Allergy Bioinformatics

Author : Ailin Tao
Publisher : Springer
ISBN 13 : 9401774447
Total Pages : 255 pages
Book Rating : 4.44/5 ( download)

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Download or read book Allergy Bioinformatics written by Ailin Tao and published by Springer. This book was released on 2015-11-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the population in industrialized countries. At the same time, biotechnology is a rapidly developing field, which often involves the introduction of potentially allergenic novel proteins into drugs or foods. It is essential to avoid transferring a gene that encodes a major allergenic protein (from any source) into a drug/food crop that did not previously contain that protein. Accurately distinguishing candidate genes from allergens before transferring them into a drug or food would aid preventive efforts to curb the rising incidence of allergies. Several public databases have been created in response to increasing allergen data. The resources provided by these databases have paved the way for the creation of specialized bioinformatics tools that allow allergenicity to be predicted. The book is a useful resource for biologists and biomedical informatics scientists, as well as clinicians. Dr. Ailin Tao is the chief of Guangdong Province Key Laboratory of Allergy & Clinical Immunology, Principal Investigator of the State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital of Guangzhou Medical University; Dr. Prof. Eyal Raz is a Professor of Medicine at University of California, San Diego, La Jolla, California, USA. They collaborate very well on allergy research and this book editi ng.

Author : Ailin Tao
Publisher :
ISBN 13 : 9789401774437
Total Pages : pages
Book Rating : 4.39/5 ( download)

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Download or read book Allergy Bioinformatics written by Ailin Tao and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the population in industrialized countries. At the same time, biotechnology is a rapidly developing field, which often involves the introduction of potentially allergenic novel proteins into drugs or foods. It is essential to avoid transferring a gene that encodes a major allergenic protein (from any source) into a drug/food crop that did not previously contain that protein. Accurately distinguishing candidate genes from allergens before transferring them into a drug or food would aid preventive efforts to curb the rising incidence of allergies. Several public databases have been created in response to increasing allergen data. The resources provided by these databases have paved the way for the creation of specialized bioinformatics tools that allow allergenicity to be predicted. The book is a useful resource for biologists and biomedical informatics scientists, as well as clinicians. Dr. Ailin Tao is the chief of Guangdong Province Key Laboratory of Allergy & Clinical Immunology, Principal Investigator of the State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital of Guangzhou Medical University; Dr. Prof. Eyal Raz is a Professor of Medicine at University of California, San Diego, La Jolla, California, USA. They collaborate very well on allergy research and this book editing.

Author : Anas M. Abdel Rahman
Publisher : CRC Press
ISBN 13 : 1351647822
Total Pages : 362 pages
Book Rating : 4.23/5 ( download)

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Download or read book Food Allergy written by Anas M. Abdel Rahman and published by CRC Press. This book was released on 2017-09-01 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the recent advances and integrations in molecular technology in food research platforms, which have revolutionized the way we discover and trace potential allergens in our food and drugs and how we utilize that for diagnosis and management. These different technologies for global allergenomic profiling in different kinds of food are discussed, including mass spectrometry, chromatography, and nuclear magnetic resonance. The book also addresses multiomics research with bioinformatics strategies in food allergy in terms of allergen characterization and quantitation, and covers applications in food allergy research from discovery to routine analysis.

Author : Dietrich Kraft
Publisher : CRC Press
ISBN 13 : 9780849301360
Total Pages : 358 pages
Book Rating : 4.6X/5 ( download)

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Download or read book Molecular Biology and Immunology of Allergens written by Dietrich Kraft and published by CRC Press. This book was released on 1993-03-25 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology and Immunology of Allergens explores the characteristics of natural allergens and allergens produced by recombinant DNA techniques. The book covers important inhalant allergens such as pollen, mites, molds, and pet dander, as well as insect venoms and Chironomid hemoglobin allergens. Biological functions of allergens; the structural definition of allergens by NMR, crystallography, and computer modeling; and the production of recombinant allergens are discussed. Special attention is given to the search for the most effective expression systems in prokaryotic and eukaryotic organisms and the purification of recombinant allergens as fusion and non-fusion proteins. Other topics addressed include the production of allergen-specific T cell clones, the discovery of T cell epitopes by stimulation with overlapping peptides, and methods to induce T cell anergy by tolerogenic allergen-derived peptides. Molecular Biology and Immunology of Allergens will be an excellent reference for all researchers and clinicians in allergology, immunology, molecular biology, allergen extracting, and immunotherapy.

Author : Mohamed Abdelmoteleb
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.24/5 ( download)

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Download or read book Using Bioinformatics Tools to Evaluate Potential Risks of Food Allergy and to Predict Microbiome Functionality written by Mohamed Abdelmoteleb and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel foods and Genetically Engineered (GE) organisms are being developed for nutritional, industrial, and environmental applications. Dietary interventions have been used recently to mitigate methane emissions in ruminants. In this project, bioinformatics tools have been used to answer two main questions. The first question is the potential allergy risks for consumption of novel foods and GE organisms. The second question is the effects of dietary interventions on microbiome functionality related to methane production in ruminants. To answer the first question, regulatory authorities in the United States and Europe now expect an evaluation of new proteins in novel foods or genetically engineered organisms to be evaluated for possible allergy and Celiac disease (CeD) risk. Two microalgal species, a fungus, House Cricket, and GE Canola have been tested to evaluate potential IgE cross-reactivity. Whole genome sequencing, genomic, transcriptomic, proteomic, and immunoinformatics techniques have been used to predict potential cross-reactivity. Bioinformatics tools helped us to characterize their proteomes and critically evaluate matches to putative or proven allergens. The two microalgal species and Fusarium sp. had matches to putative allergens, which are extensively conserved in allergenic, and non-allergenic species, leading to the need for critical evaluation of the CODEX guidelines. Shrimp allergic patients may experience cross-reactions if they consume crickets. There is no reason to suspect that the GE canola would elicit allergic reactions or would induce toxic responses. In addition, we developed a sequence searchable celiac database to identify peptides and proteins for risk assessment of novel food proteins. Concerning the second question, we studied the effect of dietary nitrate and sulfate on finishing cattle performance and methane emissions. To address to question, 16S sequencing and metagenomics were used for better understanding of rumen microbiome composition and functionality. Sulfate and nitrate combination helped to reduce methane emissions, with a reduction in average daily gain, dry matter intake and gain:feed. Ruminal bacterial composition illustrated high abundance of phyla with less hydrogen production, and genera with high H2 utilization capability in fatty acids' formation, sulfate and nitrate reduction instead of methane production. Metagenomics demonstrated a significant decrease in enzymes linked to methanogenesis in COMBO diet.

