Autoimmune Diseases A Pathophysiological Approach

Author : Dallas Lynch
Publisher : Hayle Medical
ISBN 13 : 9781632415875
Total Pages : 291 pages
Book Rating : 4.79/5 ( download)

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Download or read book Autoimmune Diseases: A Pathophysiological Approach written by Dallas Lynch and published by Hayle Medical. This book was released on 2019-06-19 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune disease is the clinical condition that arises due to an abnormal immune response to a body part. There are around 80 different kinds of autoimmune diseases. Certain common autoimmune diseases are diabetes mellitus type 1, psoriasis, rheumatoid arthritis, multiple sclerosis, etc. The diagnosis of an autoimmune disease can be difficult to determine and depends on the type of the condition or its severity. Autoimmune diseases may have certain pathological effects such as damage or destruction of tissues and altered organ function or organ growth. They may evolve into chronic, debilitating and even life-threatening conditions in some cases. The treatment of an autoimmune disease generally targets the symptoms rather than the disease itself as the causative factor is still not defined. Immunosuppressants, nonsteroidal anti-inflammatory drugs (NSAIDs) and intravenous immunoglobulin are commonly used for treatment. This book explores all the important aspects of autoimmune diseases in modern day healthcare. It strives to provide a fair idea about the diagnosis and treatment of autoimmune diseases and to help develop a better understanding of the latest advances in this area. This book will serve as a reference to a broad spectrum of readers.

Author : Udi Nussinovitch
Publisher : Academic Press
ISBN 13 : 0128032685
Total Pages : 766 pages
Book Rating : 4.88/5 ( download)

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Download or read book The Heart in Rheumatic, Autoimmune and Inflammatory Diseases written by Udi Nussinovitch and published by Academic Press. This book was released on 2017-02-10 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

Author : Michael Hertl
Publisher : Springer Science & Business Media
ISBN 13 : 3709137047
Total Pages : 365 pages
Book Rating : 4.48/5 ( download)

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Download or read book Autoimmune Diseases of the Skin written by Michael Hertl and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous autoimmune diseases are often chronic and severe conditions which remain an enigma for many clinicians. Experts in the field here provide a practical guide to identifying and handling these conditions. Unique in its attention to the pathophysiology, clinical diagnosis, and management of these disorders, this book is illustrated with many tables, illustrative figures and clinical color photographs. The chief aim is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and manage these conditions.

Author : Tomohiro Kurosaki
Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 231 pages
Book Rating : 4.31/5 ( download)

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Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

Author : Robert George Lahita
Publisher :
ISBN 13 : 9780781715058
Total Pages : 883 pages
Book Rating : 4.59/5 ( download)

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Download or read book Textbook of the Autoimmune Diseases written by Robert George Lahita and published by . This book was released on 2000 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of the Autoimmune Diseases is the definitive reference work about the mechanisms autoimmune diseases employ against the body and the conditions in which they thrive. Whether it's where and how autoimmune diseases disable organs from functioning, or the first symptoms of disease, this book blends both the clinical and the scientific to explain autoimmune diseases' phenomena. The only source for information on heavy metals' and silicone implants' effects on autoimmunity, this book compiles contributions from world-renowned faculty to cut across all fields of medicine, from surgery to internal medicine.

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.70/5 ( download)

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Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : R.C. Kennedy
Publisher : Elsevier
ISBN 13 : 0080534430
Total Pages : 557 pages
Book Rating : 4.35/5 ( download)

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Download or read book Idiotypes in Medicine: Autoimmunity, Infection and Cancer written by R.C. Kennedy and published by Elsevier. This book was released on 1997-11-19 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Author :
Publisher : Elsevier
ISBN 13 : 0444634460
Total Pages : 568 pages
Book Rating : 4.67/5 ( download)

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Download or read book Autoimmune Neurology written by and published by Elsevier. This book was released on 2016-03-11 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Author : Marcy Ward
Publisher :
ISBN 13 : 9781646475704
Total Pages : 0 pages
Book Rating : 4.04/5 ( download)

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Download or read book Autoimmune Diseases: Diagnosis, Pathophysiology and Treatment written by Marcy Ward and published by . This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An autoimmune disease refers to a type of medical condition caused by an abnormal immune response to a healthy body part. The most common types of autoimmune diseases include rheumatoid arthritis (RA), multiple sclerosis, celiac disease, type 1 diabetes, systemic lupus erythematosus (SLE), myasthenia gravis, and inflammatory bowel disease. Majority of the autoimmune diseases share similar signs and symptoms, such as sore muscles, low-grade fever, skin rashes and exhaustion. There are many risk factors associated with autoimmune diseases, such as family history, obesity, smoking and exposure to pollutants. Autoimmune diseases can be diagnosed by performing some blood tests, such as the erythrocyte sedimentation rate (ESR), antinuclear antibody test (ANA) and complete blood count (CBC). Treatment of these diseases is determined by the nature and severity of the condition. Immunosuppressants and nonsteroidal anti-inflammatory medications (NSAIDs) are frequently utilized for the treatment of autoimmune diseases. This book elucidates the innovative models around prospective developments with respect to autoimmune diseases. It is compiled in such a manner, that it will provide in-depth knowledge about the diagnosis, pathophysiology and treatment of these diseases. This book will prove to be immensely beneficial to students and researchers studying these diseases.

Author : Yehuda Shoenfeld
Publisher : Springer Science & Business Media
ISBN 13 : 1603272852
Total Pages : 593 pages
Book Rating : 4.58/5 ( download)

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Download or read book Diagnostic Criteria in Autoimmune Diseases written by Yehuda Shoenfeld and published by Springer Science & Business Media. This book was released on 2010-06-08 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.