Antibiofilm Agents

Author : Kendra P. Rumbaugh
Publisher : Springer Science & Business Media
ISBN 13 : 3642538339
Total Pages : 495 pages
Book Rating : 4.39/5 ( download)

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Download or read book Antibiofilm Agents written by Kendra P. Rumbaugh and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

Author : Tony Romeo
Publisher : Springer Science & Business Media
ISBN 13 : 3540754180
Total Pages : 302 pages
Book Rating : 4.83/5 ( download)

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Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Author : Katsumi Matsuzaki
Publisher : Springer
ISBN 13 : 9811335885
Total Pages : 304 pages
Book Rating : 4.84/5 ( download)

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Download or read book Antimicrobial Peptides written by Katsumi Matsuzaki and published by Springer. This book was released on 2019-04-12 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.

Author : Melvin A. Shiffman
Publisher : Springer Nature
ISBN 13 : 3030030776
Total Pages : 284 pages
Book Rating : 4.73/5 ( download)

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Download or read book Biofilm, Pilonidal Cysts and Sinuses written by Melvin A. Shiffman and published by Springer Nature. This book was released on 2019-12-05 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the latest findings in the fields of biofilm, pilonidal cysts and sinuses. The first part provides detailed information on biofilm formation, antibiofilm properties and activity as well as their potential clinical application in wound management. The second part then examines pilonidal sinus disease and the surgical treatment options. Written by leading experts in the field, the book is a valuable resource for beginners and experienced surgeons alike.

Author : Sahra Kırmusaoğlu
Publisher : BoD – Books on Demand
ISBN 13 : 1789857899
Total Pages : 154 pages
Book Rating : 4.94/5 ( download)

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Download or read book Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods written by Sahra Kırmusaoğlu and published by BoD – Books on Demand. This book was released on 2019-04-03 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: To prevent bacterial adherence, invasion and infection, antimicrobials such as antibiotics are being used and vastly researched nowdays. Several factors such as natural selection, mutations in genes, the presence of efflux pumps, impermeability of the cell wall, structural changes in enzymes and receptors, biofilm formation, and quorum sensing cause microorganisms to develop resistance against antimicrobials. Isolates that synthesize extended spectrum-β-lactamases (ESBL), induced β-lactamases (IBL), carbapenamases, metallo-β-lactamases (MBLs), and New Delhi metallo-β-lactamases (NDM) have emerged. Determining virulence factors such as biofilms and the level of antimicrobial activities of antimicrobial agents alone and in combination with appropriate doses against microorganisms is very important for the diagnosis, inhibition, and prevention of microbial infection. The goal of this book is to provide information on all these topics.

Author : S. M. Abu Sayen
Publisher : CRC Press
ISBN 13 : 1771880023
Total Pages : 418 pages
Book Rating : 4.22/5 ( download)

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Download or read book Biofilm Control and Antimicrobial Agents written by S. M. Abu Sayen and published by CRC Press. This book was released on 2014-02-24 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book highlights some of the exciting research that has recently been done in the important and far-ranging field of biofilms and microbial agents. It discusses antimicrobial agents in relation to biofilm control and resistance. The book also introduces biofilm formation and mitigation strategies. It helps explores long-term solutions to the challenges imposed by biofilms.

Author : Sadik Dincer
Publisher : BoD – Books on Demand
ISBN 13 : 1789858992
Total Pages : 362 pages
Book Rating : 4.90/5 ( download)

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Download or read book Bacterial Biofilms written by Sadik Dincer and published by BoD – Books on Demand. This book was released on 2020-10-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.

Author : Ram Prasad
Publisher : Springer Nature
ISBN 13 : 3030403378
Total Pages : 461 pages
Book Rating : 4.79/5 ( download)

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Download or read book Nanostructures for Antimicrobial and Antibiofilm Applications written by Ram Prasad and published by Springer Nature. This book was released on 2020-05-12 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.

Author : Shane Rowland
Publisher :
ISBN 13 : 9781685070625
Total Pages : 0 pages
Book Rating : 4.20/5 ( download)

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Download or read book Biofilms: written by Shane Rowland and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Biofilms are naturally occurring clusters of microorganisms that stick to non-biological surfaces, like rocks in a stream. This book contains eight chapters that examine biofilms from a variety of perspectives, including the latest research in this field. Chapter One comprehensively studies the role of endophytic microbes as a potential and alternative source of antimicrobial and antibiofilm bioactive components. Chapter Two discusses how to manage oral microbial biofilm using chemical and herbal medicine. Chapter Three highlights the importance of marine biofouling and the role of coccoid cyanobacteria in this process. Chapter Four focuses on biofilm development, its impact on human health and the problems that are associated with biofilm control. Chapter Five examines microbial biofilms and their role in the environment including agriculture and bioremediation. Chapter Six reviews natural terpenoids and provides descriptions of their structural origin, biological roles and multifunctional properties, such as promoting activity on health-beneficial bacteria. Chapter Seven explains the concepts of biofilm development and the importance of honey and its implications in human health and disease control. Chapter Eight thoroughly studies the potential of honey as antibiofilm, anti-quorum sensing and dispersal agent"--

Author : Dharumadurai Dhanasekaran
Publisher : BoD – Books on Demand
ISBN 13 : 9535124358
Total Pages : 526 pages
Book Rating : 4.51/5 ( download)

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Download or read book Microbial Biofilms written by Dharumadurai Dhanasekaran and published by BoD – Books on Demand. This book was released on 2016-07-13 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.