Biomaterial Based Approaches To Study The Tumour Microenvironment

Author : Jessica O Winter
Publisher : Royal Society of Chemistry
ISBN 13 : 1839166029
Total Pages : 376 pages
Book Rating : 4.20/5 ( download)

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Download or read book Biomaterial Based Approaches to Study the Tumour Microenvironment written by Jessica O Winter and published by Royal Society of Chemistry. This book was released on 2022-12-07 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumour microenvironment is increasingly recognized as an important contributor to cancer progression and treatment. However, most cancer studies continue to be performed in 2D tissue culture dishes that do not capture the characteristics of the tumour niche. This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies, including scaffold design and synthesis, chemical signalling and delivery, and co-culture, microfluidics, and organ-on-a-chip tools that can be used to mimic tumour microenvironment features. This book also includes discussion of emerging imaging methods compatible with tumour microenvironment mimicking biomaterials and discusses applications of such models in immuno-oncology, metastasis, and drug screening. Edited by two leaders in the field, this book will appeal to graduate students and researchers working in biomaterials science, chemical and biomedical engineering departments.

Author : Josie Ursini-Siegel
Publisher : Springer Nature
ISBN 13 : 107162914X
Total Pages : 417 pages
Book Rating : 4.47/5 ( download)

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Download or read book The Tumor Microenvironment written by Josie Ursini-Siegel and published by Springer Nature. This book was released on 2023-01-01 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides update and new chapters detailing core and emerging in vitro and in vivo protocols. Chapters guide readers through cellular and molecular biology approaches, in vivo genetic approaches, various “omics”-based strategies, therapeutic strategies, and advanced techniques in the fields of tissue engineering and nanotechnology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, The Tumor Microenvironment: Methods and Protocols, Second Edition is a valuable resource for both novice and expert scientists in this developing field.

Author : Subhas C. Kundu
Publisher : Elsevier
ISBN 13 : 012818129X
Total Pages : 773 pages
Book Rating : 4.94/5 ( download)

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Download or read book Biomaterials for 3D Tumor Modeling written by Subhas C. Kundu and published by Elsevier. This book was released on 2020-08-22 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine. Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery

Author : Helena S. Azevedo
Publisher : Woodhead Publishing
ISBN 13 : 0081020120
Total Pages : 612 pages
Book Rating : 4.28/5 ( download)

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Download or read book Self-assembling Biomaterials written by Helena S. Azevedo and published by Woodhead Publishing. This book was released on 2018-04-17 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. Explores both theoretical and practical aspects of self-assembly in biomaterials Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials Examines the use of dynamic self-assembling biomaterials

Author : Glenn Dranoff
Publisher : Springer Science & Business Media
ISBN 13 : 3642141366
Total Pages : 313 pages
Book Rating : 4.62/5 ( download)

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Download or read book Cancer Immunology and Immunotherapy written by Glenn Dranoff and published by Springer Science & Business Media. This book was released on 2011-04-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.

Author : Kuruvilla Joseph
Publisher : Royal Society of Chemistry
ISBN 13 : 1839165359
Total Pages : 291 pages
Book Rating : 4.51/5 ( download)

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Download or read book Lignin-based Materials written by Kuruvilla Joseph and published by Royal Society of Chemistry. This book was released on 2023-06-14 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a neat overview of the current research for the biomaterials science community, this book is a one-stop resource for researchers and practitioners working on lignin-based biomaterials..

Author : Cheng Dong
Publisher : Springer
ISBN 13 : 3319952943
Total Pages : 376 pages
Book Rating : 4.49/5 ( download)

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Download or read book Biomechanics in Oncology written by Cheng Dong and published by Springer. This book was released on 2018-10-27 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer

Author : Sam Thiagalingam
Publisher : Cambridge University Press
ISBN 13 : 0521493390
Total Pages : 597 pages
Book Rating : 4.90/5 ( download)

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Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Author : Jagan Mohan Dodda
Publisher : Royal Society of Chemistry
ISBN 13 : 1839167270
Total Pages : 677 pages
Book Rating : 4.70/5 ( download)

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Download or read book Multicomponent Hydrogels written by Jagan Mohan Dodda and published by Royal Society of Chemistry. This book was released on 2023-05-22 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book critically discusses the fundamental chemistry, synthesis, characterisation, physiochemical and biological properties of various types of multicomponent hydrogels. It reviews the different strategies employed in designing and synthesizing cutting-edge multicomponent hydrogels and their key applications in biomedical fields.

Author : Khalid S. Essa
Publisher : BoD – Books on Demand
ISBN 13 : 1803556706
Total Pages : 138 pages
Book Rating : 4.03/5 ( download)

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Download or read book Electrospinning written by Khalid S. Essa and published by BoD – Books on Demand. This book was released on 2024-04-24 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrospinning - Theory, Applications, and Update Challenges is a comprehensive guide that delves into the principles, techniques, and applications of this cutting-edge technology. Electrospinning, a versatile and innovative process, has revolutionized industries such as health care, textiles, and materials science. The first section presents a detailed overview of electrospinning, covering topics ranging from the fundamentals of electrostatics and polymer science to advanced electrospinning techniques and industrial applications. The second section covers the intricacies of fiber formation, the influence of process parameters, and the wide array of materials that can be spun into fibers. The book provides valuable insights into the latest developments and future prospects of electrospinning.