Book Synopsis Biological Reactive Intermediates VI. by :
Download or read book Biological Reactive Intermediates VI. written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Biological Reactive Intermediates Vi
Download Biological Reactive Intermediates Vi full books in PDF, epub, and Kindle. Read online Biological Reactive Intermediates Vi ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Biological Reactive Intermediates Vi
Author : Patrick M. Dansette
Publisher : Springer Science & Business Media
ISBN 13 : 1461506670
Total Pages : 716 pages
Book Rating : 4.76/5 ( download)
Book Synopsis Biological Reactive Intermediates Vi by : Patrick M. Dansette
Download or read book Biological Reactive Intermediates Vi written by Patrick M. Dansette and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, recent advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair, tissue specific responses to BRIs, and human health effects of BRIs. The papers that comprise this volume were submitted by world class scientists who were in attendance at The Symposium on Biological Reactive Intermediates VI at the Université René Descartes, July 16-20, 2000.
Biological Reactive Intermediates—II
Author : Robert Snyder
Publisher : Springer
ISBN 13 : 147570674X
Total Pages : 844 pages
Book Rating : 4.41/5 ( download)
Book Synopsis Biological Reactive Intermediates—II by : Robert Snyder
Download or read book Biological Reactive Intermediates—II written by Robert Snyder and published by Springer. This book was released on 2014-11-14 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Biological Reactive Intermediates IV
Author : Charlotte M. Witmer
Publisher : Springer Science & Business Media
ISBN 13 : 1468458779
Total Pages : 848 pages
Book Rating : 4.70/5 ( download)
Book Synopsis Biological Reactive Intermediates IV by : Charlotte M. Witmer
Download or read book Biological Reactive Intermediates IV written by Charlotte M. Witmer and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated a meeting by a small group of toxicologists at the University of Turku, in Finland, in 1975 (Jollow et al. , 1977). The growing interest in this field of research led to subsequent symposia at the University of Surrey, in England in 1980 (Snyder et al. , 1982), and the University of Maryland in the U. S. A. in 1985 (Kocsis et al. , 1986). The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicology at the University of Arizona and convened in Tucson, Arizona, January 14-17, 1990. Over 300 people attended. There were 60 platform presentations by invited speakers, and 96 volunteer communications in the form of posters were offered. These meetings have grown from a small group of scientists working in closely related areas to a major international series of symposia which convene every five years to review, and place in context, the latest advances in our understanding of the formation, fate and consequences of biological reactive intermediates. The Organizing Committee: Allan H. Conney, Robert Snyder (Co-chairman), and Charlotte M. Witmer (Rutgers University, Piscataway, NJ), David J. Jollow Co chairman) (Medical University, South Carolina, Charleston, SC), 1. Glenn Sipes (Co chairman) (University of Arizona, Tucson, AZ), James J. Kocsis and George F.
Biological reactive Intermediates
Book Synopsis Biological reactive Intermediates by :
Download or read book Biological reactive Intermediates written by and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Biological Reactive Intermediates III
Author :
Publisher :
ISBN 13 :
Total Pages : 1059 pages
Book Rating : 4.00/5 ( download)
Book Synopsis Biological Reactive Intermediates III by :
Download or read book Biological Reactive Intermediates III written by and published by . This book was released on 1986 with total page 1059 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Biological Reactive Intermediates II
Author : Robert Snyder
Publisher :
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.53/5 ( download)
Book Synopsis Biological Reactive Intermediates II by : Robert Snyder
Download or read book Biological Reactive Intermediates II written by Robert Snyder and published by . This book was released on 1981 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Biological Reactive Intermediates
Author : David Jollow
Publisher : Springer Science & Business Media
ISBN 13 : 1461341248
Total Pages : 513 pages
Book Rating : 4.46/5 ( download)
Book Synopsis Biological Reactive Intermediates by : David Jollow
Download or read book Biological Reactive Intermediates written by David Jollow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept that detoxication is the inevitable result of biotransformation of xenobiotic compounds by mammalian systems has undergone modification since it was first described. Indeed, despite the fact that R. T. Williams popularized the notion, he was among the first to caution that it was not possible to predict the biological activities of the resulting metabolites. It has become increasingly apparent in recent years that not only do many metabolites of drugs and other chemicals display biological activity but also in many instances these metabolites play an important role in initiating several forms of cancer and are the cause of a variety of types of toxicity. Thus it seems appropriate to collect in one volume a series of reports outlining advances in the study of the formation of chemically active intermediary metabolic products of chemicals, mechanisms of toxicity or carcinogenesis, and pathways for true detoxication of these chemicals. The work of R. T. Williams, beginning in the late 1920s and early 1930s, marked the first concerted effort to understand the biotransformation of foreign chemicals in animals. He investigated the metabolic pathway of numerous compounds in a wide variety of animal species while training large numbers of our colleagues who have been responsible for further advances in biochemistry, pharmacology, and toxicology. Another pioneer in the study of drug metabo lism, B. B.
Biological Reactive Intermediates II
Author :
Publisher :
ISBN 13 :
Total Pages : 1476 pages
Book Rating : 4.03/5 ( download)
Book Synopsis Biological Reactive Intermediates II by :
Download or read book Biological Reactive Intermediates II written by and published by . This book was released on 1982 with total page 1476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Biological Reactive Intermediates V
Author : Robert R. Snyder
Publisher : Springer
ISBN 13 : 9781475794823
Total Pages : 462 pages
Book Rating : 4.27/5 ( download)
Book Synopsis Biological Reactive Intermediates V by : Robert R. Snyder
Download or read book Biological Reactive Intermediates V written by Robert R. Snyder and published by Springer. This book was released on 2013-06-26 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam ples of enzymatically catalyzed reactions in which normal body constituents can be linked through covalent bonds during the process of intermediary metabolism. The finding that xenobiotic chemicals that enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects was an observation that spawned the research featured in the Fifth International Symposium on Biological Reactive Intermediates (BRI V). The group of investigators that became fascinated with this process and its signifi cance in terms of human health began their discussions in Turku, Finland (J 975), and continued them at Guildford, England (1980), College Park, Maryland (1985), Tucson, Arizona (1990), and Munich, Germany (1995). Among the results were a series of reports listed below, as well as the book for which this serves as the Preface. • Jollow, DJ., Kocsis, J.J., Snyder, R. and Vainio, H. (eds), Biological Reactive Intermediates: Formation, Toxicity and Inactivation, Plenum Press, NY, 1975. • Snyder, R., Park, D.V., Kocsis, J.J., Jollow, D.V., Gibson, G.G. and Witmer, C.M. (eds), Biological Reactive Intermediates II: Chemical Mechanisms and Biological Effects, Plenum Press, N.Y., 1982.
