Arrhythmic And Vascular Complications Of Coronavirus Disease 2019 Covid 19 An Issue Of Cardiac Electrophysiology Clinics Volume 14 1

Author : Domenico G. Della Rocca
Publisher : Elsevier
ISBN 13 : 9780323987318
Total Pages : 240 pages
Book Rating : 4.11/5 ( download)

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Download or read book Arrhythmic and Vascular Complications of Coronavirus Disease 2019 (Covid-19), an Issue of Cardiac Electrophysiology Clinics: Volume 14-1 written by Domenico G. Della Rocca and published by Elsevier. This book was released on 2022-03-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Domenico G. Della Rocca, Giovanni B. Forleo, and Andrea Natale bring their considerable expertise to the topic of Arrhythmic and Vascular Complications of Coronavirus Disease 2019 (COVID-19). Top experts in the field cover key topics such as prevalence and clinical implications of COVID-19 myocarditis; electrocardiographic and echocardiographic features of COVID-19 patients; imaging findings of COVID-19-related cardiovascular complications; the role of digital health during COVID-19 pandemic; and more. Contains 14 relevant, practice-oriented topics including prevalence, management, and outcomes of supraventricular arrhythmias in COVID-19 patients; prevalence, management, and outcomes of ventricular arrhythmias in COVID-19 patients; COVID-19 associated endothelial dysfunction and microvascular injury; COVID-19, acute myocardial injury, and infarction; and more. Provides in-depth clinical reviews on arrhythmic and vascular complications of COVID-19, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Domenico G. Della Rocca
Publisher : Elsevier Health Sciences
ISBN 13 : 032398732X
Total Pages : 153 pages
Book Rating : 4.25/5 ( download)

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Download or read book Arrhythmic and Vascular Complications of Coronavirus Disease 2019 (COVID-19) , An Issue of Cardiac Electrophysiology Clinics, E-Book written by Domenico G. Della Rocca and published by Elsevier Health Sciences. This book was released on 2022-03-03 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Domenico G. Della Rocca, Giovanni B. Forleo, and Andrea Natale bring their considerable expertise to the topic of Arrhythmic and Vascular Complications of Coronavirus Disease 2019 (COVID-19). Top experts in the field cover key topics such as prevalence and clinical implications of COVID-19 myocarditis; electrocardiographic and echocardiographic features of COVID-19 patients; imaging findings of COVID-19-related cardiovascular complications; the role of digital health during COVID-19 pandemic; and more. Contains 14 relevant, practice-oriented topics including prevalence, management, and outcomes of supraventricular arrhythmias in COVID-19 patients; prevalence, management, and outcomes of ventricular arrhythmias in COVID-19 patients; COVID-19 associated endothelial dysfunction and microvascular injury; COVID-19, acute myocardial injury, and infarction; and more. Provides in-depth clinical reviews on arrhythmic and vascular complications of COVID-19, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Fabian Sanchis-Gomar
Publisher : Elsevier
ISBN 13 : 0443190925
Total Pages : 290 pages
Book Rating : 4.26/5 ( download)

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Download or read book COVID-19’s Consequences on the Cardiovascular System written by Fabian Sanchis-Gomar and published by Elsevier. This book was released on 2024-04-04 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: COVID-19 Consequences on Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all the aspects related with the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications. Written by a team of experts, this book is a one-stop-shop reference for both healthcare professionals and researchers who require a comprehensive view into the deleterious effects of COVID-19 on the cardiovascular system, the relationship of cardiovascular risk factors with COVID-19 prognosis, and further insights on the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level. Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system, with its most common complications being arrhythmia, cardiac injury, fulminant myocarditis, heart failure and pulmonary embolism. Covers all the current scientific pieces of evidence about the effects of COVID-19 on the heart and cardiovascular system from both a basic and a clinical point of view. Discusses immediate, intermediate, and long-term complications of COVID-19 on the cardiovascular system. Includes studies conducted worldwide by well-known experts in related fields.

Author : Timothy D. Henry
Publisher : Elsevier Health Sciences
ISBN 13 : 0323961703
Total Pages : 139 pages
Book Rating : 4.07/5 ( download)

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Download or read book Covid-19, An Issue of Cardiology Clinics, E-Book written by Timothy D. Henry and published by Elsevier Health Sciences. This book was released on 2022-07-20 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Cardiology Clinics, guest editors Drs. Timothy D. Henry and Santiago Garcia bring their considerable expertise to the topic of COVID-19. Top experts in the field cover key topics such as prothrombotic effects of COVID-19; impact of the COVID-19 pandemic on acute myocardial infarction care; impact of the COVID-19 pandemic on cardiac arrest and emergency care; vaccine-related cardiovascular effects; and more. Contains 11 relevant, practice-oriented topics including cardiovascular manifestations of COVID-19; use and prognostic implications of cardiac biomarkers (Troponin); COVID-19: Insights from cardiac pathology; ACS in COVID-19; STEMI in COVID-19; and more. Provides in-depth clinical reviews on COVID-19, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Maciej Banach
Publisher : Springer Nature
ISBN 13 : 3031154789
Total Pages : 434 pages
Book Rating : 4.82/5 ( download)

