Biophysics Of Computation

Author : Christof Koch
Publisher : Oxford University Press
ISBN 13 : 0195181999
Total Pages : 587 pages
Book Rating : 4.99/5 ( download)

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Download or read book Biophysics of Computation written by Christof Koch and published by Oxford University Press. This book was released on 2004-10-28 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.

Author : Ehud Lamm
Publisher : CRC Press
ISBN 13 : 1420087967
Total Pages : 332 pages
Book Rating : 4.63/5 ( download)

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Download or read book Biological Computation written by Ehud Lamm and published by CRC Press. This book was released on 2011-05-25 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of biologically inspired computing, or biological computation, involves the development of new, biologically based techniques for solving difficult computational problems. A unified overview of computer science ideas inspired by biology, Biological Computation presents the most fundamental and significant concepts in this area. In the book

Author : Oren M. Becker
Publisher : CRC Press
ISBN 13 : 9780203903827
Total Pages : 534 pages
Book Rating : 4.2X/5 ( download)

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Download or read book Computational Biochemistry and Biophysics written by Oren M. Becker and published by CRC Press. This book was released on 2001-02-09 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret b

Author : Joel Franklin
Publisher : Cambridge University Press
ISBN 13 : 1107067855
Total Pages : 419 pages
Book Rating : 4.51/5 ( download)

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Download or read book Computational Methods for Physics written by Joel Franklin and published by Cambridge University Press. This book was released on 2013-05-23 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an increasing need for undergraduate students in physics to have a core set of computational tools. Most problems in physics benefit from numerical methods, and many of them resist analytical solution altogether. This textbook presents numerical techniques for solving familiar physical problems where a complete solution is inaccessible using traditional mathematical methods. The numerical techniques for solving the problems are clearly laid out, with a focus on the logic and applicability of the method. The same problems are revisited multiple times using different numerical techniques, so readers can easily compare the methods. The book features over 250 end-of-chapter exercises. A website hosted by the author features a complete set of programs used to generate the examples and figures, which can be used as a starting point for further investigation. A link to this can be found at www.cambridge.org/9781107034303.

Author : Christof Koch
Publisher : MIT Press
ISBN 13 : 0262042819
Total Pages : 277 pages
Book Rating : 4.19/5 ( download)

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Download or read book The Feeling of Life Itself written by Christof Koch and published by MIT Press. This book was released on 2019-09-24 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking argument that consciousness—more widespread than previously assumed—is the feeling of being alive, not a type of computation or a clever hack In The Feeling of Life Itself, Christof Koch offers a straightforward definition of consciousness as any subjective experience, from the most mundane to the most exalted—the feeling of being alive. Psychologists study which cognitive operations underpin a given conscious perception. Neuroscientists track the neural correlates of consciousness in the brain, the organ of the mind. But why the brain and not, say, the liver? How can the brain—three pounds of highly excitable matter, a piece of furniture in the universe, subject to the same laws of physics as any other piece—give rise to subjective experience? Koch argues that what is needed to answer these questions is a quantitative theory that starts with experience and proceeds to the brain. In The Feeling of Life Itself, Koch outlines such a theory, based on integrated information. Koch describes how the theory explains many facts about the neurology of consciousness and how it has been used to build a clinically useful consciousness meter. The theory predicts that many, and perhaps all, animals experience the sights and sounds of life; consciousness is much more widespread than conventionally assumed. Contrary to received wisdom, however, Koch argues that programmable computers will not have consciousness. Even a perfect software model of the brain is not conscious. Its simulation is fake consciousness. Consciousness is not a special type of computation—it is not a clever hack. Consciousness is about being.

Author : Hanspeter A Mallot
Publisher : Springer Science & Business Media
ISBN 13 : 3319008617
Total Pages : 135 pages
Book Rating : 4.15/5 ( download)

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Download or read book Computational Neuroscience written by Hanspeter A Mallot and published by Springer Science & Business Media. This book was released on 2013-05-23 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Neuroscience - A First Course provides an essential introduction to computational neuroscience and equips readers with a fundamental understanding of modeling the nervous system at the membrane, cellular, and network level. The book, which grew out of a lecture series held regularly for more than ten years to graduate students in neuroscience with backgrounds in biology, psychology and medicine, takes its readers on a journey through three fundamental domains of computational neuroscience: membrane biophysics, systems theory and artificial neural networks. The required mathematical concepts are kept as intuitive and simple as possible throughout the book, making it fully accessible to readers who are less familiar with mathematics. Overall, Computational Neuroscience - A First Course represents an essential reference guide for all neuroscientists who use computational methods in their daily work, as well as for any theoretical scientist approaching the field of computational neuroscience.

