Biomaterials For Spinal Surgery

Author : Luigi Ambrosio
Publisher : Elsevier
ISBN 13 : 0857096192
Total Pages : 645 pages
Book Rating : 4.97/5 ( download)

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Download or read book Biomaterials for Spinal Surgery written by Luigi Ambrosio and published by Elsevier. This book was released on 2012-03-12 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients. After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration. With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice. Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patients Reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery Discusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty

Author : Kai-Uwe Lewandrowski
Publisher : CRC Press
ISBN 13 : 0824756894
Total Pages : 817 pages
Book Rating : 4.95/5 ( download)

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Download or read book Advances in Spinal Fusion written by Kai-Uwe Lewandrowski and published by CRC Press. This book was released on 2003-10-21 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds for cells. It captures a cascade of innovations crucial to increased healing and decreased morbidity in spinal fusion methods and mechanics and addresses current standards in analytical methodology and quality control, it describes the selection of biomaterials for improved biocompatibility, biostability, and structure/function relationships.

Author : R. Gunzburg
Publisher : Springer Science & Business Media
ISBN 13 : 9783540426875
Total Pages : 148 pages
Book Rating : 4.76/5 ( download)

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Download or read book The Use of Bone Substitutes in Spine Surgery written by R. Gunzburg and published by Springer Science & Business Media. This book was released on 2002 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in surgical techniques have led to an increased demand for bone stock. Fusion enhancement, bone-void filling in tumor surgery and trauma are only a few examples. Autologous bone can be considered as the most successful bone graft material, and constitutes the accepted 'gold standard', as it combines all the properties required from the bone graft. In this book a 'state of the art in bone substitution for the spine' is presented. The general principles of bone biology and bone healing are outlined, as are recent advances in understanding and influencing bone formation. A variety of substitutes are described and compared.

Author : Sibylle Grad
Publisher : Springer Nature
ISBN 13 : 3031025806
Total Pages : 96 pages
Book Rating : 4.08/5 ( download)

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Download or read book Cells and Biomaterials for Intervertebral Disc Regeneration written by Sibylle Grad and published by Springer Nature. This book was released on 2022-06-01 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration

Author : Sibylle Grad
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1608454649
Total Pages : 96 pages
Book Rating : 4.48/5 ( download)

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Download or read book Cells and Biomaterials for Intervertebral Disc Regeneration written by Sibylle Grad and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration

Author : Regis W. Haid
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805574312
Total Pages : 333 pages
Book Rating : 4.10/5 ( download)

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Download or read book Advances in Spinal Stabilization written by Regis W. Haid and published by Karger Medical and Scientific Publishers. This book was released on 2003-01-01 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keep up-to-date in this fast moving field Dramatic changes in spinal stabilization have taken place in the last years and the pace of change continues to accelerate. This volume is an excellent mirror of the evolution of spinal stabilization. It brings together the latest and most comprehensive reviews in minimally-invasive and novel surgical approaches and spinal stabilization techniques. Highlights in new biomaterials including radiolucent, bioresorbable, and standard titanium are discussed by experts. Biological advances including the use of bone morphogenetic protein in anterior lumbar interbody fusion as well as computer-assisted image-guided surgical techniques are demonstrated. The section on instrumentation and technique represents the most up-to-date advances in surgical technique and management of spinal disorders. Illustrations included in each chapter document these excellent papers. Because it is a must for all surgeons performing spinal surgery to keep up-to-date in this fast moving field this book is indispensable reading for them. Neurosurgeons and orthopedic surgeons will find a wealth of information in this volume on the developments in surgical approaches, biomaterials and implants, and biological innovations.

Author : Dominique G. Poitout
Publisher : Springer
ISBN 13 : 1848826648
Total Pages : 547 pages
Book Rating : 4.49/5 ( download)

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Download or read book Biomechanics and Biomaterials in Orthopedics written by Dominique G. Poitout and published by Springer. This book was released on 2016-06-15 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.

Author : J. A. Planell
Publisher : Elsevier
ISBN 13 : 1845696611
Total Pages : 492 pages
Book Rating : 4.10/5 ( download)

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Download or read book Bone Repair Biomaterials written by J. A. Planell and published by Elsevier. This book was released on 2009-08-26 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone repair is a fundamental part of the rapidly expanding medical care sector and has benefited from many recent technological developments. With an increasing number of technologies available, it is vital that the correct technique is selected for specific clinical procedures. This unique book will provide a comprehensive review of the materials science, engineering principles and recent advances in this important area. The first part of the book reviews the fundamentals of bone repair and regeneration. Chapters in the second part discuss the science and properties of biomaterials used for bone repair such as metals, ceramics, polymers and composites. The final section of the book discusses clinical applications and considerations with chapters on such topics as orthopaedic surgery, tissue engineering, implant retrieval and ethics of bone repair biomaterials. With its distinguished editors and team of international contributors, Bone repair biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Reviews the fundamentals of bone repair and regeneration addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair with specific chapters assessing metals, ceramics, polymers and composites

Author : Kai-Uwe Lewandrowski
Publisher : CRC Press
ISBN 13 : 9781135525415
Total Pages : 815 pages
Book Rating : 4.12/5 ( download)

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Download or read book Advances in Spinal Fusion written by Kai-Uwe Lewandrowski and published by CRC Press. This book was released on 2003-10-21 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds for cells. It captures a cascade of innovations crucial to increased healing and decreased morbidity in spinal fusion methods and mechanics and addresses current standards in analytical methodology and quality control, it describes the selection of biomaterials for improved biocompatibility, biostability, and structure/function relationships.

Author : Mitsuo Niinomi
Publisher : Elsevier
ISBN 13 : 1845699246
Total Pages : 439 pages
Book Rating : 4.46/5 ( download)

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Download or read book Metals for Biomedical Devices written by Mitsuo Niinomi and published by Elsevier. This book was released on 2010-03-31 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in medical devices using other materials, metallic implants are still one of the most commercially significant sectors of the industry. Given the widespread use of metals in medical devices, it is vital that the fundamentals and behaviour of this material are understood. Metals in biomedical devices reviews the latest techniques in metal processing methods and the behaviour of this important material. Initial chapters review the current status and selection of metals for biomedical devices. Chapters in part two discuss the mechanical behaviour, degradation and testing of metals with specific chapters on corrosion, wear testing and biocompatibility of biomaterials. Part three covers the processing of metals for biomedical applications with chapters on such topics as forging metals and alloys, surface treatment, coatings and sterilisation. Chapters in the final section discuss clinical applications of metals such as cardiovascular, orthopaedic and new generation biomaterials. With its distinguished editor and team of expert contributors, Metals for biomedical devices is a standard reference for materials scientists, researchers and engineers working in the medical devices industry and academia. Reviews the latest techniques in metal processing methods including surface treatment and sterilisation Examines metal selection for biomedical devices considering biocompatibility of various metals Assesses mechanical behaviour and testing of metals featuring corrosion, fatigue and wear