Bacterial Epithelial Cell Cross Talk

Author : Beth A. McCormick
Publisher : Cambridge University Press
ISBN 13 : 1139458280
Total Pages : 415 pages
Book Rating : 4.83/5 ( download)

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Download or read book Bacterial-Epithelial Cell Cross-Talk written by Beth A. McCormick and published by Cambridge University Press. This book was released on 2006-09-07 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: An emerging theme in molecular and cellular microbiology has been the ability of many pathogens to usurp the host cell and eventually colonize the host. This interaction between bacteria and host is not unidirectional - both pathogens and host cells engage in a signalling cross-talk. Research focused on this cross-talk and discussed in this volume, reveals not only novel aspects of bacterial pathogenesis, but also key information about epithelial biology with broader implications in the prevention and treatment of infectious diseases. Written by leading researchers in this field, this book provides a valuable overview of the host-bacterial interactions that occur at mucosal surfaces including the gastrointestinal, respiratory, and urogenital tracts. It will therefore be a valuable resource for graduate students and researchers working on these systems or in the fields of molecular and cellular microbiology or infectious disease medicine.

Author : Beth A. McCormick
Publisher :
ISBN 13 : 9780511245985
Total Pages : 439 pages
Book Rating : 4.8X/5 ( download)

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Download or read book Bacterial-epithelial Cell Cross-talk written by Beth A. McCormick and published by . This book was released on 2006 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Britta Siegmund
Publisher : Frontiers Media SA
ISBN 13 : 2889456188
Total Pages : 159 pages
Book Rating : 4.85/5 ( download)

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Download or read book Immune-Epithelial Crosstalk in Inflammatory Bowel Diseases and Mucosal Wound Healing written by Britta Siegmund and published by Frontiers Media SA. This book was released on 2018-10-18 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.91/5 ( download)

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Download or read book Immune-Epithelial Crosstalk in Inflammatory Bowel Diseases and Mucosal Wound Healing written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: 80% of the bodies' immune cells are harbored within the intestine. They are only separated from 1014 microorganisms by a single layer of intestinal epithelial cells and a secreted superficial mucus layer. Therefore, the intestinal epithelial surface represents a main frontier in host defense. Providing an intact mucosal barrier is vital for the host to limit bacterial entry and spread to the circulation. This specialized localization requires dynamic responses of intestinal epithelial cells to both pathogen- and immune-derived signals. Moreover, emergency barriers are needed in the setting of epithelial damage, which allow provisional microbial control and a timely restitution of mucosal integrity. Epithelial cells constantly interact with subjacent immune cells and fibroblasts, actively directing the immune response and also shaping the luminal microbiota. Epithelial dysfunction has been appreciated in recent years as a driving element in the pathogenesis of Inflammatory Bowel Diseases (IBD). Additionally, primary immune deficiencies may manifest in the form of chronic intestinal inflammation mimicking features of IBD. Recent advances in the techniques of epithelial cell culture and the discovery of new immune cell types and cellular properties have tremendously advanced the understanding in this interesting field of research. In this research topic, we want to focus on the complex interaction of intestinal epithelial cells, luminal flora and adjacent immune cells and invite manuscripts which highlight the dynamic responses of both epithelium and immune cells under steady-state or inflammatory conditions, and envision how this may be translated to the benefit of patient-care.

Author : Nadeem Khan
Publisher : Frontiers Media SA
ISBN 13 : 288966175X
Total Pages : 115 pages
Book Rating : 4.56/5 ( download)

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Download or read book Cross-Talk Between Inflammation and Barrier Framework at Mucosal Surfaces in the Lung: Implications for Infections and Pathology written by Nadeem Khan and published by Frontiers Media SA. This book was released on 2020-12-16 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.81/5 ( download)

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Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Kitty Verhoeckx
Publisher : Springer
ISBN 13 : 3319161040
Total Pages : 338 pages
Book Rating : 4.44/5 ( download)

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Download or read book The Impact of Food Bioactives on Health written by Kitty Verhoeckx and published by Springer. This book was released on 2015-04-29 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.

Author : Lidija Cakarova
Publisher : Sudwestdeutscher Verlag Fur Hochschulschriften AG
ISBN 13 : 9783838111865
Total Pages : 88 pages
Book Rating : 4.69/5 ( download)

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Download or read book Alveolar Epithelial Repair in Gram Negative Bacterial Pneumonia written by Lidija Cakarova and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2009-11 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Damaged alveolar barrier and impaired gas exchange are the major hallmarks of pulmonary infection. Consequently, epithelial repair processes are initiated to restore the normal lung homeostasis. In the present thesis it was investigated whether early activated alveolar macrophages (AMf) contribute to alveolar epithelial repair following infection. LPS-activated AMf stimulated alveolar epithelial cells (AEC) to express growth factors, particularly GM-CSF in co-culture, in a TNF-alpha dependent manner. GM-CSF in turn elicited autocrine proliferative signalling in AEC. Notably, intra-alveolar TNF-alpha neutralization impaired AEC proliferation in LPS-injured mice in vivo. GM-CSF-deficient mice displayed reduced AEC proliferation and sustained alveolar barrier dysfunction upon LPS injury. Similarly, K. pneumoniae lung infection resulted in early release of macrophage TNF-alpha and epithelial GM-CSF, and subsequent TNF- -dependent AEC proliferation during alveolar repair. These findings indicate that TNF-alpha from activated AMf induces epithelial GM-CSF expression, which in turn initiates AEC proliferation and thus contributes to restore alveolar barrier function."

Author : W. Allan Walker
Publisher : Academic Press
ISBN 13 : 1483273490
Total Pages : 475 pages
Book Rating : 4.95/5 ( download)

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Download or read book Immunophysiology of the Gut written by W. Allan Walker and published by Academic Press. This book was released on 2013-10-22 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bristol-Myers Squibb/Mead Johnson Nutrition Symposia, Volume 11: Immunophysiology of the Gut represents a comprehensive and systematic coverage of the immunophysiology of the gut, compiling research that integrates the mucosal immune system and intestinal physiology. This book discusses the immunological regulation of epithelial function, fibroblastic sheath, pathways of arachidonic acid metabolism, and gastric response to mucosal anaphylaxis. The implications for inflammatory diarrhea, role of breast milk in neonatal host defense, and milk-borne peptide growth factors in human and bovine milk are also elaborated. This publication likewise covers the immunopathologic features of celiac disease, immune responses in protein-energy malnutrition, and bacterial translocation. This volume is suitable for experts and clinicians from the disciplines of mucosal immunology, intestinal physiology, and enteric neurophysiology.

Author : Anil Shanker
Publisher : Frontiers Media SA
ISBN 13 : 2889634140
Total Pages : 329 pages
Book Rating : 4.49/5 ( download)

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Download or read book Lymphocyte Functional Crosstalk and Regulation written by Anil Shanker and published by Frontiers Media SA. This book was released on 2020-01-20 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: