A History of Genomics across Species, Communities and Projects

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Author :
Publisher : Springer Nature
ISBN 13 : 3031061306
Total Pages : 387 pages
Book Rating : 4.01/5 ( download)

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Book Synopsis A History of Genomics across Species, Communities and Projects by : Miguel García-Sancho

Download or read book A History of Genomics across Species, Communities and Projects written by Miguel García-Sancho and published by Springer Nature. This book was released on 2023-03-31 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers a comprehensive overview of the history of genomics across three different species and four decades, from the 1980s to the recent past. It takes an inclusive approach in order to capture not only the international initiatives to map and sequence the genomes of various organisms, but also the work of smaller-scale institutions engaged in the mapping and sequencing of yeast, human and pig DNA. In doing so, the authors expand the historiographical lens of genomics from a focus on large-scale projects to other forms of organisation. They show how practices such as genome mapping, sequence assembly and annotation are as essential as DNA sequencing in the history of genomics, and argue that existing depictions of genomics are too closely associated with the Human Genome Project. Exploring the use of genomic tools by biochemists, cell biologists, and medical and agriculturally-oriented geneticists, this book portrays the history of genomics as inseparably entangled with the day-to-day practices and objectives of these communities. The authors also uncover often forgotten actors such as the European Commission, a crucial funder and forger of collaborative networks undertaking genomic projects. In examining historical trajectories across species, communities and projects, the book provides new insights on genomics, its dramatic expansion during the late twentieth-century and its developments in the twenty-first century. Offering the first extensive critical examination of the nature and historicity of reference genomes, this book demonstrates how their affordances and limitations are shaped by the involvement or absence of particular communities in their production.

Mapping and Sequencing the Human Genome

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Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.09/5 ( download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

The Human Genome Project

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Author :
Publisher : Gareth Stevens Publishing LLLP
ISBN 13 : 153823095X
Total Pages : 34 pages
Book Rating : 4.54/5 ( download)

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Book Synopsis The Human Genome Project by : Janey Levy

Download or read book The Human Genome Project written by Janey Levy and published by Gareth Stevens Publishing LLLP. This book was released on 2018-12-15 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Genome Project was a groundbreaking, life-altering development of the late 20th century and a major evolution in science and medicine. Readers of this remarkable volume will follow the scientists of the international, collaborative research program as they map the human genome. They'll learn about the science behind the project as well as the scientific and medical possibilities opened by it. Vivid photographs support the fascinating text, and sidebars, fact boxes, and captions enrich your reader's experience.

Avian Genomics in Ecology and Evolution

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Publisher : Springer
ISBN 13 : 3030164772
Total Pages : 348 pages
Book Rating : 4.75/5 ( download)

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Book Synopsis Avian Genomics in Ecology and Evolution by : Robert H. S. Kraus

Download or read book Avian Genomics in Ecology and Evolution written by Robert H. S. Kraus and published by Springer. This book was released on 2019-06-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Birds catch the public imagination like no other group of animals; in addition, birders are perhaps the largest non-professional naturalist community. Genomics and associated bioinformatics have revolutionised daily life in just a few decades. At the same time, this development has facilitated the application of genomics technology to ecological and evolutionary studies, including biodiversity and conservation at all levels. This book reveals how the exciting toolbox of genomics offers new opportunities in all areas of avian biology. It presents contributions from prominent experts at the intersection of avian biology and genomics, and offers an ideal introduction to the world of genomics for students, biologists and bird enthusiasts alike. The book begins with a historical perspective on how genomic technology was adopted by bird ecology and evolution research groups. This led, as the book explains, to a revised understanding of avian evolution, with exciting consequences for biodiversity research as a whole. Lastly, these impacts are illustrated using seminal examples and the latest discoveries from avian biology laboratories around the world.

Vertebrate Genomes

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805581513
Total Pages : 225 pages
Book Rating : 4.16/5 ( download)

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Book Synopsis Vertebrate Genomes by : Jean-Nicolas Volff

Download or read book Vertebrate Genomes written by Jean-Nicolas Volff and published by Karger Medical and Scientific Publishers. This book was released on 2006-01-01 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of the first draft of the human genome five years ago marked the start of a new era of vertebrate comparative genomics. Genome draft sequences for chimpanzee, mouse, rat, dog, chicken as well as for several fish species are now available for the reconstruction of the evolutionary history of vertebrate genomes over the last 450 million years. This volume of Genome Dynamics presents a timely update on the past, present and future of major vertebrate genome projects. In 16 chapters, renowned specialists provide informative reviews on the current status of mammalian, bird, amphibian and fish genomics. In addition, a chapter on urochordate genomes is included. The reader will also find a useful overview of resources available for each genome as well as a description of the medical and economical perspectives opened by the different projects. This book is recommended reading for biologists interested in genetics, genomics, evolution and zoology.