Author : Christopher P. Fall
Publisher : Springer Science & Business Media
ISBN 13 : 0387224599
Total Pages : 468 pages
Book Rating : 4.96/5 ( download)

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Download or read book Computational Cell Biology written by Christopher P. Fall and published by Springer Science & Business Media. This book was released on 2007-06-04 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.

Author : Shawn T. O'Neil
Publisher :
ISBN 13 : 9780870719264
Total Pages : 0 pages
Book Rating : 4.62/5 ( download)

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Download or read book A Primer for Computational Biology written by Shawn T. O'Neil and published by . This book was released on 2017-12-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Primer for Computational Biology aims to provide life scientists and students the skills necessary for research in a data-rich world. The text covers accessing and using remote servers via the command-line, writing programs and pipelines for data analysis, and provides useful vocabulary for interdisciplinary work. The book is broken into three parts: Introduction to Unix/Linux: The command-line is the "natural environment" of scientific computing, and this part covers a wide range of topics, including logging in, working with files and directories, installing programs and writing scripts, and the powerful "pipe" operator for file and data manipulation. Programming in Python: Python is both a premier language for learning and a common choice in scientific software development. This part covers the basic concepts in programming (data types, if-statements and loops, functions) via examples of DNA-sequence analysis. This part also covers more complex subjects in software development such as objects and classes, modules, and APIs. Programming in R: The R language specializes in statistical data analysis, and is also quite useful for visualizing large datasets. This third part covers the basics of R as a programming language (data types, if-statements, functions, loops and when to use them) as well as techniques for large-scale, multi-test analyses. Other topics include S3 classes and data visualization with ggplot2.

Author : Anthony Scopatz
Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1491901586
Total Pages : 552 pages
Book Rating : 4.88/5 ( download)

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Download or read book Effective Computation in Physics written by Anthony Scopatz and published by "O'Reilly Media, Inc.". This book was released on 2015-06-25 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: More physicists today are taking on the role of software developer as part of their research, but software development isn’t always easy or obvious, even for physicists. This practical book teaches essential software development skills to help you automate and accomplish nearly any aspect of research in a physics-based field. Written by two PhDs in nuclear engineering, this book includes practical examples drawn from a working knowledge of physics concepts. You’ll learn how to use the Python programming language to perform everything from collecting and analyzing data to building software and publishing your results. In four parts, this book includes: Getting Started: Jump into Python, the command line, data containers, functions, flow control and logic, and classes and objects Getting It Done: Learn about regular expressions, analysis and visualization, NumPy, storing data in files and HDF5, important data structures in physics, computing in parallel, and deploying software Getting It Right: Build pipelines and software, learn to use local and remote version control, and debug and test your code Getting It Out There: Document your code, process and publish your findings, and collaborate efficiently; dive into software licenses, ownership, and copyright procedures

Author : Eric L. Schwartz
Publisher : MIT Press
ISBN 13 : 9780262691642
Total Pages : 468 pages
Book Rating : 4.47/5 ( download)

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Download or read book Computational Neuroscience written by Eric L. Schwartz and published by MIT Press. This book was released on 1993-08-26 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thirty original contributions in this book provide a working definition of"computational neuroscience" as the area in which problems lie simultaneously within computerscience and neuroscience. They review this emerging field in historical and philosophical overviewsand in stimulating summaries of recent results. Leading researchers address the structure of thebrain and the computational problems associated with describing and understanding this structure atthe synaptic, neural, map, and system levels.The overview chapters discuss the early days of thefield, provide a philosophical analysis of the problems associated with confusion between brainmetaphor and brain theory, and take up the scope and structure of computationalneuroscience.Synaptic-level structure is addressed in chapters that relate the properties ofdendritic branches, spines, and synapses to the biophysics of computation and provide a connectionbetween real neuron architectures and neural network simulations.The network-level chapters take upthe preattentive perception of 3-D forms, oscillation in neural networks, the neurobiologicalsignificance of new learning models, and the analysis of neural assemblies and local learningrides.Map-level structure is explored in chapters on the bat echolocation system, cat orientationmaps, primate stereo vision cortical cognitive maps, dynamic remapping in primate visual cortex, andcomputer-aided reconstruction of topographic and columnar maps in primates.The system-level chaptersfocus on the oculomotor system VLSI models of early vision, schemas for high-level vision,goal-directed movements, modular learning, effects of applied electric current fields on corticalneural activity neuropsychological studies of brain and mind, and an information-theoretic view ofanalog representation in striate cortex.Eric L. Schwartz is Professor of Brain Research and ResearchProfessor of Computer Science, Courant Institute of Mathematical Sciences, New York UniversityMedical Center. Computational Neuroscience is included in the System Development FoundationBenchmark Series.