Acute Exposure Guideline Levels For Selected Airborne Chemicals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030915233X
Total Pages : 465 pages
Book Rating : 4.34/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2010-03-18 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030917774X
Total Pages : 320 pages
Book Rating : 4.40/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2008-09-26 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the sixth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and includes AEGLs for chemicals such as ammonia, nickel carbonyl and phosphine, among others. At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309182700
Total Pages : 292 pages
Book Rating : 4.06/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2002-10-07 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews toxicity documents on five chemicals that can be released in the air from accidents at chemical plants, storage sites, or during transportation. The documents were prepared by the National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances and were evaluated for their scientific validity, comprehensives, internal consistency, and conformance to the 1993 guidelines report.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309290252
Total Pages : 293 pages
Book Rating : 4.58/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2013-01-28 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the request of the Department of Defense and the Environmental Protection Agency, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for several chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies, such as accidental or intentional chemical releases in community, workplace, transportation, and military settings, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 13 includes AEGLs for boron trifluoride, bromoacetone, chloroacetone, hexafluoroacetone, perchloryl fluoride, piperidine, propargyl alcohol, trimethoxysilane and tetramethoxysilane, and trimethylbenzenes.

Author :
Publisher :
ISBN 13 : 9780309072946
Total Pages : pages
Book Rating : 4.48/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309170869
Total Pages : 224 pages
Book Rating : 4.64/5 ( download)

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Download or read book Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals written by National Research Council and published by National Academies Press. This book was released on 2001-05-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures. The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment. It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routesâ€"both oral and dermalâ€"as well as risk assessors in the government, academe, and private industry.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309283086
Total Pages : 291 pages
Book Rating : 4.83/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2013-05-26 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely hazardous substances (EHSs) can be released accidentally as a result of result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. As part of its efforts to develop acute exposure guideline levels for EHSs, EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001, providing updated procedures, methodologies, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances and the Committee on Acute Exposure Guideline Levels (AEGLs) in developing the AEGL values. Using the 1993 and 2001 NRC guidelines reports, the NAC-consisting of members from EPA, the Department of Defense (DOD), the Department of Energy (DOE), the Department of Transportation (DOT), other federal and state governments, the chemical industry, academia, and other organizations from the private sector-has developed AEGLs for more than 270 EHSs. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology (COT) the Committee on Acute Exposure Guideline Levels, which prepared this report. This report is the fourteenth volume in that series. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 14 summarizes the committee's conclusions and recommendations.

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309449154
Total Pages : 195 pages
Book Rating : 4.51/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-26 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely hazardous substances can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where these substances are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 20 reviews and updates the technical support document on acute exposure guideline levels (AEGLs) for selected chloroformates. This update focuses on establishing AEGL-3 values for n-propyl chloroformate and isopropyl chloroformate, but will also consider whether any new data are available that would affect the proposed values for the other 10 chloroformates. AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three levels - AEGL-1, AEGL-2, and AEGL-3 - are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309368979
Total Pages : 224 pages
Book Rating : 4.71/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2015-04-09 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely hazardous substances can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where these substances are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 19 identifies, reviews, and interprets relevant toxicologic and other scientific data for selected AEGL documents for cyanide salts, diketene, methacrylaldehyde, pentaborane, tellurium hexafluoride, and tetrafluoroethylene in order to develop acute exposure guideline levels (AEGLs) for these high-priority, acutely toxic chemicals. AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three levels - AEGL-1, AEGL-2, and AEGL-3 - are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309178908
Total Pages : 292 pages
Book Rating : 4.07/5 ( download)

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Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2007-02-27 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1993, the National Research Council's Committee on Toxicology developed criteria and methods for EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) to develop community emergency exposure levels for extremely hazardous substances for the general population. A few years later, the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC)â€"composed of members of EPA, DOD, other federal and state agencies, industry, academia, and other organizationsâ€"was established to identify, review, and interpret toxicologic and other scientific data to develop acute exposure guidelines (AEGLs) for high-priority, acutely toxic chemicals. Three levelsâ€"AEGL-1, AEGL-2, and AEGL-3 are developed for each of five exposure periods (10 min, 30 min, 1 hr, 4 hr, and 8 hr) and are distinguished by varying degrees of severity of toxic effects. This current report reviews the NAC reports for their scientific validity, completeness, and consistency with the NRC guideline reports developed in 1993 and 2001. This report is the fifth volume in the series and covers AEGLs for chlorine dioxide, chlorine trifluoride, cyclohexylamine, ethylenediamine, hydrofluoroether-7100, and tetranitromethane. It concludes that the AEGLs developed by NAC are scientifically valid and consistent with the NRC guideline reports. AEGLs are needed for a wide range of planning, response, and prevention applications. These values provide data critical to evacuation decisions and discussions between community leaders and industries as they seek ways to minimize the health impact should the chemical release occur. Some of the finalized AEGLs have been officially adopted by the Department of the Army, FEMA, and the Department of Transportation as the official levels for use by those agencies.