The $1,000 Genome

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Publisher : Simon and Schuster
ISBN 13 : 1416569618
Total Pages : 352 pages
Book Rating : 4.19/5 ( download)

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Book Synopsis The $1,000 Genome by : Kevin Davies

Download or read book The $1,000 Genome written by Kevin Davies and published by Simon and Schuster. This book was released on 2015-08-18 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence--a comprehensive map of the 3 billion letters in our DNA--is rapidly and inevitably dropping to just $1,000. Dozens of men and women--scientists, entrepreneurs, celebrities, and patients--have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer's or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions--and many more--by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure.

Curiosity Guides: The Human Genome

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Publisher : Charlesbridge
ISBN 13 : 1607343568
Total Pages : 189 pages
Book Rating : 4.61/5 ( download)

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Book Synopsis Curiosity Guides: The Human Genome by : John Quackenbush

Download or read book Curiosity Guides: The Human Genome written by John Quackenbush and published by Charlesbridge. This book was released on 2011-02-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.

Biocode

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Publisher : American Chemical Society
ISBN 13 : 0199687757
Total Pages : 209 pages
Book Rating : 4.56/5 ( download)

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Book Synopsis Biocode by : Dawn Field

Download or read book Biocode written by Dawn Field and published by American Chemical Society. This book was released on 2015 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The living world runs on genomic software - what Dawn Field and Neil Davies call the 'biocode' - the sum of all DNA on Earth. In Biocode, they tell the story of a new age of scientific discovery: the growing global effort to read and map the biocode, and what that might mean for the future. The structure of DNA was identified in 1953, and the whole human genome was mapped by 2003. Since then the new field of genomics has mushroomed and is now operating on an industrial scale. Genomes can now be sequenced rapidly and increasingly cheaply. The genomes of large numbers of organisms from mammals to microbes, have been mapped. Getting your genome sequenced is becoming affordable for many. You too can check paternity, find out where your ancestors came from, or whether you are at risk of some diseases. Some check out the pedigree of their pets, while others turn genomes into art. A stray hair is enough to crudely reconstruct the face of the owner. From reading to constructing: the first steps to creating artificial life have already been taken. Some may find the rapidity of developments, and the potential for misuse, alarming. But they also open up unprecedented possibilities. The ability to read DNA has changed how we view ourselves and understand our place in nature. From the largest oceans, to the insides of our guts, we are able to explore the biosphere as never before, from the genome up. Sequencing technology has made the invisible world of microbes visible, and biodiversity genomics is revealing whole new worlds within us and without. The findings are transformational: we are all ecosystems now. Already the first efforts at 'barcoding' entire ecological communities and creating 'genomic observatories' have begun. The future, the authors argue, will involve biocoding the entire planet.

From Molecular Genetics to Genomics

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Author :
Publisher : Routledge
ISBN 13 : 1134334079
Total Pages : 244 pages
Book Rating : 4.70/5 ( download)

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Book Synopsis From Molecular Genetics to Genomics by : Jean-Paul Gaudillière

Download or read book From Molecular Genetics to Genomics written by Jean-Paul Gaudillière and published by Routledge. This book was released on 2004-10-07 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the rise of genomics, the life sciences have entered a new era. Maps of genomes have become the icons for a comprehensive knowledge of the organism on a previously unattained level of complexity, and the organisation of genetic knowledge in maps has been a major driving force in the establishment of the discipline. This book provides a comprehensive history of molecular genetics and genomics. The first section of the book shows how the genetic cartography of classical genetics was linked to the molecular analysis of gene structure through the introduction of new model organisms such as bacteria and through the invention of new experimental tools such as gene transfer. The second section addresses the moral and political economy of human genome sequencing in all its technical, epistemic, social and economic complexity. With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contribution to the history of genetics. A companion volume from the same editors - Classical Genetic Research and Its Legacy: The Mapping Cultures of Twentieth Century Genetics - covers the history of mapping procedures as they were developed in classical genetics.

Exploring Horizons for Domestic Animal Genomics

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Publisher : National Academies Press
ISBN 13 : 0309085055
Total Pages : 108 pages
Book Rating : 4.52/5 ( download)

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Book Synopsis Exploring Horizons for Domestic Animal Genomics by : National Research Council

Download or read book Exploring Horizons for Domestic Animal Genomics written by National Research Council and published by National Academies Press. This book was released on 2002-09-27 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognizing the important contributions that genomic analysis can make to agriculture, production and companion animal science, evolutionary biology, and human health with respect to the creation of models for genetic disorders, the National Academies convened a group of individuals to plan a public workshop that would: (1) assess these contributions; (2) identify potential research directions for existing genomics programs; and (3) highlight the opportunities of a coordinated, multi-species genomics effort for the science and policymaking communities. Their efforts culminated in a workshop sponsored by the U.S. Department of Agriculture, Department of Energy, National Science Foundation, and the National Institutes of Health. The workshop was convened on February 19, 2002. The goal of the workshop was to focus on domestic animal genomics and its integration with other genomics and functional genomics projects.