Algebraic Statistics For Computational Biology

Author : L. Pachter
Publisher : Cambridge University Press
ISBN 13 : 9780521857000
Total Pages : 440 pages
Book Rating : 4.07/5 ( download)

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Download or read book Algebraic Statistics for Computational Biology written by L. Pachter and published by Cambridge University Press. This book was released on 2005-08-22 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, first published in 2005, offers an introduction to the application of algebraic statistics to computational biology.

Author : Seth Sullivant
Publisher : American Mathematical Society
ISBN 13 : 1470475103
Total Pages : 506 pages
Book Rating : 4.09/5 ( download)

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Download or read book Algebraic Statistics written by Seth Sullivant and published by American Mathematical Society. This book was released on 2023-11-17 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algebraic statistics uses tools from algebraic geometry, commutative algebra, combinatorics, and their computational sides to address problems in statistics and its applications. The starting point for this connection is the observation that many statistical models are semialgebraic sets. The algebra/statistics connection is now over twenty years old, and this book presents the first broad introductory treatment of the subject. Along with background material in probability, algebra, and statistics, this book covers a range of topics in algebraic statistics including algebraic exponential families, likelihood inference, Fisher's exact test, bounds on entries of contingency tables, design of experiments, identifiability of hidden variable models, phylogenetic models, and model selection. With numerous examples, references, and over 150 exercises, this book is suitable for both classroom use and independent study.

Author : Giovanni Pistone
Publisher : CRC Press
ISBN 13 : 1420035762
Total Pages : 180 pages
Book Rating : 4.66/5 ( download)

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Download or read book Algebraic Statistics written by Giovanni Pistone and published by CRC Press. This book was released on 2000-12-21 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by pioneers in this exciting new field, Algebraic Statistics introduces the application of polynomial algebra to experimental design, discrete probability, and statistics. It begins with an introduction to Grobner bases and a thorough description of their applications to experimental design. A special chapter covers the binary case

Author : Raina Robeva
Publisher : Academic Press
ISBN 13 : 0128012714
Total Pages : 382 pages
Book Rating : 4.10/5 ( download)

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Download or read book Algebraic and Discrete Mathematical Methods for Modern Biology written by Raina Robeva and published by Academic Press. This book was released on 2015-05-09 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. Examines significant questions in modern biology and their mathematical treatments Presents important mathematical concepts and tools in the context of essential biology Features material of interest to students in both mathematics and biology Presents chapters in modular format so coverage need not follow the Table of Contents Introduces projects appropriate for undergraduate research Utilizes freely accessible software for visualization, simulation, and analysis in modern biology Requires no calculus as a prerequisite Provides a complete Solutions Manual Features a companion website with supplementary resources

Author : Mathias Drton
Publisher : Springer Science & Business Media
ISBN 13 : 3764389052
Total Pages : 172 pages
Book Rating : 4.55/5 ( download)

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Download or read book Lectures on Algebraic Statistics written by Mathias Drton and published by Springer Science & Business Media. This book was released on 2009-04-25 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does an algebraic geometer studying secant varieties further the understanding of hypothesis tests in statistics? Why would a statistician working on factor analysis raise open problems about determinantal varieties? Connections of this type are at the heart of the new field of "algebraic statistics". In this field, mathematicians and statisticians come together to solve statistical inference problems using concepts from algebraic geometry as well as related computational and combinatorial techniques. The goal of these lectures is to introduce newcomers from the different camps to algebraic statistics. The introduction will be centered around the following three observations: many important statistical models correspond to algebraic or semi-algebraic sets of parameters; the geometry of these parameter spaces determines the behaviour of widely used statistical inference procedures; computational algebraic geometry can be used to study parameter spaces and other features of statistical models.

