A Mechanistic Characterization Of The Regulated Degradation Of The Yeast 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase Hmg2p

Author : Richard George Gardner
Publisher :
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.59/5 ( download)

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Download or read book A Mechanistic Characterization of the Regulated Degradation of the Yeast 3-hydroxy-3-methylglutaryl Coenzyme A Reductase, Hmg2p written by Richard George Gardner and published by . This book was released on 2000 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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ISBN 13 :
Total Pages : 782 pages
Book Rating : 4.59/5 ( download)

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Download or read book Dissertation Abstracts International written by and published by . This book was released on 2000 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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ISBN 13 :
Total Pages : 796 pages
Book Rating : 4.06/5 ( download)

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Download or read book Genetics Abstracts written by and published by . This book was released on 2000 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.05/5 ( download)

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Download or read book Molecular Biology of the Cell written by and published by . This book was released on 1996 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Paul Harrewijn
Publisher : Springer Science & Business Media
ISBN 13 : 9401007675
Total Pages : 445 pages
Book Rating : 4.72/5 ( download)

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Download or read book Natural Terpenoids as Messengers written by Paul Harrewijn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to books on specific bioactive compounds, this book deals with the role of mevalonic acid metabolites (isoprenoids and their derived structures) in metabolism, development, and functions of organisms, which, though diverse, show various levels of communication. Different disciplines are brought together in a discussion of the messenger functions of terpenoids within and between organisms belonging to five biological kingdoms: bacteria, fungi, plants, insects, and vertebrates (including humans). The present volume covers evolutionary aspects of terpenoids in plant physiology, plant-insect relationships, semiochemicals, and in life sciences, with special emphasis on cancer research and treatment. The book provides proposals for multidisciplinary model systems for the study of interrelationships of organisms utilizing terpenoid messengers, and discusses novel strategies for insect control and multifactor treatments of cancer utilizing terpenoids. This book is of interest to scientists, and students at an advanced level: biologists, plant breeders, pharmacologists, specialists in medical fields, especially oncologists, physicians in general, and anyone with a basic biochemical and physiological knowledge.

Author : Douglas L. Mayers
Publisher : Springer
ISBN 13 : 3319467182
Total Pages : 773 pages
Book Rating : 4.84/5 ( download)

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Download or read book Antimicrobial Drug Resistance written by Douglas L. Mayers and published by Springer. This book was released on 2017-06-19 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 9811055114
Total Pages : 412 pages
Book Rating : 4.19/5 ( download)

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Download or read book Metabolic Engineering for Bioactive Compounds written by Vipin Chandra Kalia and published by Springer. This book was released on 2017-10-07 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.

Author : Benjamin Preiss
Publisher : Elsevier
ISBN 13 : 0323155146
Total Pages : 343 pages
Book Rating : 4.44/5 ( download)

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Download or read book Regulation of HMG-CoA Reductase written by Benjamin Preiss and published by Elsevier. This book was released on 2012-12-02 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulation of HMG-CoA Reductase is a nine-chapter text that focuses on the research developments in the regulation of HMG-CoA reductase enzyme and cholesterol biosynthesis. This book deals first with the role of cholesterol in the regulation of its own biosynthesis and the work involving compactin and related competitive inhibitors of HMG-CoA reductase. The subsequent chapters examine the reversible phosphorylation of HMG-CoA reductase in hormonal and other short-term physiological changes and the structure and properties of the enzyme, including evidence for modulation of enzyme activity and structure unrelated to phosphorylation. These topics are followed by discussions on the regulation of reductase in the biosynthesis of ubiquinone, dolichols, and isopentenyl-tRNA and the regulation of reductase activity in extrahepatic tissues. This text further explores the contributions made through the use of cultured cells and their genetic manipulation, with emphasis on the great potential of this approach. The concluding chapters address the status of the low-density lipoprotein pathway and related mechanisms. These chapters also consider the regulation of human hepatic HMG-CoA reductase and the special problems inherent in work with human tissues. Enzyme scientists and researchers and graduate students will find this book invaluable.

Author : N. B. Myant
Publisher : Butterworth-Heinemann
ISBN 13 : 148328123X
Total Pages : 925 pages
Book Rating : 4.30/5 ( download)

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Download or read book The Biology of Cholesterol and Related Steroids written by N. B. Myant and published by Butterworth-Heinemann. This book was released on 2014-04-24 with total page 925 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Cholesterol and Related Steroids focuses on the study of sterols in relation to living organisms. The publication first takes a look at the analysis of sterols and related steroids and the distribution of sterols and related steroids in nature, as well as the processes of extraction and separation and presence of sterols in plants, fungi, vertebrates, and invertebrates. The text then ponders on biosynthesis of sterols and metabolism of cholesterol. Topics include formation of fatty acid esters of cholesterol, steroid hormones, biosynthetic pathway to sterols, reaction mechanisms, and comparative aspects of sterol synthesis. The manuscript examines the developmental aspects of cholesterol metabolism and sterols in biological membranes. The book also reviews cholesterol synthesis in animal tissues, sterol metabolism in isolated cells, and epidemiology of the plasma cholesterol. Discussions focus on selection of statistical populations, genetic influences, regulation of sterol synthesis, general aspects of sterol metabolism, and removal of cell cholesterol in vivo. The publication is a dependable source of data for biochemists and readers interested in the biology of cholesterol and steroids.

Author : Christopher B. Fox
Publisher : Humana
ISBN 13 : 9781493964437
Total Pages : 0 pages
Book Rating : 4.37/5 ( download)

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Download or read book Vaccine Adjuvants written by Christopher B. Fox and published by Humana. This book was released on 2016-10-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.