Applications Of Maldi Tof Spectroscopy

Author : Zongwei Cai
Publisher : Springer
ISBN 13 : 3642356656
Total Pages : 220 pages
Book Rating : 4.50/5 ( download)

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Download or read book Applications of MALDI-TOF Spectroscopy written by Zongwei Cai and published by Springer. This book was released on 2014-07-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: MALDI-ToF Mass Spectrometry for Studying Noncovalent Complexes of Biomolecules, by Stefanie Mädler, Elisabetta Boeri Erba, Renato Zenobi Application of MALDI-TOF-Mass Spectrometry to Proteome Analysis Using Stain-Free Gel Electrophoresis, by Iuliana Susnea, Bogdan Bernevic, Michael Wicke, Li Ma, Shuying Liu, Karl Schellander, Michael Przybylski MALDI Mass Spectrometry for Nucleic Acid Analysis, by Xiang Gao, Boon-Huan Tan, Richard J. Sugrue, Kai Tang Determination of Peptide and Protein Disulfide Linkages by MALDI Mass Spectrometry, by Hongmei Yang, Ning Liu, Shuying Liu MALDI In-Source Decay, from Sequencing to Imaging, by Delphine Debois, Nicolas Smargiasso, Kevin Demeure, Daiki Asakawa, Tyler A. Zimmerman, Loïc Quinton, Edwin De Pauw Advances of MALDI-TOF MS in the Analysis of Traditional Chinese Medicines, by Minghua Lu, Zongwei Cai Chemical and Biochemical Applications of MALDI TOF-MS Based on Analyzing the Small Organic Compounds, by Haoyang Wang, Zhixiong Zhao, Yinlong Guo Bioinformatic Analysis of Data Generated from MALDI Mass Spectrometry for Biomarker Discovery, by Zengyou He, Robert Z. Qi, Weichuan Yu

Author : Samira Hosseini
Publisher : Springer
ISBN 13 : 9811023565
Total Pages : 68 pages
Book Rating : 4.69/5 ( download)

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Download or read book Fundamentals of MALDI-ToF-MS Analysis written by Samira Hosseini and published by Springer. This book was released on 2016-08-18 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications.

Author : Fernando Cobo
Publisher : Academic Press
ISBN 13 : 0128144521
Total Pages : 298 pages
Book Rating : 4.27/5 ( download)

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Download or read book The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology written by Fernando Cobo and published by Academic Press. This book was released on 2018-08-03 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology presents the state-of the-art for MALDI-TOF mass spectrometry. It is a key reference defining how MALDI-TOF mass spectrometry is used in clinical settings as a diagnostic tool of microbial identification and characterization that is based on the detection of a mass of molecules. The book provides updated applications of MALDI-TOF techniques in clinical microbiology, presenting the latest information available on a technology that is now used for rapid microbial identification at relatively low cost, thus offering an alternative to conventional laboratory diagnosis and proteomic identification systems. Although the main use of the technology has, until now, been identification or typing of bacteria from a positive culture, applications in the field of virology, mycology, microbacteriology and resistances are opening up new opportunities. Presents updated applications of MALDI-TOF techniques in clinical microbiology Describes the use of mass spectrometry in the lab, the principles of the technology, preparation of samples, device calibration and maintenance, treatment of microorganisms, and quality control Presents key information for researchers, including possible uses of the technology, differences between devices, how to interpret results, and future applications Covers the topic in a systematic and comprehensive manner that is useful to both clinicians and researchers

Author : Catherine Fenselau
Publisher : OUP USA
ISBN 13 : 9780841226128
Total Pages : 0 pages
Book Rating : 4.21/5 ( download)

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Download or read book Rapid Characterization of Microorganisms by Mass Spectrometry written by Catherine Fenselau and published by OUP USA. This book was released on 2012-04-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers aspects of mass spectrometry (MS) applications for microorganism characterization in several fields: biodefense, clinical diagnostics, food safety, environmental monitoring, and chemotaxonomy/biosystematics.

