Apoptosis And Autoimmunity

Author : Keith B. Elkon
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805580363
Total Pages : 219 pages
Book Rating : 4.66/5 ( download)

DOWNLOAD NOW!

Download or read book Apoptosis and Its Relevance to Autoimmunity written by Keith B. Elkon and published by Karger Medical and Scientific Publishers. This book was released on 2006 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the recent advances in the basic mechanisms of apoptosis and the application of that knowledge to understanding the impact of defective apoptosis or defective clearance of apoptotic cells on the immune function and the expression of

Author : Joachim R. Kalden
Publisher : John Wiley & Sons
ISBN 13 : 3527605290
Total Pages : 392 pages
Book Rating : 4.93/5 ( download)

DOWNLOAD NOW!

Download or read book Apoptosis and Autoimmunity written by Joachim R. Kalden and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.

Author : Dr. Martin Herrmann
Publisher : Wiley-VCH Verlag GmbH
ISBN 13 : 9783527304424
Total Pages : 381 pages
Book Rating : 4.28/5 ( download)

DOWNLOAD NOW!

Download or read book Apoptosis and Autoimmunity written by Dr. Martin Herrmann and published by Wiley-VCH Verlag GmbH. This book was released on 2003 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up–to–date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.

Author : Katerina Chatzidionysiou
Publisher : BoD – Books on Demand
ISBN 13 : 9535121340
Total Pages : 212 pages
Book Rating : 4.43/5 ( download)

DOWNLOAD NOW!

Download or read book Autoimmunity written by Katerina Chatzidionysiou and published by BoD – Books on Demand. This book was released on 2015-06-17 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmunity is defined as an immune response against a self-antigen. This abnormal immune response can lead to tissue damage and to the development of autoimmune disease. From organ-specific autoimmune diseases, such as myasthenia gravis, to non-organ-specific, such as systemic lupus erythematosus, autoimmune diseases represent a heterogeneous group of disorders which affect approximately 6% of the population. The pathogenesis of many autoimmune diseases is complex and remains not completely understood. The aim of this book is to present current knowledge regarding pathogenic mechanisms of autoimmune diseases, clinical aspects of specific autoimmune diseases, like vitiligo, celiac disease and autoimmune liver disease, as well as insights regarding specific therapies.

Author : Andrzej Górski
Publisher : Springer Science & Business Media
ISBN 13 : 9401009813
Total Pages : 209 pages
Book Rating : 4.12/5 ( download)

DOWNLOAD NOW!

Download or read book Autoimmunity written by Andrzej Górski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an excellent review of the mechanisms underlying the phenomena of autoimmunity. It provides not only an update of the field's state of the art, but also presents new concepts in the fundamentals and treatment of autoimmune disorders. The finest example of the new approach is understanding the nature of autoimmunity and the treatment of autoimmune diseases is the introductory article. The author opposes the current dogma that autoimmune disorders should be treated with immunosuppressors, and postulates rather the activation of the immune system, which may lead to redirecting the immune response to the protective, Th-2 type of immunity. A series of articles deals with several aspects of the subject, such as the generation, progression, and regulation of autoimmune phenomena. The roles of pathogens, apoptosis, cytokines, complement components, and regulatory T cells are described, as well as the association between the immune and neurohormonal systems in major autoimmune disorders. This is not a textbook, but it is highly recommended for clinicians and university workers, and as supplementary reading for lecturers and students.

Author : Moncef Zouali
Publisher : IOS Press
ISBN 13 : 9781586033613
Total Pages : 378 pages
Book Rating : 4.11/5 ( download)

DOWNLOAD NOW!

Download or read book Frontiers in Autoimmunity written by Moncef Zouali and published by IOS Press. This book was released on 2003 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Estee Kurant
Publisher : Frontiers Media SA
ISBN 13 : 2889456889
Total Pages : 294 pages
Book Rating : 4.88/5 ( download)

DOWNLOAD NOW!

Download or read book Apoptotic Cell Clearance in Health and Disease written by Estee Kurant and published by Frontiers Media SA. This book was released on 2018-12-27 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearance of apoptotic cells is essential for proper development, homeostasis and termination of immune responses in multicellular organisms. Thus, cellular and molecular players taking part in the sequential events of this process are of great interest. Research in the last 20 years has indicated that specific ligands and receptors take part in the attraction of immune cells toward apoptotic targets and in the interactions between apoptotic cells and professional as well as non-professional phagocytes that engulf them. Moreover, phagocytosis of apoptotic cells (efferocytosis) leads to significant phenotypic changes in the engulfing cells suggesting that it is a major fate-determining event for phagocytes. Particularly, efferocytosis has an important impact on the inflammation-resolution axis as well as embryonic development and tissue morphogenesis. Deficiencies in these processes can result in health threats, such as autoimmunity, atherosclerosis, bone loss, obesity, infertility, neurodegeneration, fibrosis and cancer. This eBook brings together 24 original research and review manuscripts that cover various aspects of apoptotic cell removal during normal development and homeostasis as well as in tumorigenesis and regenerative processes following injury.

Author : M.E. Gershwin
Publisher : Elsevier
ISBN 13 : 9780080528458
Total Pages : 468 pages
Book Rating : 4.57/5 ( download)

DOWNLOAD NOW!

Download or read book Cancer and Autoimmunity written by M.E. Gershwin and published by Elsevier. This book was released on 2000-03-27 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival. This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art. This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.

Author : Christopher D. Gregory
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.50/5 ( download)

DOWNLOAD NOW!

Download or read book Apoptosis and the Immune System written by Christopher D. Gregory and published by Wiley-Liss. This book was released on 1995-03-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: By offering a broad range of views, Apoptosis and the Immune Response presents a current and complete picture of the various aspects and consequences of this phenomenon.

Author : Vijay K. Kuchroo
Publisher : Springer Science & Business Media
ISBN 13 : 1592591299
Total Pages : 421 pages
Book Rating : 4.99/5 ( download)

DOWNLOAD NOW!

Download or read book Cytokines and Autoimmune Diseases written by Vijay K. Kuchroo and published by Springer Science & Business Media. This book was released on 2001-11-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.