Atkinsons Principles Of Clinical Pharmacology

Author : Shiew-Mei Huang
Publisher : Academic Press
ISBN 13 : 0128198842
Total Pages : 764 pages
Book Rating : 4.41/5 ( download)

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Download or read book Atkinson's Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2021-10-16 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Author : Arthur J. Atkinson, Jr.
Publisher : Elsevier
ISBN 13 : 9780080466422
Total Pages : 568 pages
Book Rating : 4.27/5 ( download)

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Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson, Jr. and published by Elsevier. This book was released on 2011-04-28 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Author : Shiew-Mei Huang
Publisher : Academic Press
ISBN 13 : 0123854725
Total Pages : 649 pages
Book Rating : 4.28/5 ( download)

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Download or read book Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2012-09-18 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III

Author : Scott A. Waldman
Publisher : Saunders
ISBN 13 : 9781416060987
Total Pages : 0 pages
Book Rating : 4.87/5 ( download)

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Download or read book Pharmacology and Therapeutics written by Scott A. Waldman and published by Saunders. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everything you need to know about all of today's drugs in a coherent, easy-to-use format - from the underlying science through innovation, translation, regulation, and clinical implementation. This multimedia resource fills a critical need for a more clinically focused, user-friendly pharmacology reference. Evidence-based therapeutic guidelines facilitate decision making; and coverage of pharmacogenetics and pharmacogenomics, regenerative pharmacology, stem cell therapies, and the emerging field of individualized medicine keeps you at the forefront of the latest developments.

Author : Sara E. Rosenbaum
Publisher : John Wiley & Sons
ISBN 13 : 1119143160
Total Pages : 576 pages
Book Rating : 4.61/5 ( download)

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Download or read book Basic Pharmacokinetics and Pharmacodynamics written by Sara E. Rosenbaum and published by John Wiley & Sons. This book was released on 2016-11-22 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)

Author : David Grahame Grahame-Smith
Publisher : Oxford University Press, USA
ISBN 13 : 9780192616753
Total Pages : 756 pages
Book Rating : 4.57/5 ( download)

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Download or read book Oxford Textbook of Clinical Pharmacology and Drug Therapy written by David Grahame Grahame-Smith and published by Oxford University Press, USA. This book was released on 1992 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Clinical Pharamcology and Drug Therapy provides medical students with a unique insight into why drugs have their effects. The basic principles of pharmacology as they affect the patient are preseented helping the reader to gain an understanding of the reational basisfor prescribing drugs and obtaining the optimum effect. This fully up-dated edition successfuly meets the needs of medical students taking courses in clinical pharmacology.

Author : Steven Atkinson
Publisher :
ISBN 13 : 9781683730088
Total Pages : 0 pages
Book Rating : 4.89/5 ( download)

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Download or read book Geriatric Pharmacology written by Steven Atkinson and published by . This book was released on 2016-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Geriatric Pharmacology: The Principles of Practice & Clinical Recommendations is the optimal guide for anyone seeking straightforward, concise and user-friendly information on medication dynamics for older adults. Fully revised and updated, this invaluable resource has become the go-to favorite for healthcare professionals. Here's what you'll find: Learn to manage medication combinations without causing harm How to safely prescribe opioids Avoiding the top 10 most dangerous geriatric drugs Practical guidelines to stop and start prescriptions Drug-drug interaction charts and strategies

Author : Arthur J. Atkinson
Publisher : Academic Press
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.61/5 ( download)

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Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson and published by Academic Press. This book was released on 2007 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. Offers an expanded regulatory section that addresses US and international issues and guidelines. Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.

Author : Anton Bespalov
Publisher : Springer Nature
ISBN 13 : 3030336565
Total Pages : 424 pages
Book Rating : 4.61/5 ( download)

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Download or read book Good Research Practice in Non-Clinical Pharmacology and Biomedicine written by Anton Bespalov and published by Springer Nature. This book was released on 2020-01-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Author : John I. Gallin
Publisher : Elsevier
ISBN 13 : 9780080489568
Total Pages : 448 pages
Book Rating : 4.67/5 ( download)

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Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research *Delves into data management and addresses how to collect data and use it for discovery *Contains valuable, up-to-date information on how to obtain funding from the federal government