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Download or read book Cardiovascular Complications of COVID-19 written by Maciej Banach and published by Springer Nature. This book was released on 2022-12-28 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology of SARS-CoV-2, the course of COVID-19, risk factors that worsen the disease in COVID-19 patients, clinical features of COVID-19 patients, COVID-19 cardiological complications, treatment, and prevention methods, and long-term cardiological aspects of COVID-19. Chapters provide the reader with a contemporary perspective on the emerging links between COVID-19 and cardiovascular disease. In addition, this volume discusses the clinical implications and therapeutic goals in patients with COVID-19 and cardiac complications, as well as possible therapeutic options. It also offers clear recommendations on how to manage (both non- and pharmacologically) to avoid the increased number of COVID-19 related deaths due to CVD and its risk factors. Cardiovascular Complications of COVID-19 will be the primary resource for physicians, residents, fellows, and nursed and medical students in the fields of cardiology and COVID-19/infectious diseases as well as healthcare providers that initiate preventive activities and dedicated programs.

Author : Fabian Sanchis-Gomar
Publisher : Elsevier
ISBN 13 : 0443190917
Total Pages : 288 pages
Book Rating : 4.19/5 ( download)

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Download or read book COVID-19's Consequences on the Cardiovascular System written by Fabian Sanchis-Gomar and published by Elsevier. This book was released on 2024-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common complications are arrhythmia, cardiac injury, fulminant myocarditis, heart failure, and pulmonary embolism. COVID-19’s Consequences on the Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all aspects related to the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications. Written by a team of experts, this book is a one-stop-shop reference for healthcare professionals and researchers who require a comprehensive view of the deleterious effects of COVID-19 on the cardiovascular system. It discusses the relationship of cardiovascular risk factors with COVID-19 prognosis. It offers further insights into the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level.

Author : Umair Mallick
Publisher : Springer Nature
ISBN 13 : 3030900657
Total Pages : 416 pages
Book Rating : 4.56/5 ( download)

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Download or read book Cardiovascular Complications of COVID-19 written by Umair Mallick and published by Springer Nature. This book was released on 2022-02-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels of cardiovascular and metabolic complications. A myriad of pathogenetic mechanisms has come to the surface. There is still much research required to define whether cardiovascular disease causes COVID-19 complications or that cardiovascular disease appears as a result of the infection and which mechanisms are responsible. With cardiovascular and metabolic diseases already at pandemic levels and expected to increase further, this book provides readers with an urgent and thorough analysis of this association. Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes provides answers to the increasing numbers of questions related to heart disease in COVID-19, highlighting the association between these pandemics and including risk factors, mechanisms and how these may impact diverse patients populations. It describes how COVID-19 impacts older patients and those with metabolic illnesses such as obesity and diabetes mellitus, while providing an overview of the observed gender dichotomy among patients. It therefore represents an essential resource not only for all cardiovascular physicians but also for any healthcare professionals managing patients with these diseases or those exploring COVID-19.

Author : Timothy D. Henry
Publisher : Elsevier Health Sciences
ISBN 13 : 0443183597
Total Pages : 137 pages
Book Rating : 4.91/5 ( download)

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Download or read book Covid-19, An Issue of Heart Failure Clinics, E-Book written by Timothy D. Henry and published by Elsevier Health Sciences. This book was released on 2023-03-02 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Author : Ozgur KARCIOGLU
Publisher : Bentham Science Publishers
ISBN 13 : 1681088215
Total Pages : 288 pages
Book Rating : 4.11/5 ( download)

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Download or read book Cardiac Care and COVID-19: Perspectives in Medical Practice written by Ozgur KARCIOGLU and published by Bentham Science Publishers. This book was released on 2021-08-24 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Care and COVID-19: Perspectives in Medical Practice is an accessible reference on diagnoses and treatment modalities for cardiac diseases in general, and emergency cardiac conditions to be more specific, with respect to the current COVID-19 pandemic. Chapters in the book give updated descriptions of common problems in emergency medicine and cardiovascular disease. Each chapter is dedicated to a specific cardiovascular disease and explains management principles, diagnostic procedures and therapy. Examples of medical cases have also been used to highlight complex issues to give a concrete understanding of the cardiac care in COVID-19 patients to the medical practitioner, whether they are involved in critical care or in outpatient clinics. Key Features: - Clinical guidelines for critical care and cardiovascular management of COVID-19 patients - Topic-based information about cardiovascular diseases - Covers a range of cardiovascular problems including myocarditis, arrhythmias, chest pain, acute coronary syndrome - Information on pulmonary embolism and associated problems - Reader friendly presentation - Case-based examples for explaining concepts The range of topics combined with the simple presentation make this an essential reference for healthcare workers in emergency medicine, cardiology and nursing. General physicians interested in the cardiovascular impact of COVID-19 will also benefit from the information provided in the book.