Author : Jing Lin
Publisher :
ISBN 13 : 9781493969258
Total Pages : 299 pages
Book Rating : 4.50/5 ( download)

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Download or read book Food Allergens written by Jing Lin and published by . This book was released on 2017 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation This volume provides a collection of methodologies for basic research, clinical diagnosis, and treatment pertaining to food allergens, including food allergen production, purification, characterization, detection, quantification, and bioinformatics approaches to modern food allergen studies. The chapters in the book are divided into 4 parts: Part I discusses food allergen purification and production, and explores methods of producing recombinant food allergens in bacterial and yeast expression systems; Part II looks at allergen discovery, detection, and quantification covering 3 types of methods--DNA-, protein-, and cell-based methods; Part III focuses on allergenic epitope mapping; and Part IV talks about future developments concentrated around new concepts of allergenicity as an outcome of protein and food matrix interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Food Allergens: Methods and Protocols is a valuable resource for immunologists, biochemists, molecular biologists, and medical doctors and students working in the food allergy field. This book is also useful for people in the food industry, legislators, food standard agencies, allergologists, pediatricians, and clinicians in the allergic diseases and immunology fields.

Author : Claudia Traidl-Hoffmann
Publisher : Springer Nature
ISBN 13 : 3030840484
Total Pages : 489 pages
Book Rating : 4.88/5 ( download)

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Download or read book Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention written by Claudia Traidl-Hoffmann and published by Springer Nature. This book was released on 2021-11-21 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.

Author : N. Franklin Adkinson Jr.
Publisher : Elsevier Health Sciences
ISBN 13 : 0323076815
Total Pages : 1876 pages
Book Rating : 4.14/5 ( download)

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Download or read book Middleton's Allergy: Principles and Practice E-Book written by N. Franklin Adkinson Jr. and published by Elsevier Health Sciences. This book was released on 2008-11-27 with total page 1876 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. And this Expert Consult Edition offers online access to the complete contents of the 2-volume set, fully searchable, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge. Contains 400 new illustrations, 700 in all, to better illustrate complex immunology. Covers the very latest in the field, including hot topics such as food allergy and immunotherapy. Includes the latest guidelines from The National Asthma Education and Prevention Program (NAEPP). Utilizes a new, more user-friendly full-color format for easier reference. Includes online access to the entire contents of the book, fully searchable, with links to MEDLINE abstracts for all of the references.

Author : Ibrokhim Y. Abdurakhmonov
Publisher : BoD – Books on Demand
ISBN 13 : 953512546X
Total Pages : 270 pages
Book Rating : 4.64/5 ( download)

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Download or read book Bioinformatics written by Ibrokhim Y. Abdurakhmonov and published by BoD – Books on Demand. This book was released on 2016-07-27 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary bioinformatics science aims to develop methodology and analysis tools to explore large-volume of biological data using conventional and modern computer science, statistics, and mathematics, as well as pattern recognition, reconstruction, machine learning, simulation and iterative approaches, molecular modeling, folding, networking, and artificial intelligence. Written by international team of life scientists, this Bioinformatics book provides some updates on bioinformatics methods, resources, approaches, and genome analysis tools useful for molecular sciences, medicine and drug designs, as well as plant sciences and agriculture. I trust chapters of this book should provide advanced knowledge for university students, life science researchers, and interested readers on some latest developments in the bioinformatics field.

Author : Perambur S Neelakanta
Publisher : World Scientific
ISBN 13 : 9811212902
Total Pages : 684 pages
Book Rating : 4.01/5 ( download)

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Download or read book Textbook Of Bioinformatics, A: Information-theoretic Perspectives Of Bioengineering And Biological Complexes written by Perambur S Neelakanta and published by World Scientific. This book was released on 2020-08-24 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on bioinformatics is designed as an introduction to the conventional details of genomics and proteomics as well as a practical comprehension text with an extended scope on the state-of-the-art bioinformatic details pertinent to next-generation sequencing, translational/clinical bioinformatics and vaccine-design related viral informatics.It includes four major sections: (i) An introduction to bioinformatics with a focus on the fundamentals of information-theory applied to biology/microbiology, with notes on bioinformatic resources, data bases, information networking and tools; (ii) a collection of annotations on the analytics of biomolecular sequences, with pertinent details presented on biomolecular informatics, pairwise and multiple sequences, viral sequence informatics, next-generation sequencing and translational/clinical bioinformatics; (iii) a novel section on cytogenetic and organelle bioinformatics explaining the entropy-theoretics of cellular structures and the underlying informatics of synteny correlations; and (iv) a comprehensive presentation on phylogeny and species informatics.The book is aimed at students, faculty and researchers in biology, health/medical sciences, veterinary/agricultural sciences, bioengineering, biotechnology and genetic engineering. It will be a useful companion for managerial personnel in the biotechnology and bioengineering industries as well as in health/medical science.