in their daily work. We hope that this book will be helpful for both beginning and experienced researchers in the field in designing or modifying an experimental approach, and exploring a biological question from multiple angles.