Animal Models In Vision Research

Author :
Publisher : Academic Press
ISBN 13 : 9780080921037
Total Pages : 232 pages
Book Rating : 4.35/5 ( download)

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Download or read book Animal Models in Eye Research written by and published by Academic Press. This book was released on 2011-04-28 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery

Author :
Publisher :
ISBN 13 : 9814470392
Total Pages : pages
Book Rating : 4.91/5 ( download)

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Download or read book Myopia written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Bahram Bodaghi
Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805585842
Total Pages : 0 pages
Book Rating : 4.45/5 ( download)

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Download or read book Animal Models in Vision Research written by Bahram Bodaghi and published by S. Karger AG (Switzerland). This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary and translational approach Doubtless, inflammatory processes are involved in the pathogenesis of various ocular diseases. Autoimmunity, inflammation and infection may initiate a large spectrum of pathologic processes or contribute to their progression. In light of the recent introduction of novel therapeutic interventions in ophthalmic disorders, it is necessary to revisit experimental models of ocular inflammation and discuss the relevance of each of them to human diseases. This publication presents the contributions made during the workshop on animal models of ocular inflammation held by the International Ocular Inflammation Society in Paris in 2007. The presence of expert immunologists, molecular biologists, geneticists and physicians, dealing with specific aspects of diseases, was a major step towards a multidisciplinary and translational approach. This special issue provides validated animal models addressing pathogenesis which are the starting point of developing novel therapies based on immune mechanisms learned from these models. Ophthalmologists, immunologists, pathologists and pharmacologists interested in drug delivery for intraocular disorders will find it valuable reading.

Author : Chi-Chao Chan
Publisher : Springer
ISBN 13 : 3319194348
Total Pages : 152 pages
Book Rating : 4.49/5 ( download)

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Download or read book Animal Models of Ophthalmic Diseases written by Chi-Chao Chan and published by Springer. This book was released on 2015-12-01 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors. In conjunction, these models reflect the diversity and utility of tools used to study human disease. World expert clinicians discuss each model based on their clinical experience and the text is supported by numerous photos and diagrams. In describing the most pertinent animal models of ophthalmic diseases, this book will be of interest to ophthalmologists, vision researchers, fellows, residents and medical students.

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0124159125
Total Pages : 1108 pages
Book Rating : 4.29/5 ( download)

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Download or read book Animal Models for the Study of Human Disease written by P. Michael Conn and published by Academic Press. This book was released on 2013-05-29 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

Author : Roger W. Beuerman
Publisher : World Scientific
ISBN 13 : 9812832971
Total Pages : 420 pages
Book Rating : 4.79/5 ( download)

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Download or read book Myopia written by Roger W. Beuerman and published by World Scientific. This book was released on 2010 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myopia is the most common optical disorder in the world, and is on the rise in all parts of the world. The impact of myopia is evident as the driving force in the development of refractive surgery and of the eye glass and contact lens industries. Clearly, it is a lifestyle issue as well as a childhood disease that involves an unresolved problem in genetics. In Singapore (where myopia has reached the highest rates in the world) as well as in Taiwan and Japan, the affected group has developed greater degrees of myopia, leading to additional secondary effects on vision including blindness. This book provides a comprehensive coverage of all aspects of myopia. It is aimed at ophthalmologists, optometrists, opticians, scientists and pharmaceutical companies. The topics are uniquely treated in that they cover research at the laboratory bench as well as clinical applications. By maintaining a high level of research activity, future generations may be able to forego optical aids altogether.

Author : P. Michael Conn
Publisher : Springer Science & Business Media
ISBN 13 : 1597452858
Total Pages : 756 pages
Book Rating : 4.54/5 ( download)

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Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008-03-07 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Author : Iok-Hou Pang
Publisher : Humana
ISBN 13 : 9781493957507
Total Pages : 229 pages
Book Rating : 4.03/5 ( download)

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Download or read book Animal Models for Retinal Diseases written by Iok-Hou Pang and published by Humana. This book was released on 2016-08-23 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases. In Animal Models for Retinal Diseases, recognized experts in the field highlight valuable techniques as well as animal models for the prominent retinal diseases in order to aid in the evaluation, development, and improvement of therapeutic strategies. Beginning with an overview of the morphology of the retina, visual behavior, and genetics and genomics approaches for retinal research, the book continues by covering animal models for the research of specific human retinal diseases, e.g., retinal degeneration, age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, glaucoma, retinal ischemia, and retinal inflammation. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used approaches in the field. Vital and easy to use, Animal Models for Retinal Diseases serves to support the important future research of ocular investigators, ophthalmologists, and neuroscientists currently delving into this fascinating field of study.

Author : Joyce Tombran-Tink
Publisher : Springer Science & Business Media
ISBN 13 : 159745186X
Total Pages : 465 pages
Book Rating : 4.64/5 ( download)

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Download or read book Retinal Degenerations written by Joyce Tombran-Tink and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents new and noteworthy research into retinal diseases. It focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision. Written by renowned scientific investigators, this innovative collection of treatment strategies and technological discoveries allows for the realistic translation of research into practice.

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.69/5 ( download)

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Download or read book What Can Simple Brains Teach Us about how Vision Works written by and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vision is the process of extracting behaviorally-relevant information from patterns of light that fall on retina as the eyes sample the outside world. Traditionally, nonhuman primates (macaque monkeys, in particular) have been viewed by many as the animal model-of-choice for investigating the neuronal substrates of visual processing, not only because their visual systems closely mirror our own, but also because it is often assumed that "simpler" brains lack advanced visual processing machinery. However, this narrow view of visual neuroscience ignores the fact that vision is widely distributed throughout the animal kingdom, enabling a wide repertoire of complex behaviors in species from insects to birds, fish, and mammals. Recent years have seen a resurgence of interest in alternative animal models for vision research, especially rodents. This resurgence is partly due to the availability of increasingly powerful experimental approaches (e.g., optogenetics and two-photon imaging) that are challenging to apply to their full potential in primates. Meanwhile, even more phylogenetically distant species such as birds, fish, and insects have long been workhorse animal models for gaining insight into the core computations underlying visual processing. In many cases, these animal models are valuable precisely because their visual systems are simpler than the primate visual system. Simpler systems are often easier to understand, and studying a diversity of neuronal systems that achieve similar functions can focus attention on those computational principles that are universal and essential. This Research Topic provides a survey of the state of the art in the use of animal models of visual functions that are alternative to macaques. It includes original research, methods articles, reviews, and opinions that exploit a variety of animal models (including rodents, birds, fishes and insects, as well as small New World monkey, the marmoset) to investigate visual function. The experimental approaches covered by these studies range from psychophysics and electrophysiology to histology and genetics, testifying to the richness and depth of visual neuroscience in non-macaque species.