Author : Ronald W. Shonkwiler
Publisher : Springer Science & Business Media
ISBN 13 : 0387709843
Total Pages : 552 pages
Book Rating : 4.40/5 ( download)

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Download or read book Mathematical Biology written by Ronald W. Shonkwiler and published by Springer Science & Business Media. This book was released on 2009-08-04 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents mathematical biology as a field with a unity of its own, rather than only the intrusion of one science into another. The book focuses on problems of contemporary interest, such as cancer, genetics, and the rapidly growing field of genomics.

Author : Michael Stumpf
Publisher : John Wiley & Sons
ISBN 13 : 1119952042
Total Pages : 624 pages
Book Rating : 4.46/5 ( download)

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Download or read book Handbook of Statistical Systems Biology written by Michael Stumpf and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.

Author : Raina Robeva
Publisher : Academic Press
ISBN 13 : 0128140690
Total Pages : 434 pages
Book Rating : 4.97/5 ( download)

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Download or read book Algebraic and Combinatorial Computational Biology written by Raina Robeva and published by Academic Press. This book was released on 2018-10-08 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algebraic and Combinatorial Computational Biology introduces students and researchers to a panorama of powerful and current methods for mathematical problem-solving in modern computational biology. Presented in a modular format, each topic introduces the biological foundations of the field, covers specialized mathematical theory, and concludes by highlighting connections with ongoing research, particularly open questions. The work addresses problems from gene regulation, neuroscience, phylogenetics, molecular networks, assembly and folding of biomolecular structures, and the use of clustering methods in biology. A number of these chapters are surveys of new topics that have not been previously compiled into one unified source. These topics were selected because they highlight the use of technique from algebra and combinatorics that are becoming mainstream in the life sciences. Integrates a comprehensive selection of tools from computational biology into educational or research programs Emphasizes practical problem-solving through multiple exercises, projects and spinoff computational simulations Contains scalable material for use in undergraduate and graduate-level classes and research projects Introduces the reader to freely-available professional software Supported by illustrative datasets and adaptable computer code

Author : Mihai Putinar
Publisher : Springer Science & Business Media
ISBN 13 : 0387096868
Total Pages : 382 pages
Book Rating : 4.65/5 ( download)

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Download or read book Emerging Applications of Algebraic Geometry written by Mihai Putinar and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in both the theory and implementation of computational algebraic geometry have led to new, striking applications to a variety of fields of research. The articles in this volume highlight a range of these applications and provide introductory material for topics covered in the IMA workshops on "Optimization and Control" and "Applications in Biology, Dynamics, and Statistics" held during the IMA year on Applications of Algebraic Geometry. The articles related to optimization and control focus on burgeoning use of semidefinite programming and moment matrix techniques in computational real algebraic geometry. The new direction towards a systematic study of non-commutative real algebraic geometry is well represented in the volume. Other articles provide an overview of the way computational algebra is useful for analysis of contingency tables, reconstruction of phylogenetic trees, and in systems biology. The contributions collected in this volume are accessible to non-experts, self-contained and informative; they quickly move towards cutting edge research in these areas, and provide a wealth of open problems for future research.

Author : Giovanni Pistone
Publisher : Chapman and Hall/CRC
ISBN 13 : 9781584882046
Total Pages : 0 pages
Book Rating : 4.42/5 ( download)

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Download or read book Algebraic Statistics written by Giovanni Pistone and published by Chapman and Hall/CRC. This book was released on 2000-12-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by pioneers in this exciting new field, Algebraic Statistics introduces the application of polynomial algebra to experimental design, discrete probability, and statistics. It begins with an introduction to Gröbner bases and a thorough description of their applications to experimental design. A special chapter covers the binary case with new application to coherent systems in reliability and two level factorial designs. The work paves the way, in the last two chapters, for the application of computer algebra to discrete probability and statistical modelling through the important concept of an algebraic statistical model. As the first book on the subject, Algebraic Statistics presents many opportunities for spin-off research and applications and should become a landmark work welcomed by both the statistical community and its relatives in mathematics and computer science.