Benign And Pathological Chromosomal Imbalances

Author : Thomas Liehr
Publisher : Academic Press
ISBN 13 : 0124046843
Total Pages : 227 pages
Book Rating : 4.49/5 ( download)

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Download or read book Benign and Pathological Chromosomal Imbalances written by Thomas Liehr and published by Academic Press. This book was released on 2013-08-31 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Benign & Pathological Chromosomal Imbalances systematically clarifies the disease implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic assessment of heterochromatic or euchromatic DNA variants. While variants of several megabasepair can be present in the human genome without clinical consequence, visually distinguishing these benign areas from disease implications does not always occur to practitioners accustomed to costly molecular profiling methods such as FISH, aCGH, and NGS. As technology-driven approaches like FISH and aCGH have yet to achieve the promise of universal coverage or cost efficacy to sample investigated, deep chromosome analysis and molecular cytogenetics remains relevant for technology translation, study design, and therapeutic assessment. Knowledge of the rare but recurrent rearrangements unfamiliar to practitioners saves time and money for molecular cytogeneticists and genetics counselors, helping to distinguish benign from harmful CG-CNV. It also supports them in deciding which molecular cytogenetics tools to deploy. Shows how to define the inheritance and formation of cytogenetically visible copy number variations using cytogenetic and molecular approaches for genetic diagnostics, patient counseling, and treatment plan development Uniquely classifies all known variants by chromosomal origin, saving time and money for researchers in reviewing benign and pathologic variants before costly molecular methods are used to investigate Side-by-side comparison of copy number variants with their recently identified submicroscopic form, aiding technology assessment using aCGH and other techniques

Author : Marta C. Cohen
Publisher : Cambridge University Press
ISBN 13 : 1316124150
Total Pages : 1225 pages
Book Rating : 4.54/5 ( download)

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Download or read book Essentials of Surgical Pediatric Pathology written by Marta C. Cohen and published by Cambridge University Press. This book was released on 2015-02-05 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Surgical Pediatric Pathology is a clear and practical yet comprehensive guide for trainee pediatric pathologists and non-pediatric pathologists. Each chapter corresponds to one of the main subspecialties, such as dermatopathology, head and neck pathology, and system pathology. Practical guidance is given on handling pediatric specimens and the authors highlight the ways in which common conditions present differently in adults and children. Other chapters cover conditions typical of childhood, including soft tissue tumors and blue round cell tumors. The chapters begin with a brief clinical presentation, followed by a clear macroscopical and histological description of the principal pathologies seen in children. Up-to-date genetic and immunohistochemical information is provided, and the book includes hundreds of high-quality color images. Written and edited by leading international experts in the field, this is an essential resource for trainee pediatric pathologists, as well as general pathologists who may encounter pediatric cases.

Author : Raymond W. Redline
Publisher : Cambridge University Press
ISBN 13 : 1316632539
Total Pages : 367 pages
Book Rating : 4.36/5 ( download)

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Download or read book Placental and Gestational Pathology with Online Resource written by Raymond W. Redline and published by Cambridge University Press. This book was released on 2018-08-23 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.

Author : Stéphane Viville
Publisher : Cambridge University Press
ISBN 13 : 100919772X
Total Pages : 255 pages
Book Rating : 4.24/5 ( download)

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Download or read book Textbook of Human Reproductive Genetics written by Stéphane Viville and published by Cambridge University Press. This book was released on 2022-12-31 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

Author : Robert O. Greer
Publisher : Cambridge University Press
ISBN 13 : 1316613992
Total Pages : 607 pages
Book Rating : 4.93/5 ( download)

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Download or read book Pediatric Head and Neck Pathology written by Robert O. Greer and published by Cambridge University Press. This book was released on 2017-07-06 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference for tackling diagnostic dilemmas that pathologists and clinicians encounter when assessing pediatric head and neck disease.

Author : Luis Requena
Publisher : Springer
ISBN 13 : 3319457047
Total Pages : 1052 pages
Book Rating : 4.48/5 ( download)

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Download or read book Cutaneous Adnexal Neoplasms written by Luis Requena and published by Springer. This book was released on 2017-12-28 with total page 1052 pages. Available in PDF, EPUB and Kindle. Book excerpt: This superbly illustrated book is the most comprehensive available guide to adnexal neoplasms of the skin. More than 70 entities are described in individual chapters that follow a uniform structure: historical review, clinical features, histopathology, histogenesis, immunohistochemistry, molecular anomalies, and treatment. Readers will find state of the art knowledge on all aspects, including the cytogenetic and chromosomal abnormalities associated with each neoplasm. Without exception, the illustrations are high-quality, full-color, original digital pictures. The histopathology images are taken from perfectly cut and stained sections and the immunohistochemistry illustrations are of an unrivalled quality among textbooks of dermatology and dermatopathology. A complete list of references from original description to the present day is also supplied for each neoplasm. Cutaneous adnexal neoplasms are a large and heterogeneous group of benign and malignant lesions. This book will assist the reader in early and correct recognition, which is essential for appropriate choice of treatment and prognostic assessment.

Author : Marcelo Larramendy
Publisher : BoD – Books on Demand
ISBN 13 : 9535134736
Total Pages : 206 pages
Book Rating : 4.32/5 ( download)

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Download or read book Chromosomal Abnormalities written by Marcelo Larramendy and published by BoD – Books on Demand. This book was released on 2017-08-30 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book, Chromosomal Abnormalities - A Hallmark Manifestation of Genomic Instability, contains a series of chapters highlighting several aspects related to the generation of chromosomal abnormalities in genetic material. We are extremely grateful to the authors who had contributed with valuable information about the role of genomic instability in pathological disorders as well as in the evolution process.

Author :
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.23/5 ( download)

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Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : R.J. MKinlay Gardner
Publisher : OUP USA
ISBN 13 : 0195375335
Total Pages : 650 pages
Book Rating : 4.36/5 ( download)

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Download or read book Chromosome Abnormalities and Genetic Counseling written by R.J. MKinlay Gardner and published by OUP USA. This book was released on 2012 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cytogenetics continue to crop up in wonderful ways, and we know exponentially more about chromosomes now than mere decades ago. Likewise, the necessary skills in offering genetic counseling continue to evolve. This new edition of Chromosome Abnormalities in Genetic Counseling offers a practical, up-to-date guide for the genetic counselor to marshal cytogenetic data and analysis clearly and effectively to families.

Author : Ancel Blaustein
Publisher : Springer Science & Business Media
ISBN 13 : 1441904883
Total Pages : 1261 pages
Book Rating : 4.81/5 ( download)

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Download or read book Blaustein's Pathology of the Female Genital Tract written by Ancel Blaustein and published by Springer Science & Business Media. This book was released on 2011-01-10 with total page 1261 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition includes more than 350 new illustrations and 22 revised chapters Written by internationally recognized experts Each entry is structured the same way, from general to more specific information, which allows the reader to quickly access key information in every chapter Since the publication of the 1/e in 1977, Blaustein's Pathology of the Female Genital Tract has consolidated its position as the leading textbook of gynecological pathology. an essential reference for all pathologists and residents, this thoroughly updated Sixth Edition includes more than 1500 illustrations in color, i