Author : Haroun N. Shah
Publisher : John Wiley & Sons
ISBN 13 : 1118960238
Total Pages : 648 pages
Book Rating : 4.33/5 ( download)

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Download or read book MALDI-TOF and Tandem MS for Clinical Microbiology written by Haroun N. Shah and published by John Wiley & Sons. This book was released on 2017-03-31 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss: Challenges of Identifying Mycobacterium to the Species level Identification of Bacteroides and Other Clinically Relevant Anaerobes Identification of Species in Mixed Microbial Populations Detection of Resistance Mechanisms Proteomics as a biomarker discovery and validation platform Determination of Antimicrobial Resistance using Tandem Mass Spectrometry

Author : Plamen Demirev
Publisher : Springer
ISBN 13 : 9783319798882
Total Pages : 336 pages
Book Rating : 4.8X/5 ( download)

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Download or read book Applications of Mass Spectrometry in Microbiology written by Plamen Demirev and published by Springer. This book was released on 2018-03-30 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs. While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools. The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.

Author : Charles L. Wilkins
Publisher : CRC Press
ISBN 13 : 1439813256
Total Pages : 374 pages
Book Rating : 4.56/5 ( download)

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Download or read book Ion Mobility Spectrometry - Mass Spectrometry written by Charles L. Wilkins and published by CRC Press. This book was released on 2010-12-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical power of ion mobility spectrometry-mass spectrometry (IMS-MS) instruments is poised to advance this technology from research to analytical laboratories. Exploring these developments at this critical juncture, Ion Mobility Spectrometry-Mass Spectrometry: Theory and Applications covers the tools, techniques, and applications involved w

Author : Charlotte H. Clarke
Publisher : Humana Press
ISBN 13 : 9781617794179
Total Pages : 239 pages
Book Rating : 4.71/5 ( download)

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Download or read book SELDI-TOF Mass Spectrometry written by Charlotte H. Clarke and published by Humana Press. This book was released on 2011-11-18 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: SELDI is distinct from other TOF-MS technologies in that it couples features of chromatography and mass spectrometry, facilitating analyte enrichment and sample cleanup on an array surface. In the growing field of proteomics, SELDI technology has been widely used for biomarker discovery and characterization in diverse applications including diagnostics, drug development, and basic research. SELDI-based biomarker studies can typically be divided into four phases: discovery, validation, purification and identification, and assay development. SELDI-TOF Mass Spectrometry: Methods and Protocols provides an overview of the current applications of SELDI-TOF MS (surface enhanced laser desorption/ionization time-of-flight mass spectrometry), with an emphasis on study and experimental design, data analysis and interpretation, and assay development. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, SELDI-TOF Mass Spectrometry: Methods and Protocols will provide information on optimizing study design, experimental protocols, and data analysis and interpretation to yield robust biomarkers and biomarker assays, using examples from different disease areas.

Author : Harald Pasch
Publisher : Springer Science & Business Media
ISBN 13 : 3662050463
Total Pages : 312 pages
Book Rating : 4.60/5 ( download)

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Download or read book MALDI-TOF Mass Spectrometry of Synthetic Polymers written by Harald Pasch and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: MALDI-TOF mass spectrometry is one of the latest and most fascinating new developments in the analysis of organic compounds. Originally developed for the analysis of biomolecules, it has developed into one of the most powerful techniques for the characterization of synthetic polymers. This book describes the fundamentals of the MALDI process and the technical features of MALDI-TOF instrumentation. It reviews the application of MALDI-TOF for identification, chemical and molar mass analysis of synthetic polymers. With many examples, the monograph examines experimental protocols for the determination of endgroups, the analysis of copolymers and additives, and the coupling of liquid chromatography and MALDI-TOF in detail.

Author : Edmond de Hoffmann
Publisher : John Wiley & Sons
ISBN 13 : 1118681940
Total Pages : 502 pages
Book Rating : 4.47/5 ( download)

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Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by John Wiley & Sons. This book was released on 2013-04-03 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.