Author : Brittany Danielle Brumback
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.55/5 ( download)

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Download or read book Intrinsic Cardiac Effects of Severe Acute Respiratory Syndrome Coronavirus 2 in Coronavirus Disease 2019 written by Brittany Danielle Brumback and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac arrhythmias, particularly ventricular arrhythmias, can be life-threatening and caused by both congenital genetic mutations and acquired cardiac injury. My thesis work was originally focused on delineating the effects of genetic mutation-driven dysregulation of a protein called Hey2 in Brugada Syndrome, a complex disease characterized by a predisposition to dangerous arrhythmias originating in the right ventricular outflow tract. In response to the pandemic, my thesis work shifted toward understanding the mechanisms of cardiovascular injury in Coronavirus disease 2019 (COVID-19), which is associated with serious cardiovascular complications, including ventricular arrhythmias and sudden cardiac death as well as endothelial dysfunction and coagulopathies. While the main dissertation is focused on the COVID-19 work, the original Hey2 project is covered in a supplemental chapter. COVID-19 patients can present with serious and sometimes lethal cardiovascular manifestations of the disease. Patients with severe cases of COVID-19 often suffer ventricular arrhythmias and sudden cardiac death, leading to increased morbidity and mortality, especially for patients with predisposing cardiovascular diseases. There is also substantial clinical evidence of patients experiencing acute myocardial infarctions, which may be caused by either direct damage to the myocardium or from vascular dysfunction that leads to blood clots and ultimately occlusions. Currently, there is significant discussion in the field about whether this cardiac damage is being caused by direct viral infection of the heart or due to systemic inflammatory effects. Many groups have sought to determine whether it is likely that SARS-CoV-2 could directly infect the heart via the ACE2 receptor. SARS-CoV-2 utilizes the ACE2 receptor to bind to cellular membranes and enter susceptible cells. Many groups have performed single-cell RNA-sequencing studies have been performed on human hearts that indicate ACE2 RNA is expressed in multiple cell types in the heart, with pericytes having the highest expression. Pericytes are perivascular cells that are found in abundance in the microvasculature in all vascularized organs where they regulate numerous functions, including vessel growth, permeability, and contractility. Since pericytes play a critical role in supporting endothelial cells and maintaining vascular integrity, we and others hypothesized that pericytes may be a culprit for cardiovascular damage in COVID-19. In healthy vessels, intact endothelial junctions would prevent SARS-CoV-2 was reaching pericytes due to size exclusion. However, if vessels have compromised barriers due to diseases, such as diabetes, SARS-CoV-2 could cross the barrier and infect pericytes, which could then lead to endothelial cell activation and inflammation. This could in turn lead to the coagulopathies and infarcts that are being reported in COVID-19 patients. In my thesis work, I started by collaborating with Dr. Michael Diamond's lab to combine the expertise and resources necessary to study the intrinsic cardiac effects of SARS-CoV-2 in COVID-19. Together, we adapted the Rentschler lab's previously establish human organotypic cardiac slice culture methodology to evaluate cellular tropism of SARS-CoV-2 in explanted donor human hearts rejected from transplantation. We identified cardiac pericytes as a direct target of SARS-CoV-2 infection in organotypic cardiac slices and then collaborated with Dr. Kory Lavine's lab to further evaluate viral entry and downstream effects of infection in primary cardiac pericytes. We found that primary cardiac pericytes were productively infected by SARS-CoV-2; however, we determined that other types of primary human pericytes from other organs, including the brain and placenta, were not infected likely due to significantly lower expression of the main viral entry receptor, ACE2, compared to cardiac pericytes. Furthermore, we determined that viral entry into cardiac pericytes is mediated by endosomal proteases rather than transmembrane serine proteases as seen in the lung epithelium. We demonstrate that cardiac pericyte infection leads to upregulation of Type I interferon signaling, inflammatory markers, and mediators of vasoreactivity, along with NF-[kappa]B cell death, with viability being partially improved by cytokine inhibition. Interestingly, we demonstrate that endothelial cell exposure to infected pericytes and their supernatant can lead to upregulation of Type I interferon signaling and neutrophil and T-cell chemokines combined with dysregulation of thrombosis mediators, further linking infected cardiac pericytes with endothelial dysfunction. And finally, we present evidence of cardiac pericyte infection in COVID-19 myocarditis patients. Together, the results in my thesis work demonstrate that human cardiac pericytes are susceptible to SARS-CoV-2 infection and suggest a role of pericyte infection in COVID-19.